STRINGSTRING
coaE coaE nadA nadA nadE nadE panB panB nadD nadD AEW94308.1 AEW94308.1 clpS clpS AEW94310.1 AEW94310.1 AEW94311.1 AEW94311.1 AEW94977.1 AEW94977.1 coaX coaX AEW94980.1 AEW94980.1 AEW94981.1 AEW94981.1 AEW94982.1 AEW94982.1 panC panC AEW94987.1 AEW94987.1 coaA coaA AEW96406.1 AEW96406.1 coaD coaD AEW96895.1 AEW96895.1 AEW96958.1 AEW96958.1 AEW97716.1 AEW97716.1 AEW97740.1 AEW97740.1 AEW97741.1 AEW97741.1 AEW97742.1 AEW97742.1 ribBA ribBA ribH ribH AEW97747.1 AEW97747.1 AEW97748.1 AEW97748.1 AEW97749.1 AEW97749.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (390 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (584 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (293 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (196 aa)
AEW94308.1Hypothetical protein. (198 aa)
clpSATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (100 aa)
AEW94310.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (458 aa)
AEW94311.1Nicotinamidase. (195 aa)
AEW94977.1Small membrane protein. (62 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (265 aa)
AEW94980.1Nicotinate-nucleotide pyrophosphorylase. (352 aa)
AEW94981.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (563 aa)
AEW94982.1Hypothetical protein. (309 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (301 aa)
AEW94987.1L-allo-threonine aldolase. (382 aa)
coaAPantothenate kinase. (327 aa)
AEW96406.1Hypothetical protein. (344 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (170 aa)
AEW96895.1Starvation-induced DNA protecting protein; Belongs to the Dps family. (158 aa)
AEW96958.1Putative DNA hydrolase; Belongs to the Nudix hydrolase family. (260 aa)
AEW97716.1Putative flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa)
AEW97740.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (373 aa)
AEW97741.1Riboflavin synthase subunit alpha. (205 aa)
AEW97742.1Putative integral membrane protein. (217 aa)
ribBAHypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (434 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (161 aa)
AEW97747.1Hypothetical protein. (153 aa)
AEW97748.1Integral membrane protein. (441 aa)
AEW97749.1Integral membrane protein. (363 aa)
Your Current Organism:
Streptomyces cattleya
NCBI taxonomy Id: 1003195
Other names: S. cattleya NRRL 8057 = DSM 46488, Streptomyces cattleya DSM 46488, Streptomyces cattleya DSM 46488 = NRRL 8057, Streptomyces cattleya JCM 4925, Streptomyces cattleya NBRC 14057, Streptomyces cattleya NRRL 8057, Streptomyces cattleya NRRL 8057 = DSM 46488
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