STRINGSTRING
Bcl2 Bcl2 Ulk1 Ulk1 Pfkl Pfkl Pkm Pkm Kras Kras Ccnd1 Ccnd1 Pfkp Pfkp Esr1 Esr1 Slc16a3 Slc16a3 Src Src Eif4e Eif4e Hk2 Hk2 Pfkm Pfkm I79_020539 I79_020539 Ins Ins PPARG PPARG Stat3 Stat3 Pfkfb4 Pfkfb4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Ulk1Serine/threonine-protein kinase ULK1. (999 aa)
Pfkl6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (745 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
KrasGTPase KRas. (155 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
PfkpATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (793 aa)
Esr1Estrogen receptor. (200 aa)
Slc16a3Monocarboxylate transporter 4. (469 aa)
SrcTyrosine-protein kinase. (536 aa)
Eif4eEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
Hk2Hexokinase-2. (704 aa)
PfkmATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
I79_020539Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
Pfkfb46-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4. (469 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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