25 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tyms	Thymidylate synthase-like protein. (307 aa)
	Jak2	Tyrosine-protein kinase. (1122 aa)
	Nox4	NADPH oxidase 4. (130 aa)
	Hras	GTPase HRas-like protein. (189 aa)
	Rrm1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
	Rrm2	Ribonucleoside-diphosphate reductase subunit M2. (390 aa)
	Sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
	I79_015170	Beta-galactosidase. (615 aa)
	I79_015041	Thymidylate synthase. (192 aa)
	Rrm2b	Ribonucleoside-diphosphate reductase subunit M2 B. (114 aa)
	Il15	Interleukin; Belongs to the IL-15/IL-21 family. (155 aa)
	I79_009796	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
	Calr	Calreticulin. (417 aa)
	Pxdn	Peroxidasin-like. (1475 aa)
	E2f1	Transcription factor E2F1. (367 aa)
	Sirt1	NAD-dependent deacetylase sirtuin-1. (554 aa)
	Mmp9	Matrix metalloproteinase-9. (710 aa)
	Csf2	Granulocyte-macrophage colony-stimulating factor. (95 aa)
	Calr3	Calreticulin. (380 aa)
	Glb1	Beta-galactosidase. (650 aa)
	Prdx1	Peroxiredoxin-1. (199 aa)
	Mmp10	Stromelysin-2. (966 aa)
	I79_001093	Beta-galactosidase. (659 aa)
	I79_001092	Beta-galactosidase. (680 aa)
	DHFR	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Calr	Calr3	G3HCX8	G3H4H3	Calreticulin.	Calreticulin.	0.558
Calr	Jak2	G3HCX8	G3IEQ4	Calreticulin.	Tyrosine-protein kinase.	0.424
Calr3	Calr	G3H4H3	G3HCX8	Calreticulin.	Calreticulin.	0.558
Csf2	Il15	G3H567	G3HJ60	Granulocyte-macrophage colony-stimulating factor.	Interleukin; Belongs to the IL-15/IL-21 family.	0.663
Csf2	Jak2	G3H567	G3IEQ4	Granulocyte-macrophage colony-stimulating factor.	Tyrosine-protein kinase.	0.706
Csf2	Mmp9	G3H567	G3H8V1	Granulocyte-macrophage colony-stimulating factor.	Matrix metalloproteinase-9.	0.421
Csf2	Pxdn	G3H567	G3HBI1	Granulocyte-macrophage colony-stimulating factor.	Peroxidasin-like.	0.401
DHFR	E2f1	Q2MH30	G3HAM7	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Transcription factor E2F1.	0.482
DHFR	I79_015041	Q2MH30	G3HVQ1	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Thymidylate synthase.	0.999
DHFR	Rrm1	Q2MH30	G3I3B7	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.610
DHFR	Sod2	Q2MH30	G3HWB8	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.534
DHFR	Tyms	Q2MH30	G3IFY1	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Thymidylate synthase-like protein.	0.999
E2f1	DHFR	G3HAM7	Q2MH30	Transcription factor E2F1.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.482
E2f1	Rrm1	G3HAM7	G3I3B7	Transcription factor E2F1.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.404
E2f1	Rrm2	G3HAM7	G3I2K8	Transcription factor E2F1.	Ribonucleoside-diphosphate reductase subunit M2.	0.469
E2f1	Rrm2b	G3HAM7	G3HKZ9	Transcription factor E2F1.	Ribonucleoside-diphosphate reductase subunit M2 B.	0.441
E2f1	Sirt1	G3HAM7	G3HAB1	Transcription factor E2F1.	NAD-dependent deacetylase sirtuin-1.	0.660
Hras	Jak2	G3I3F4	G3IEQ4	GTPase HRas-like protein.	Tyrosine-protein kinase.	0.730
I79_009796	Mmp10	G3HGQ6	G3GUV4	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	Stromelysin-2.	0.632
I79_009796	Mmp9	G3HGQ6	G3H8V1	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	Matrix metalloproteinase-9.	0.638