STRINGSTRING
Got1 Got1 Got2 Got2 CgPICR_012401 CgPICR_012401 Ar Ar CgPICR_008588 CgPICR_008588 Lep Lep Ghrl Ghrl Fasn Fasn CgPICR_017546 CgPICR_017546 Gcg Gcg CgPICR_002995 CgPICR_002995 CgPICR_017739 CgPICR_017739 Ins Ins Insr Insr PPARG PPARG CgPICR_013910 CgPICR_013910 CgPICR_000709 CgPICR_000709 CgPICR_000710 CgPICR_000710 CgPICR_020194 CgPICR_020194 CgPICR_002764 CgPICR_002764 Neurod1 Neurod1 Hk1 Hk1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Got1Aspartate aminotransferase. (413 aa)
Got2Aspartate aminotransferase. (430 aa)
CgPICR_012401Glyceraldehyde-3-phosphate dehydrogenase. (75 aa)
ArAndrogen receptor. (517 aa)
CgPICR_008588Glyceraldehyde-3-phosphate dehydrogenase. (161 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
GhrlAppetite-regulating hormone. (100 aa)
FasnFatty acid synthase. (2503 aa)
CgPICR_017546Glyceraldehyde-3-phosphate dehydrogenase. (127 aa)
GcgSeprase; Belongs to the peptidase S9B family. (561 aa)
CgPICR_002995Glyceraldehyde-3-phosphate dehydrogenase. (206 aa)
CgPICR_017739Glyceraldehyde-3-phosphate dehydrogenase. (163 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
InsrInsulin receptor. (114 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
CgPICR_013910Glyceraldehyde-3-phosphate dehydrogenase. (104 aa)
CgPICR_000709Glyceraldehyde-3-phosphate dehydrogenase. (148 aa)
CgPICR_000710Glyceraldehyde-3-phosphate dehydrogenase. (129 aa)
CgPICR_020194Glyceraldehyde-3-phosphate dehydrogenase. (105 aa)
CgPICR_002764Glyceraldehyde-3-phosphate dehydrogenase. (77 aa)
Neurod1Neurogenic differentiation factor. (355 aa)
Hk1Hexokinase-1. (917 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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