STRINGSTRING
cobD cobD cobQ cobQ AEW93413.1 AEW93413.1 AEW93414.1 AEW93414.1 AEW93415.1 AEW93415.1 cobB cobB AEW93417.1 AEW93417.1 AEW93418.1 AEW93418.1 AEW93419.1 AEW93419.1 AEW93420.1 AEW93420.1 AEW93668.1 AEW93668.1 cobT cobT cobS cobS hemA hemA hemC hemC AEW95784.1 AEW95784.1 AEW95785.1 AEW95785.1 hemL hemL AEW96560.1 AEW96560.1 hemH hemH hemE hemE AEW97052.1 AEW97052.1 AEW97053.1 AEW97053.1 AEW97427.1 AEW97427.1 AEW97636.1 AEW97636.1 cobT-2 cobT-2 AEW97639.1 AEW97639.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (312 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (502 aa)
AEW93413.1Cobaltochelatase. (1219 aa)
AEW93414.1Magnesium-chelatase subunit. (685 aa)
AEW93415.1cob(I)yrinic acid a,c-diamide adenosyltransferase. (198 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (462 aa)
AEW93417.1Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (242 aa)
AEW93418.1Precorrin-4 C11-methyltransferase. (266 aa)
AEW93419.1Precorrin methylase. (565 aa)
AEW93420.1Metal binding protein. (319 aa)
AEW93668.1Adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase. (397 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (361 aa)
cobSCobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (267 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (428 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (327 aa)
AEW95784.1uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. (539 aa)
AEW95785.1Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (323 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (376 aa)
AEW96560.1Putative cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (371 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (379 aa)
AEW97052.1Putative oxidoreductase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (525 aa)
AEW97053.1Hypothetical protein. (240 aa)
AEW97427.1Putative methyltransferase. (408 aa)
AEW97636.1precorrin-6Y C5,15-methyltransferase. (400 aa)
cobT-2Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (1043 aa)
AEW97639.1uroporphyrin-III C-methyltransferase. (407 aa)
Your Current Organism:
Streptomyces cattleya
NCBI taxonomy Id: 1003195
Other names: S. cattleya NRRL 8057 = DSM 46488, Streptomyces cattleya DSM 46488, Streptomyces cattleya DSM 46488 = NRRL 8057, Streptomyces cattleya JCM 4925, Streptomyces cattleya NBRC 14057, Streptomyces cattleya NRRL 8057, Streptomyces cattleya NRRL 8057 = DSM 46488
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