STRINGSTRING
Nqo1 Nqo1 Ins Ins Esf1 Esf1 Pik3c3 Pik3c3 Sod2 Sod2 I79_015170 I79_015170 Myd88 Myd88 Stat3 Stat3 CgPICR_001370 CgPICR_001370 Bcl2 Bcl2 I79_007693 I79_007693 Il10 Il10 Smad2 Smad2 Sirt1 Sirt1 I79_024172 I79_024172 Ache Ache I79_022257 I79_022257 Mtor Mtor I79_021949 I79_021949 Ccn2 Ccn2 I79_018057 I79_018057 I79_017574 I79_017574 Tlr4 Tlr4 Mmp9 Mmp9 Keap1 Keap1 Gclc Gclc Igf1 Igf1 Glb1 Glb1 I79_004417 I79_004417 I79_001600 I79_001600 Nos1 Nos1 I79_001093 I79_001093 I79_001092 I79_001092 Lyrm9 Lyrm9 Bmp2 Bmp2 I79_000092 I79_000092 I79_010620 I79_010620 Akr1b1 Akr1b1 Tgfb3 Tgfb3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nqo1NAD(P)H dehydrogenase [quinone] 1. (274 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
Esf1ESF1-like. (589 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (822 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
I79_015170Beta-galactosidase. (615 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
CgPICR_001370ESF1-like. (234 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Il10Interleukin-10. (178 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_024172Aldose reductase. (150 aa)
AcheCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (575 aa)
I79_022257Actin. (98 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
Ccn2Connective tissue growth factor-like protein. (348 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
I79_017574Caspase-12; Belongs to the peptidase C14A family. (729 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Keap1Kelch-like ECH-associated protein 1. (624 aa)
GclcGlutamate--cysteine ligase catalytic subunit. (584 aa)
Igf1Insulin-like growth factor I. (75 aa)
Glb1Beta-galactosidase. (650 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
I79_001093Beta-galactosidase. (659 aa)
I79_001092Beta-galactosidase. (680 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
Bmp2Bone morphogenetic protein 2. (272 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Akr1b1Aldose reductase. (316 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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