(8 nodes) (2023) A novel defined TLR3 agonist as an effective vaccine adjuvant. network (Cricetulus griseus)

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Your Input:
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Cd86	T-lymphocyte activation antigen CD86. (269 aa)
	Pxdn	Peroxidasin-like. (1475 aa)
	Tlr4	Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
	Cd80	T-lymphocyte activation antigen CD80. (177 aa)
	Tlr3	Toll-like receptor 3. (164 aa)
	Cd40	Tumor necrosis factor receptor superfamily member 5. (118 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Cd40	G3GUN9	G3H8U5	T-cell surface glycoprotein CD4.	Tumor necrosis factor receptor superfamily member 5.	0.949
Cd4	Cd80	G3GUN9	G3I1J7	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD80.	0.964
Cd4	Cd86	G3GUN9	G3HAJ6	T-cell surface glycoprotein CD4.	T-lymphocyte activation antigen CD86.	0.955
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Pxdn	G3GUN9	G3HBI1	T-cell surface glycoprotein CD4.	Peroxidasin-like.	0.841
Cd4	Tlr3	G3GUN9	G3IHU2	T-cell surface glycoprotein CD4.	Toll-like receptor 3.	0.905
Cd4	Tlr4	G3GUN9	G3I192	T-cell surface glycoprotein CD4.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.914
Cd40	Cd4	G3H8U5	G3GUN9	Tumor necrosis factor receptor superfamily member 5.	T-cell surface glycoprotein CD4.	0.949
Cd40	Cd80	G3H8U5	G3I1J7	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD80.	0.963
Cd40	Cd86	G3H8U5	G3HAJ6	Tumor necrosis factor receptor superfamily member 5.	T-lymphocyte activation antigen CD86.	0.968
Cd40	Ifng	G3H8U5	G3GY20	Tumor necrosis factor receptor superfamily member 5.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.902
Cd40	Tlr3	G3H8U5	G3IHU2	Tumor necrosis factor receptor superfamily member 5.	Toll-like receptor 3.	0.581
Cd40	Tlr4	G3H8U5	G3I192	Tumor necrosis factor receptor superfamily member 5.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.841
Cd80	Cd4	G3I1J7	G3GUN9	T-lymphocyte activation antigen CD80.	T-cell surface glycoprotein CD4.	0.964
Cd80	Cd40	G3I1J7	G3H8U5	T-lymphocyte activation antigen CD80.	Tumor necrosis factor receptor superfamily member 5.	0.963
Cd80	Cd86	G3I1J7	G3HAJ6	T-lymphocyte activation antigen CD80.	T-lymphocyte activation antigen CD86.	0.997
Cd80	Ifng	G3I1J7	G3GY20	T-lymphocyte activation antigen CD80.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.860
Cd80	Pxdn	G3I1J7	G3HBI1	T-lymphocyte activation antigen CD80.	Peroxidasin-like.	0.403
Cd80	Tlr3	G3I1J7	G3IHU2	T-lymphocyte activation antigen CD80.	Toll-like receptor 3.	0.648
Cd80	Tlr4	G3I1J7	G3I192	T-lymphocyte activation antigen CD80.	Toll-like receptor 4; Belongs to the Toll-like receptor family.	0.759