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Glul-2 Glul-2 Slc30a10 Slc30a10 I79_001019 I79_001019 Lyrm9 Lyrm9 Nos1 Nos1 I79_001600 I79_001600 Slc1a2 Slc1a2 Map1a Map1a Arg2 Arg2 I79_004417 I79_004417 Map1s Map1s Keap1 Keap1 I79_007693 I79_007693 Efna3 Efna3 Bcl2 Bcl2 Glul Glul Map1b Map1b I79_010620 I79_010620 Mcu Mcu Slc1a3 Slc1a3 Stat3 Stat3 Becn1 Becn1 Slc1a6 Slc1a6 Bid Bid Slc1a1 Slc1a1 PPARG PPARG I79_016240 I79_016240 I79_016988 I79_016988 Tfeb Tfeb I79_017574 I79_017574 I79_018057 I79_018057 PC PC Trpc3 Trpc3 I79_018852 I79_018852 I79_021949 I79_021949 Jak2 Jak2 Nfe2 Nfe2 I79_023112 I79_023112 Mfn2 Mfn2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Glul-2Glutamine synthetase. (373 aa)
Slc30a10Zinc transporter 10. (343 aa)
I79_001019Amino acid transporter. (596 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Slc1a2Amino acid transporter. (553 aa)
Map1aMicrotubule-associated protein 1A. (2585 aa)
Arg2Arginase. (305 aa)
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Map1sMicrotubule-associated protein 1S. (870 aa)
Keap1Kelch-like ECH-associated protein 1. (624 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Efna3Ephrin-A3. (53 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
GlulGlutamine synthetase; Belongs to the glutamine synthetase family. (297 aa)
Map1bMicrotubule-associated protein 1B. (2371 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
McuCoiled-coil domain-containing protein 109A. (219 aa)
Slc1a3Amino acid transporter. (529 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Becn1Beclin-1. (448 aa)
Slc1a6Amino acid transporter. (562 aa)
BidBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (194 aa)
Slc1a1Amino acid transporter. (492 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_016240Beclin-1. (119 aa)
I79_016988Ceruloplasmin; Belongs to the multicopper oxidase family. (1378 aa)
TfebTranscription factor EB-like protein. (476 aa)
I79_017574Caspase-12; Belongs to the peptidase C14A family. (729 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
Trpc3Short transient receptor potential channel 3; Belongs to the cyclin family. (1401 aa)
I79_018852Amino acid transporter. (158 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
Nfe2Transcription factor NF-E2 45 kDa subunit. (374 aa)
I79_023112Glutamine synthetase; Belongs to the glutamine synthetase family. (130 aa)
Mfn2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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