STRINGSTRING
Suclg2 Suclg2 Idh3a Idh3a Dlat Dlat Idh3b Idh3b PDH-A1 PDH-A1 Fh Fh H671_1g1921 H671_1g1921 Pck1 Pck1 Pck2 Pck2 Mdh1 Mdh1 Dlst Dlst Ogdh Ogdh SUCLG1 SUCLG1 Cs Cs Idh3g Idh3g Sdhc Sdhc Idh1 Idh1 Sucla2 Sucla2 Dld Dld PC PC I79_018485 I79_018485 CgPICR_015813 CgPICR_015813 Sdhb Sdhb Sdha Sdha Idh2 Idh2 Aco2 Aco2 Acly Acly
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Suclg2Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial. (358 aa)
Idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
DlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (646 aa)
Idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
PDH-A1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
FhFumarate hydratase, mitochondrial. (507 aa)
H671_1g1921Dihydrolipoyl dehydrogenase, mitochondrial. (180 aa)
Pck1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
Pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
Mdh1Malate dehydrogenase. (334 aa)
DlstDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (308 aa)
Ogdh2-oxoglutarate dehydrogenase E1 component, mitochondrial. (917 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (333 aa)
CsCitrate synthase; Belongs to the citrate synthase family. (313 aa)
Idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (335 aa)
SdhcSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (132 aa)
Idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
Sucla2Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial. (238 aa)
DldDihydrolipoyl dehydrogenase. (509 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
I79_018485Isocitrate dehydrogenase [NADP] cytoplasmic. (235 aa)
CgPICR_015813Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial. (399 aa)
SdhbSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (223 aa)
SdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (653 aa)
Idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
Aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
AclyATP-citrate synthase. (59 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.