(20 nodes) (2021) DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis. network (Cricetulus griseus)

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Your Input:
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)
	Il17a	Interleukin-17A. (158 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	I79_016164	P-selectin. (1330 aa)
	Lyn	Tyrosine-protein kinase. (289 aa)
	Mog	Myelin-oligodendrocyte glycoprotein. (218 aa)
	Acod1	Immune-responsive gene 1 protein. (290 aa)
	St3gal4	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase; Belongs to the glycosyltransferase 29 family. (359 aa)
	Hck	Tyrosine-protein kinase. (503 aa)
	Nfatc1	Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa)
	Cd86	T-lymphocyte activation antigen CD86. (269 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5. (118 aa)
	Ctsk	Cathepsin K. (87 aa)
	Src	Tyrosine-protein kinase. (536 aa)
	Calcr	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (539 aa)
	Tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (776 aa)
	Csf1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
	Tlr7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
	St3gal6	Type 2 lactosamine alpha-2,3-sialyltransferase; Belongs to the glycosyltransferase 29 family. (320 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acod1	IL1B	G3HI30	G3I1B0	Immune-responsive gene 1 protein.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.406
Acod1	Tnfaip3	G3HI30	G3GW61	Immune-responsive gene 1 protein.	Tumor necrosis factor, alpha-induced protein 3.	0.648
Calcr	Ctsk	G3GXI2	G3H2X4	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Cathepsin K.	0.722
Calcr	Nfatc1	G3GXI2	G3HCQ9	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Nuclear factor of activated T-cells, cytoplasmic 1.	0.716
Cd4	Cd40	G3GUN9	G3H8U5	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.949
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Cd86	G3GUN9	G3HAJ6	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD86.	0.955
Cd4	Csf1	G3GUN9	G3IHR6	T-cell surface glycoprotein CD4.	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...]	0.778
Cd4	Ctsk	G3GUN9	G3H2X4	T-cell surface glycoprotein CD4.	Cathepsin K.	0.494
Cd4	Hck	G3GUN9	G3HE98	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.709
Cd4	I79_016164	G3GUN9	G3HYM3	T-cell surface glycoprotein CD4.	P-selectin.	0.763
Cd4	IL1B	G3GUN9	G3I1B0	T-cell surface glycoprotein CD4.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.872
Cd4	Il17a	G3GUN9	G3I1H2	T-cell surface glycoprotein CD4.	Interleukin-17A.	0.888
Cd4	Lyn	G3GUN9	G3I2D1	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.612
Cd4	Mog	G3GUN9	G3HVU5	T-cell surface glycoprotein CD4.	Myelin-oligodendrocyte glycoprotein.	0.850
Cd4	Nfatc1	G3GUN9	G3HCQ9	T-cell surface glycoprotein CD4.	Nuclear factor of activated T-cells, cytoplasmic 1.	0.483
Cd4	Src	G3GUN9	G3GXX7	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.840
Cd4	Tlr7	G3GUN9	G3I9Z2	T-cell surface glycoprotein CD4.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.912
Cd40	Cd4	G3H8U5	G3GUN9	Tumor necrosis factor receptor superfamily member 5.	T-cell surface glycoprotein CD4.	0.949
Cd40	Cd80	G3H8U5	G3I1J7	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD80.	0.963