STRINGSTRING
Ifng Ifng Edn1 Edn1 Hk3 Hk3 Hk1 Hk1 Hkdc1 Hkdc1 Il15 Il15 Stat3 Stat3 PPARG PPARG Oga Oga Ins Ins I79_015980 I79_015980 Adm Adm Hdac4 Hdac4 Srf Srf I79_016988 I79_016988 Serpina1 Serpina1 Stim1 Stim1 I79_019286 I79_019286 Rbpj Rbpj I79_021377 I79_021377 Hk2 Hk2 Ar Ar ICAM1 ICAM1 Lbp Lbp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
Edn1Endothelin-1. (202 aa)
Hk3Hexokinase-3. (867 aa)
Hk1Hexokinase-1. (917 aa)
Hkdc1Putative hexokinase HKDC1. (925 aa)
Il15Interleukin; Belongs to the IL-15/IL-21 family. (155 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
OgaBifunctional protein NCOAT. (842 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
I79_015980Leptin receptor. (533 aa)
AdmProcalcitonin/adrenomedullin containing protein. (184 aa)
Hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (966 aa)
SrfSerum response factor. (361 aa)
I79_016988Ceruloplasmin; Belongs to the multicopper oxidase family. (1378 aa)
Serpina1Alpha-1-antitrypsin; Belongs to the serpin family. (412 aa)
Stim1Stromal interaction molecule 1. (716 aa)
I79_019286Androgen receptor. (295 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
I79_021377Ataxin-10. (302 aa)
Hk2Hexokinase-2. (704 aa)
ArAndrogen receptor. (517 aa)
ICAM1Intercellular adhesion molecule 1. (527 aa)
LbpLipopolysaccharide-binding protein. (916 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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