STRINGSTRING
Cd68 Cd68 Cd4 Cd4 Cd163 Cd163 Slc46a1 Slc46a1 Mtor Mtor Tlr7 Tlr7 Cd80 Cd80 Serping1 Serping1 Brca1 Brca1 Pxdn Pxdn Il10 Il10 Lck Lck
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cd68Macrosialin. (294 aa)
Cd4T-cell surface glycoprotein CD4. (447 aa)
Cd163Scavenger receptor cysteine-rich type 1 protein M130. (497 aa)
Slc46a1Proton-coupled folate transporter. (459 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
Tlr7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
Cd80T-lymphocyte activation antigen CD80. (177 aa)
Serping1Plasma protease C1 inhibitor; Belongs to the serpin family. (177 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa)
PxdnPeroxidasin-like. (1475 aa)
Il10Interleukin-10. (178 aa)
LckProto-oncogene tyrosine-protein kinase LCK. (158 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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