STRINGSTRING
SFF55261.1 SFF55261.1 hutG hutG SFF53417.1 SFF53417.1 SFF51749.1 SFF51749.1 SFF51222.1 SFF51222.1 hisD hisD hisA-2 hisA-2 SFF49874.1 SFF49874.1 hisG hisG hisF hisF hisC hisC SFE63567.1 SFE63567.1 SFE68770.1 SFE68770.1 hisH hisH hisA hisA SFE77019.1 SFE77019.1 SFE85288.1 SFE85288.1 SFE88293.1 SFE88293.1 SFE92315.1 SFE92315.1 hisB hisB hisI hisI SFF03396.1 SFF03396.1 SFF04679.1 SFF04679.1 SFF14345.1 SFF14345.1 SFF19564.1 SFF19564.1 SFF19590.1 SFF19590.1 SFF20726.1 SFF20726.1 SFF27552.1 SFF27552.1 SFF35143.1 SFF35143.1 SFF35666.1 SFF35666.1 hutU hutU SFF61404.1 SFF61404.1 SFF57630.1 SFF57630.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SFF55261.1Gliding motility-associated lipoprotein GldJ/gliding motility-associated lipoprotein GldJ,TIGR03530. (432 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (319 aa)
SFF53417.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (341 aa)
SFF51749.1Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (417 aa)
SFF51222.1Monoamine oxidase. (450 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
hisA-21-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (240 aa)
SFF49874.1Imidazolonepropionase. (1024 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa)
hisFCyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisCHistidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)
SFE63567.1Gliding motility-associated lipoprotein GldK/gliding motility-associated lipoprotein GldK,TIGR03529. (374 aa)
SFE68770.1Histidinol-phosphate aminotransferase. (380 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (199 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (239 aa)
SFE77019.1Imidazolonepropionase. (1142 aa)
SFE85288.1Imidazolonepropionase. (428 aa)
SFE88293.1Imidazolonepropionase. (432 aa)
SFE92315.1Histidine ammonia-lyase. (513 aa)
hisBImidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (370 aa)
hisIphosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (202 aa)
SFF03396.1Sulfatase-modifying factor enzyme 1. (147 aa)
SFF04679.1Sulfatase modifying factor 1. (268 aa)
SFF14345.1Formiminoglutamase; Belongs to the arginase family. (380 aa)
SFF19564.1Sulfatase-modifying factor enzyme 1. (114 aa)
SFF19590.1Sulfatase-modifying factor enzyme 1. (100 aa)
SFF20726.1Glutamate formiminotransferase. (316 aa)
SFF27552.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (364 aa)
SFF35143.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (254 aa)
SFF35666.1Transposase IS116/IS110/IS902 family protein. (191 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (564 aa)
SFF61404.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (313 aa)
SFF57630.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (521 aa)
Your Current Organism:
Thermoflexibacter ruber
NCBI taxonomy Id: 1003
Other names: ATCC 23103, DSM 9560, Flexibacter ruber, IFO 16677, LMG 13857, LMG:13857, NBRC 16677, T. ruber, strain GEY
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