STRINGSTRING
Gpx8 Gpx8 Gpx7 Gpx7 Acox3 Acox3 Fasn Fasn Got1 Got1 Acoxl Acoxl Pcna Pcna Gpx3 Gpx3 Gpx1 Gpx1 Cyp7a1 Cyp7a1 I79_009215 I79_009215 I79_009669 I79_009669 Ace Ace I79_009671 I79_009671 H671_xg20748 H671_xg20748 I79_010155 I79_010155 Gpx6 Gpx6 Gpx5 Gpx5 Acox1 Acox1 PPARG PPARG I79_015109 I79_015109 Pik3c3 Pik3c3 Ins Ins Tlr4 Tlr4 Got2 Got2 Acox2 Acox2 CgPICR_017317 CgPICR_017317 Tgfb1 Tgfb1 Ccn2 Ccn2 Irs1 Irs1 I79_022390 I79_022390 Ppara Ppara I79_024369 I79_024369 I79_024562 I79_024562 I79_025345 I79_025345
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
Gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
Acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
FasnFatty acid synthase. (2503 aa)
Got1Aspartate aminotransferase. (413 aa)
AcoxlAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (597 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Gpx3Glutathione peroxidase 3. (53 aa)
Gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
I79_009215Glutathione peroxidase; Belongs to the glutathione peroxidase family. (199 aa)
I79_009669Angiotensin-converting enzyme. (605 aa)
AceAngiotensin-converting enzyme. (791 aa)
I79_009671Angiotensin-converting enzyme. (701 aa)
H671_xg20748Angiotensin-converting enzyme. (644 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
Gpx6Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
Gpx5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (192 aa)
Acox1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (556 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_015109Interleukin-6. (174 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (822 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
Got2Aspartate aminotransferase. (430 aa)
Acox2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (668 aa)
CgPICR_017317Insulin receptor substrate 1. (493 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Ccn2Connective tissue growth factor-like protein. (348 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_024369Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (386 aa)
I79_024562Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (758 aa)
I79_025345Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (463 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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