(10 nodes) (2023) Bispecific CD33CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia. network (Cricetulus griseus)

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Your Input:
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Ifng	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
	Cars2	Putative cysteinyl-tRNA synthetase, mitochondrial. (549 aa)
	Ccr7	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	Alb	Serum albumin. (430 aa)
	I79_021949	Caspase-3; Belongs to the peptidase C14A family. (195 aa)
	Uchl1	Ubiquitin carboxyl-terminal hydrolase. (219 aa)
	I79_025220	Serum albumin. (186 aa)
	Csf3	Granulocyte colony-stimulating factor. (208 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alb	Cd4	G3IAL6	G3GUN9	Serum albumin.	T-cell surface glycoprotein CD4.	0.860
Alb	I79_021949	G3IAL6	G3IE08	Serum albumin.	Caspase-3; Belongs to the peptidase C14A family.	0.695
Alb	I79_025220	G3IAL6	G3IMS5	Serum albumin.	Serum albumin.	0.960
Alb	IL2	G3IAL6	G3HTL8	Serum albumin.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.547
Alb	Ifng	G3IAL6	G3GY20	Serum albumin.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.749
Ccr7	Cd4	G3I5N8	G3GUN9	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	T-cell surface glycoprotein CD4.	0.922
Ccr7	IL2	G3I5N8	G3HTL8	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.663
Ccr7	Ifng	G3I5N8	G3GY20	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.761
Ccr7	Uchl1	G3I5N8	G3ILR9	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Ubiquitin carboxyl-terminal hydrolase.	0.534
Cd4	Alb	G3GUN9	G3IAL6	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	Ccr7	G3GUN9	G3I5N8	T-cell surface glycoprotein CD4.	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	0.922
Cd4	Csf3	G3GUN9	G3INY3	T-cell surface glycoprotein CD4.	Granulocyte colony-stimulating factor.	0.748
Cd4	I79_021949	G3GUN9	G3IE08	T-cell surface glycoprotein CD4.	Caspase-3; Belongs to the peptidase C14A family.	0.805
Cd4	I79_025220	G3GUN9	G3IMS5	T-cell surface glycoprotein CD4.	Serum albumin.	0.860
Cd4	IL2	G3GUN9	G3HTL8	T-cell surface glycoprotein CD4.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.974
Cd4	Ifng	G3GUN9	G3GY20	T-cell surface glycoprotein CD4.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.966
Cd4	Uchl1	G3GUN9	G3ILR9	T-cell surface glycoprotein CD4.	Ubiquitin carboxyl-terminal hydrolase.	0.790
Csf3	Cd4	G3INY3	G3GUN9	Granulocyte colony-stimulating factor.	T-cell surface glycoprotein CD4.	0.748
Csf3	IL2	G3INY3	G3HTL8	Granulocyte colony-stimulating factor.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.742
Csf3	Ifng	G3INY3	G3GY20	Granulocyte colony-stimulating factor.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.794