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Traf2 Traf2 Hk2 Hk2 Fank1 Fank1 Cul3 Cul3 Bace1 Bace1 Stat1 Stat1 Atf3 Atf3 Kmt2a Kmt2a Cebpd Cebpd Cul5 Cul5 Cul4b Cul4b Cul9 Cul9 Mif Mif PPARG PPARG Cul2 Cul2 Cebpe Cebpe Cul7 Cul7 Smad7 Smad7 Suv39h1 Suv39h1 Gata1 Gata1 Zeb1 Zeb1 Runx3 Runx3 Stat3 Stat3 Cenpt Cenpt Nedd8 Nedd8 CgPICR_001195 CgPICR_001195 E2f1 E2f1 Cul1 Cul1 Mafg Mafg I79_001487 I79_001487 Foxm1 Foxm1 Abca1 Abca1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
Hk2Hexokinase-2. (704 aa)
Fank1Fibronectin type 3 and ankyrin repeat domains 1 protein. (259 aa)
Cul3Cullin-3; Belongs to the cullin family. (746 aa)
Bace1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
Atf3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
Kmt2aHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3512 aa)
CebpdCCAAT/enhancer-binding protein. (268 aa)
Cul5Cullin-5; Belongs to the cullin family. (780 aa)
Cul4bCullin-4B; Belongs to the cullin family. (834 aa)
Cul9Cullin-9; Belongs to the cullin family. (1563 aa)
MifMacrophage migration inhibitory factor. (115 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Cul2Cullin-2; Belongs to the cullin family. (745 aa)
CebpeCCAAT/enhancer-binding protein. (281 aa)
Cul7Cullin-7; Belongs to the cullin family. (1738 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
Suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
Gata1Erythroid transcription factor-like protein. (330 aa)
Zeb1Zinc finger E-box-binding homeobox 1. (1078 aa)
Runx3Runt-related transcription factor 3. (299 aa)
Stat3Signal transducer and activator of transcription. (770 aa)
CenptCentromere protein T. (388 aa)
Nedd8NEDD8. (81 aa)
CgPICR_001195Copine-1. (537 aa)
E2f1Transcription factor E2F1. (367 aa)
Cul1Cullin-1; Belongs to the cullin family. (776 aa)
MafgTranscription factor MafG. (162 aa)
I79_001487Progesterone receptor. (741 aa)
Foxm1Forkhead box protein M1. (764 aa)
Abca1ATP-binding cassette sub-family A member 1. (2261 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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