STRINGSTRING
IL1B IL1B Elane Elane PANX PANX I79_024941 I79_024941 ICAM1 ICAM1 Pxn Pxn I79_001232 I79_001232 Entpd1 Entpd1 Tln2 Tln2 Calm2 Calm2 Bcl2 Bcl2 Vcam1 Vcam1 I79_020786 I79_020786 Stpg4 Stpg4 Entpd8 Entpd8 I79_018847 I79_018847 CgPICR_017756 CgPICR_017756
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
ElaneNeutrophil elastase; Belongs to the peptidase S1 family. (252 aa)
PANXPannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
I79_024941Calmodulin; Belongs to the calmodulin family. (149 aa)
ICAM1Intercellular adhesion molecule 1. (527 aa)
PxnPaxillin. (388 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
Entpd1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (269 aa)
Tln2Talin-2. (2542 aa)
Calm2Calmodulin; Belongs to the calmodulin family. (161 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Vcam1Vascular cell adhesion protein 1. (220 aa)
I79_020786Calmodulin; Belongs to the calmodulin family. (141 aa)
Stpg4Calmodulin; Belongs to the calmodulin family. (211 aa)
Entpd8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (466 aa)
I79_018847Calmodulin; Belongs to the calmodulin family. (152 aa)
CgPICR_017756Calmodulin-like protein; Belongs to the calmodulin family. (98 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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