STRINGSTRING
Il15 Il15 I79_000092 I79_000092 Tgfbr2 Tgfbr2 Smad2 Smad2 Bmp7 Bmp7 Bmp6 Bmp6 Tgfb3 Tgfb3 Bmp10 Bmp10 Gdf11 Gdf11 Gdf3 Gdf3 Alb Alb Mstn Mstn I79_025220 I79_025220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Il15Interleukin; Belongs to the IL-15/IL-21 family. (155 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Bmp10Bone morphogenetic protein 10. (399 aa)
Gdf11Growth/differentiation factor 11. (268 aa)
Gdf3Growth/differentiation factor 3. (361 aa)
AlbSerum albumin. (430 aa)
MstnGrowth/differentiation factor 8. (295 aa)
I79_025220Serum albumin. (186 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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