(14 nodes) (2021) Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells. network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Hk3	Hexokinase-3. (867 aa)
	Txnip	Thioredoxin-interacting protein. (229 aa)
	Pkm	Pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
	Hk1	Hexokinase-1. (917 aa)
	Hkdc1	Putative hexokinase HKDC1. (925 aa)
	Pklr	Pyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
	I79_016952	Nicotinamide phosphoribosyltransferase. (401 aa)
	PC	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
	I79_020424	Pyruvate kinase; Belongs to the pyruvate kinase family. (258 aa)
	I79_020755	Pyruvate kinase; Belongs to the pyruvate kinase family. (461 aa)
	Hk2	Hexokinase-2. (704 aa)
	I79_023874	Pyruvate kinase; Belongs to the pyruvate kinase family. (233 aa)
	DHFR	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
	Nmnat3	Nicotinamide-nucleotide adenylyltransferase. (245 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hk1	Hk2	G3H6T5	G3IGL3	Hexokinase-1.	Hexokinase-2.	0.943
Hk1	Hk3	G3H6T5	G3H184	Hexokinase-1.	Hexokinase-3.	0.949
Hk1	Hkdc1	G3H6T5	G3H6T6	Hexokinase-1.	Putative hexokinase HKDC1.	0.941
Hk1	PC	G3H6T5	G3I4L6	Hexokinase-1.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.489
Hk1	Pklr	G3H6T5	G3HC41	Hexokinase-1.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.402
Hk2	Hk1	G3IGL3	G3H6T5	Hexokinase-2.	Hexokinase-1.	0.943
Hk2	Hk3	G3IGL3	G3H184	Hexokinase-2.	Hexokinase-3.	0.932
Hk2	Hkdc1	G3IGL3	G3H6T6	Hexokinase-2.	Putative hexokinase HKDC1.	0.904
Hk2	PC	G3IGL3	G3I4L6	Hexokinase-2.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.507
Hk2	Pkm	G3IGL3	G3H3Q1	Hexokinase-2.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.441
Hk3	Hk1	G3H184	G3H6T5	Hexokinase-3.	Hexokinase-1.	0.949
Hk3	Hk2	G3H184	G3IGL3	Hexokinase-3.	Hexokinase-2.	0.932
Hk3	Hkdc1	G3H184	G3H6T6	Hexokinase-3.	Putative hexokinase HKDC1.	0.924
Hk3	PC	G3H184	G3I4L6	Hexokinase-3.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.492
Hkdc1	Hk1	G3H6T6	G3H6T5	Putative hexokinase HKDC1.	Hexokinase-1.	0.941
Hkdc1	Hk2	G3H6T6	G3IGL3	Putative hexokinase HKDC1.	Hexokinase-2.	0.904
Hkdc1	Hk3	G3H6T6	G3H184	Putative hexokinase HKDC1.	Hexokinase-3.	0.924
Hkdc1	PC	G3H6T6	G3I4L6	Putative hexokinase HKDC1.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.492
I79_016952	Nmnat3	G3I0R3	G3GSW5	Nicotinamide phosphoribosyltransferase.	Nicotinamide-nucleotide adenylyltransferase.	0.631
I79_020424	PC	G3IA08	G3I4L6	Pyruvate kinase; Belongs to the pyruvate kinase family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.417