STRINGSTRING
Lmx1b Lmx1b Sim1 Sim1 Pitx2 Pitx2 Gbx2 Gbx2 Lhx6 Lhx6 I79_020968 I79_020968 Fgf7 Fgf7 Foxa1 Foxa1 Lhx5 Lhx5 I79_019149 I79_019149 Fgf4 Fgf4 Fgf3 Fgf3 Fgf21 Fgf21 Wnt8b Wnt8b Npm3 Npm3 Foxa2 Foxa2 Nr4a2 Nr4a2 Otx2 Otx2 Lmx1a Lmx1a H671_2g6716 H671_2g6716 Fgf16 Fgf16 I79_001364 I79_001364 Fgf17 Fgf17 Foxp2 Foxp2 Fgf20 Fgf20 Pmch Pmch En2 En2 I79_006679 I79_006679 Calb2 Calb2 Fgf13 Fgf13 Fgf1 Fgf1 Fgf22 Fgf22 Foxb1 Foxb1 Foxp1 Foxp1 Fgf12 Fgf12 Dlx2 Dlx2 Fgf14 Fgf14 Fgf23 Fgf23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Lmx1bLIM homeobox transcription factor 1-beta. (233 aa)
Sim1Putative single-minded. (765 aa)
Pitx2Homeobox protein. (322 aa)
Gbx2Homeobox protein GBX-2. (222 aa)
Lhx6LIM/homeobox protein Lhx6. (363 aa)
I79_020968Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (104 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Foxa1Hepatocyte nuclear factor 3-alpha. (434 aa)
Lhx5LIM/homeobox protein Lhx5. (402 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
Wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
Nr4a2Nuclear receptor subfamily 4 group A member 2. (598 aa)
Otx2Homeobox protein OTX2. (289 aa)
Lmx1aLIM homeobox transcription factor 1-alpha. (333 aa)
H671_2g6716Calbindin-like protein. (211 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
I79_001364Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (350 aa)
Foxp2Forkhead box protein P2. (492 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
PmchPro-MCH. (151 aa)
En2Homeobox protein engrailed-like. (120 aa)
I79_006679Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
Calb2Calretinin. (271 aa)
Fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (117 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Fgf22Fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (70 aa)
Foxb1Forkhead box protein B1. (325 aa)
Foxp1Forkhead box protein P1. (696 aa)
Fgf12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (165 aa)
Dlx2Homeobox protein DLX-2. (347 aa)
Fgf14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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