(8 nodes) (2022) Evidence against the Human Metapneumovirus G, SH, and M2-2 Proteins as Bona Fide Interferon Antagonists. network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	Stat1	Signal transducer and activator of transcription. (749 aa)
	Tlr7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
	CgPICR_017379	Toll-like receptor 11. (916 aa)
	Tlr6	Toll-like receptor. (795 aa)
	Traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
	Mavs	Mitochondrial antiviral-signaling protein. (505 aa)
	Ada	Adenosine deaminase. (363 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CgPICR_017379	Mavs	G3IFP1	G3H421	Toll-like receptor 11.	Mitochondrial antiviral-signaling protein.	0.427
CgPICR_017379	Stat1	G3IFP1	G3I9F9	Toll-like receptor 11.	Signal transducer and activator of transcription.	0.563
CgPICR_017379	Tlr4	G3IFP1	G3I192	Toll-like receptor 11.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.509
CgPICR_017379	Tlr6	G3IFP1	G3INL2	Toll-like receptor 11.	Toll-like receptor.	0.511
CgPICR_017379	Tlr7	G3IFP1	G3I9Z2	Toll-like receptor 11.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.422
CgPICR_017379	Traf6	G3IFP1	G3GZ05	Toll-like receptor 11.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.742
Mavs	CgPICR_017379	G3H421	G3IFP1	Mitochondrial antiviral-signaling protein.	Toll-like receptor 11.	0.427
Mavs	Stat1	G3H421	G3I9F9	Mitochondrial antiviral-signaling protein.	Signal transducer and activator of transcription.	0.687
Mavs	Tlr4	G3H421	G3I192	Mitochondrial antiviral-signaling protein.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.463
Mavs	Tlr6	G3H421	G3INL2	Mitochondrial antiviral-signaling protein.	Toll-like receptor.	0.429
Mavs	Tlr7	G3H421	G3I9Z2	Mitochondrial antiviral-signaling protein.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.749
Mavs	Traf6	G3H421	G3GZ05	Mitochondrial antiviral-signaling protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.979
Stat1	CgPICR_017379	G3I9F9	G3IFP1	Signal transducer and activator of transcription.	Toll-like receptor 11.	0.563
Stat1	Mavs	G3I9F9	G3H421	Signal transducer and activator of transcription.	Mitochondrial antiviral-signaling protein.	0.687
Stat1	Tlr4	G3I9F9	G3I192	Signal transducer and activator of transcription.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.652
Stat1	Tlr6	G3I9F9	G3INL2	Signal transducer and activator of transcription.	Toll-like receptor.	0.664
Stat1	Tlr7	G3I9F9	G3I9Z2	Signal transducer and activator of transcription.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.659
Stat1	Traf6	G3I9F9	G3GZ05	Signal transducer and activator of transcription.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.694
Tlr4	CgPICR_017379	G3I192	G3IFP1	Toll-like receptor 4; Belongs to the Toll-like receptor family.	Toll-like receptor 11.	0.509
Tlr4	Mavs	G3I192	G3H421	Toll-like receptor 4; Belongs to the Toll-like receptor family.	Mitochondrial antiviral-signaling protein.	0.463