STRINGSTRING
I79_004417 I79_004417 I79_001600 I79_001600 Ccnd1 Ccnd1 I79_025345 I79_025345 I79_024562 I79_024562 I79_024369 I79_024369 Mtor Mtor I79_021949 I79_021949 I79_020089 I79_020089 I79_018425 I79_018425 I79_018057 I79_018057 Tlr4 Tlr4 Ins Ins PPARG PPARG Gfap Gfap Bcl2 Bcl2 Cd86 Cd86 Sirt1 Sirt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_004417Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
I79_001600Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (118 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
I79_025345Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (463 aa)
I79_024562Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (758 aa)
I79_024369Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (386 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_021949Caspase-3; Belongs to the peptidase C14A family. (195 aa)
I79_020089Caspase-9; Belongs to the peptidase C14A family. (689 aa)
I79_018425Chymotrypsinogen B; Belongs to the peptidase S1 family. (253 aa)
I79_018057Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
GfapGlial fibrillary acidic protein; Belongs to the intermediate filament family. (427 aa)
Bcl2Apoptosis regulator Bcl-2. (203 aa)
Cd86T-lymphocyte activation antigen CD86. (269 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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