STRINGSTRING
Cxcl3 Cxcl3 Vcl Vcl Gnas Gnas Col1a2 Col1a2 Ifng Ifng I79_002944 I79_002944 Prdx1 Prdx1 Actn1 Actn1 Arg2 Arg2 Lamb3 Lamb3 Pik3r1 Pik3r1 Csf2 Csf2 Il1r1 Il1r1 Rab5a Rab5a Itgb2 Itgb2 Rab7b Rab7b Il10 Il10 Prkca Prkca Prkaca Prkaca IL12B IL12B Tgfb3 Tgfb3 Lamc2 Lamc2 Lamc1 Lamc1 C9 C9 Lama5 Lama5 Rab7a Rab7a Actn4 Actn4 Col1a1 Col1a1 I79_011199 I79_011199 Rab5c Rab5c Prkacb Prkacb Gnal Gnal Rab5b Rab5b Gna11 Gna11 Gna15 Gna15 Lama1 Lama1 I79_016198 I79_016198 Tnf Tnf Tlr4 Tlr4 IL1B IL1B Pik3ca Pik3ca Col4a2 Col4a2 Fn1 Fn1 Lamb1 Lamb1 Prkcg Prkcg Cxcl1 Cxcl1 Muc2 Muc2 Cd14 Cd14 Ptk2 Ptk2 Pik3cd Pik3cd Col4a1 Col4a1 Plcb3 Plcb3 Prkcb Prkcb Tgfb1 Tgfb1 Gnaq Gnaq Lamb2 Lamb2 I79_021217 I79_021217 Plcb2 Plcb2 I79_021638 I79_021638 Rela Rela I79_022109 I79_022109 I79_022197 I79_022197 C8g C8g Lamc3 Lamc3 I79_024865 I79_024865 Col3a1 Col3a1 Nfkb1 Nfkb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cxcl3C-X-C motif chemokine. (101 aa)
VclVinculin. (1143 aa)
GnasGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (335 aa)
Col1a2Collagen alpha-2(I) chain. (621 aa)
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (157 aa)
I79_002944Phosphatidylinositol 3-kinase regulatory subunit gamma. (460 aa)
Prdx1Peroxiredoxin-1. (199 aa)
Actn1Alpha-actinin-1. (903 aa)
Arg2Arginase. (305 aa)
Lamb3Laminin subunit beta-3. (1166 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Csf2Granulocyte-macrophage colony-stimulating factor. (95 aa)
Il1r1Interleukin-1 receptor type I. (572 aa)
Rab5aRas-related protein Rab-5A. (215 aa)
Itgb2Integrin beta. (769 aa)
Rab7bRas-related protein Rab-7b. (199 aa)
Il10Interleukin-10. (178 aa)
PrkcaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Lamc2Laminin subunit gamma-2. (221 aa)
Lamc1Laminin subunit gamma-1. (1559 aa)
C9Complement component C9. (231 aa)
Lama5Laminin subunit alpha-5. (3735 aa)
Rab7aRas-related protein Rab-7a. (207 aa)
Actn4Alpha-actinin-4. (234 aa)
Col1a1Collagen alpha-1(I) chain. (355 aa)
I79_011199Serine/threonine-protein kinase DCLK2. (980 aa)
Rab5cRas-related protein Rab-5C. (216 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GnalGuanine nucleotide-binding protein G(Olf) subunit alpha. (131 aa)
Rab5bRas-related protein Rab-5B. (215 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (301 aa)
Gna15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
Lama1Laminin subunit alpha-1. (500 aa)
I79_016198Collagen alpha-5(IV) chain. (522 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Pik3caPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (86 aa)
Col4a2Collagen alpha-2(IV) chain. (350 aa)
Fn1Fibronectin. (2486 aa)
Lamb1Laminin subunit beta-1. (1617 aa)
PrkcgProtein kinase C gamma type. (730 aa)
Cxcl1C-X-C motif chemokine. (101 aa)
Muc2Uncharacterized protein. (3519 aa)
Cd14Monocyte differentiation antigen CD14. (309 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (910 aa)
Col4a1Collagen alpha-1(IV) chain. (1614 aa)
Plcb3Phosphoinositide phospholipase C. (1231 aa)
PrkcbNon-specific serine/threonine protein kinase. (544 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (220 aa)
Lamb2Laminin subunit beta-2. (1800 aa)
I79_021217Collagen alpha-6(IV) chain. (123 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
I79_021638Guanine nucleotide-binding protein subunit alpha-14. (282 aa)
RelaTranscription factor p65. (546 aa)
I79_022109Serpin B6; Belongs to the serpin family. (378 aa)
I79_022197Laminin subunit alpha-2. (1054 aa)
C8gComplement component C8 gamma chain. (309 aa)
Lamc3Laminin subunit gamma-3. (342 aa)
I79_024865Uncharacterized protein. (233 aa)
Col3a1Collagen alpha-1(III) chain. (1051 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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