(5 nodes) (2022) Increased Ifng and Il10 Expression Correlate with Disease in Rodent Models Experimentally Infected with Modoc Virus. network (Cricetulus griseus)

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Your Input:
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Il10	Interleukin-10. (178 aa)
	Rnasel	2-5A-dependent ribonuclease. (525 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	ICAM1	Intercellular adhesion molecule 1. (527 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ICAM1	Ifng	Q9ERF7	G3GY20	Intercellular adhesion molecule 1.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.752
ICAM1	Il10	Q9ERF7	G3HB01	Intercellular adhesion molecule 1.	Interleukin-10.	0.723
ICAM1	Tnf	Q9ERF7	G3HZG9	Intercellular adhesion molecule 1.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.720
Ifng	ICAM1	G3GY20	Q9ERF7	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Intercellular adhesion molecule 1.	0.752
Ifng	Il10	G3GY20	G3HB01	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin-10.	0.979
Ifng	Tnf	G3GY20	G3HZG9	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.902
Il10	ICAM1	G3HB01	Q9ERF7	Interleukin-10.	Intercellular adhesion molecule 1.	0.723
Il10	Ifng	G3HB01	G3GY20	Interleukin-10.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.979
Il10	Tnf	G3HB01	G3HZG9	Interleukin-10.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.905
Rnasel	Tnf	G3HG31	G3HZG9	2-5A-dependent ribonuclease.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.573
Tnf	ICAM1	G3HZG9	Q9ERF7	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Intercellular adhesion molecule 1.	0.720
Tnf	Ifng	G3HZG9	G3GY20	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.902
Tnf	Il10	G3HZG9	G3HB01	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	Interleukin-10.	0.905
Tnf	Rnasel	G3HZG9	G3HG31	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	2-5A-dependent ribonuclease.	0.573