(12 nodes) (2022) Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments. network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	I79_017574	Caspase-12; Belongs to the peptidase C14A family. (729 aa)
	I79_025220	Serum albumin. (186 aa)
	Alb	Serum albumin. (430 aa)
	Tlr7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1033 aa)
	Trib3	Tribbles-like 3. (353 aa)
	Ctsd	Cathepsin D; Belongs to the peptidase A1 family. (408 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Il10	Interleukin-10. (178 aa)
	Src	Tyrosine-protein kinase. (536 aa)
	Syk	Tyrosine-protein kinase. (611 aa)
	Lamb1	Laminin subunit beta-1. (1617 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alb	Cd4	G3IAL6	G3GUN9	Serum albumin.	T-cell surface glycoprotein CD4.	0.860
Alb	I79_017574	G3IAL6	G3I2E4	Serum albumin.	Caspase-12; Belongs to the peptidase C14A family.	0.409
Alb	I79_025220	G3IAL6	G3IMS5	Serum albumin.	Serum albumin.	0.960
Alb	Ifng	G3IAL6	G3GY20	Serum albumin.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.749
Alb	Il10	G3IAL6	G3HB01	Serum albumin.	Interleukin-10.	0.655
Alb	Src	G3IAL6	G3GXX7	Serum albumin.	Tyrosine-protein kinase.	0.443
Cd4	Alb	G3GUN9	G3IAL6	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	Ctsd	G3GUN9	G3I4W7	T-cell surface glycoprotein CD4.	Cathepsin D; Belongs to the peptidase A1 family.	0.423
Cd4	I79_017574	G3GUN9	G3I2E4	T-cell surface glycoprotein CD4.	Caspase-12; Belongs to the peptidase C14A family.	0.781
Cd4	I79_025220	G3GUN9	G3IMS5	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Il10	G3GUN9	G3HB01	T-cell surface glycoprotein CD4.	Interleukin-10.	0.968
Cd4	Src	G3GUN9	G3GXX7	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.840
Cd4	Syk	G3GUN9	G3HIA4	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.754
Cd4	Tlr7	G3GUN9	G3I9Z2	T-cell surface glycoprotein CD4.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.912
Ctsd	Cd4	G3I4W7	G3GUN9	Cathepsin D; Belongs to the peptidase A1 family.	T-cell surface glycoprotein CD4.	0.423
I79_017574	Alb	G3I2E4	G3IAL6	Caspase-12; Belongs to the peptidase C14A family.	Serum albumin.	0.409
I79_017574	Cd4	G3I2E4	G3GUN9	Caspase-12; Belongs to the peptidase C14A family.	T-cell surface glycoprotein CD4.	0.781
I79_017574	I79_025220	G3I2E4	G3IMS5	Caspase-12; Belongs to the peptidase C14A family.	Serum albumin.	0.413
I79_017574	Ifng	G3I2E4	G3GY20	Caspase-12; Belongs to the peptidase C14A family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.611