(18 nodes) (2022) Progesterone and Inflammatory Response in the Oviduct during Physiological and Pathological Conditions. network (Cricetulus griseus)

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second shell of interactors

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Your Input:
	Il10	Interleukin-10. (178 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	Irak1	Interleukin-1 receptor-associated kinase 1. (494 aa)
	Myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
	I79_010252	Alpha-1-acid glycoprotein 1. (195 aa)
	Tlr3	Toll-like receptor 3. (164 aa)
	Irak4	Interleukin-1 receptor-associated kinase 4. (462 aa)
	Paqr7	Membrane progestin receptor alpha. (345 aa)
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)
	Csf2	Granulocyte-macrophage colony-stimulating factor. (95 aa)
	Paqr5	Membrane progestin receptor gamma. (286 aa)
	Traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Ptgs2	Prostaglandin G/H synthase 2. (604 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Esr1	Estrogen receptor. (200 aa)
	Tlr5	Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Csf2	G3GUN9	G3H567	T-cell surface glycoprotein CD4.	Granulocyte-macrophage colony-stimulating factor.	0.856
Cd4	Esr1	G3GUN9	G3GU19	T-cell surface glycoprotein CD4.	Estrogen receptor.	0.604
Cd4	IL1B	G3GUN9	G3I1B0	T-cell surface glycoprotein CD4.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.872
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Irak1	G3GUN9	G3HSV4	T-cell surface glycoprotein CD4.	Interleukin-1 receptor-associated kinase 1.	0.500
Cd4	Irak4	G3GUN9	G3IB29	T-cell surface glycoprotein CD4.	Interleukin-1 receptor-associated kinase 4.	0.502
Cd4	Myd88	G3GUN9	G3HQV3	T-cell surface glycoprotein CD4.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.879
Cd4	Ptgs2	G3GUN9	G3GWV6	T-cell surface glycoprotein CD4.	Prostaglandin G/H synthase 2.	0.555
Cd4	Tlr3	G3GUN9	G3IHU2	T-cell surface glycoprotein CD4.	Toll-like receptor 3.	0.905
Cd4	Tlr4	G3GUN9	G3I192	T-cell surface glycoprotein CD4.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.914
Cd4	Tlr5	G3GUN9	G3GRB7	T-cell surface glycoprotein CD4.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.784
Cd4	Traf6	G3GUN9	G3GZ05	T-cell surface glycoprotein CD4.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.740
Cd80	Cd4	G3I1J7	G3GUN9	T-lymphocyte activation antigen CD80.	T-cell surface glycoprotein CD4.	0.964
Cd80	Csf2	G3I1J7	G3H567	T-lymphocyte activation antigen CD80.	Granulocyte-macrophage colony-stimulating factor.	0.703
Cd80	IL1B	G3I1J7	G3I1B0	T-lymphocyte activation antigen CD80.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.644
Cd80	Ifng	G3I1J7	G3GY20	T-lymphocyte activation antigen CD80.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.860
Cd80	Il10	G3I1J7	G3HB01	T-lymphocyte activation antigen CD80.	Interleukin-10.	0.868
Cd80	Myd88	G3I1J7	G3HQV3	T-lymphocyte activation antigen CD80.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.546