STRINGSTRING
Emd Emd Jag1 Jag1 Pcsk9 Pcsk9 Syne1 Syne1 Pxn Pxn I79_001232 I79_001232 Msrb3 Msrb3 I79_005353 I79_005353 I79_005354 I79_005354 Syne2 Syne2 Tln2 Tln2 Rhoa Rhoa Sdc4 Sdc4 Jcad Jcad Dll1 Dll1 Ocln Ocln Sun1 Sun1 I79_015376 I79_015376 Sun2 Sun2 NOTCH1 NOTCH1 Klf4 Klf4 Ccn2 Ccn2 Vcam1 Vcam1 I79_022257 I79_022257 Palmd Palmd ICAM1 ICAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EmdEmerin. (186 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
Pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (691 aa)
Syne1Nesprin-1. (1959 aa)
PxnPaxillin. (388 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
Msrb3Inner nuclear membrane protein Man1. (479 aa)
I79_005353Nesprin-2. (903 aa)
I79_005354Nesprin-2. (54 aa)
Syne2Nesprin-2. (1667 aa)
Tln2Talin-2. (2542 aa)
RhoaTransforming protein RhoA. (193 aa)
Sdc4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
JcadUncharacterized protein KIAA1462. (954 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
OclnOccludin. (488 aa)
Sun1Protein unc-84-like A. (916 aa)
I79_015376Uncharacterized protein. (2072 aa)
Sun2Protein unc-84-like B. (730 aa)
NOTCH1Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2527 aa)
Klf4Krueppel-like factor 4. (474 aa)
Ccn2Connective tissue growth factor-like protein. (348 aa)
Vcam1Vascular cell adhesion protein 1. (220 aa)
I79_022257Actin. (98 aa)
PalmdPalmdelphin. (487 aa)
ICAM1Intercellular adhesion molecule 1. (527 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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