(25 nodes) (2021) Identification of Molecules Responsible for Therapeutic Effects of Extracellular Vesicles Produced from iPSC-Derived MSCs on Sjo grens Syndrome. network (Cricetulus griseus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	Stat3	Signal transducer and activator of transcription. (770 aa)
	CgPICR_008588	Glyceraldehyde-3-phosphate dehydrogenase. (161 aa)
	CgPICR_012401	Glyceraldehyde-3-phosphate dehydrogenase. (75 aa)
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	CgPICR_017546	Glyceraldehyde-3-phosphate dehydrogenase. (127 aa)
	CgPICR_002995	Glyceraldehyde-3-phosphate dehydrogenase. (206 aa)
	Itgb1	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	CgPICR_017739	Glyceraldehyde-3-phosphate dehydrogenase. (163 aa)
	Cd9	Tetraspanin. (159 aa)
	Cd81	Tetraspanin. (236 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
	Cd63	Tetraspanin. (232 aa)
	Smad7	Mothers against decapentaplegic-like 7. (256 aa)
	Foxp3	Forkhead box protein P3. (428 aa)
	CgPICR_013910	Glyceraldehyde-3-phosphate dehydrogenase. (104 aa)
	Ywhaz	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	CgPICR_000709	Glyceraldehyde-3-phosphate dehydrogenase. (148 aa)
	CgPICR_000710	Glyceraldehyde-3-phosphate dehydrogenase. (129 aa)
	CgPICR_020194	Glyceraldehyde-3-phosphate dehydrogenase. (105 aa)
	CgPICR_002764	Glyceraldehyde-3-phosphate dehydrogenase. (77 aa)
	Il10	Interleukin-10. (178 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5. (118 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Cd40	G3GUN9	G3H8U5	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.949
Cd4	Cd63	G3GUN9	G3HRL6	T-cell surface glycoprotein CD4.	Tetraspanin.	0.736
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Cd81	G3GUN9	G3HXZ3	T-cell surface glycoprotein CD4.	Tetraspanin.	0.813
Cd4	Cd9	G3GUN9	G3GUL4	T-cell surface glycoprotein CD4.	Tetraspanin.	0.810
Cd4	CgPICR_000709	G3GUN9	G3HKA4	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_000710	G3GUN9	G3HKA3	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_002764	G3GUN9	G3HJV9	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_002995	G3GUN9	G3HZA8	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.484
Cd4	CgPICR_008588	G3GUN9	G3IHS0	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_012401	G3GUN9	G3ID55	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_013910	G3GUN9	G3HN28	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_017546	G3GUN9	G3I044	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_017739	G3GUN9	G3HYZ4	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.488
Cd4	CgPICR_020194	G3GUN9	G3HK68	T-cell surface glycoprotein CD4.	Glyceraldehyde-3-phosphate dehydrogenase.	0.430
Cd4	Foxp3	G3GUN9	G3HNB1	T-cell surface glycoprotein CD4.	Forkhead box protein P3.	0.966
Cd4	IL2	G3GUN9	G3HTL8	T-cell surface glycoprotein CD4.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.974
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Itgb1	G3GUN9	G3HZ55	T-cell surface glycoprotein CD4.	Integrin beta; Belongs to the integrin beta chain family.	0.465