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Irs2 | Insulin receptor substrate 2. (465 aa) | ||||
Ppara | Peroxisome proliferator-activated receptor alpha. (393 aa) | ||||
Irs1 | Insulin receptor substrate 1. (1233 aa) | ||||
Tgfb1 | Transforming growth factor beta-1. (237 aa) | ||||
Ucp3 | Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (650 aa) | ||||
Slc2a2 | Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (351 aa) | ||||
CgPICR_017317 | Insulin receptor substrate 1. (493 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa) | ||||
Fgf21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
Hif1a | Hypoxia-inducible factor 1 alpha. (820 aa) | ||||
Adipoq | Adiponectin. (248 aa) | ||||
I79_015980 | Leptin receptor. (533 aa) | ||||
Ins | Multifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa) | ||||
Insr | Insulin receptor. (114 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa) | ||||
Pdk4 | Protein-serine/threonine kinase. (178 aa) | ||||
Mc2r | Adrenocorticotropic hormone receptor. (297 aa) | ||||
Mc4r | Melanocortin receptor 4. (332 aa) | ||||
Pklr | Pyruvate kinase; Belongs to the pyruvate kinase family. (543 aa) | ||||
Pck1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa) | ||||
Igf1 | Insulin-like growth factor I. (75 aa) | ||||
Nfe2l2 | Nuclear factor erythroid 2-related factor 2. (588 aa) | ||||
B2m | Beta-2-microglobulin. (54 aa) | ||||
Apob | Apolipoprotein B-100. (3537 aa) | ||||
Lep | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
Slc2a4 | Solute carrier family 2, facilitated glucose transporter member 4. (90 aa) | ||||
Cd68 | Macrosialin. (294 aa) | ||||
Fasn | Fatty acid synthase. (2503 aa) | ||||
Klb | Beta-klotho; Belongs to the glycosyl hydrolase 1 family. (730 aa) |