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Clhc1 Clhc1 Ap2a1 Ap2a1 Snap91 Snap91 Itsn1 Itsn1 Hip1 Hip1 Epn1 Epn1 Epn3 Epn3 Cltc Cltc Eps15l1 Eps15l1 Gak Gak Picalm Picalm Cltb Cltb Epn2 Epn2 Fcho2 Fcho2 Dnajc6 Dnajc6 Fcho1 Fcho1 Necap2 Necap2 Ap2s1 Ap2s1 ENSMAUP00000022141 ENSMAUP00000022141 Clta Clta Ap2a2 Ap2a2 Ston2 Ston2 Ap2m1 Ap2m1 Ap2b1 Ap2b1 Hip1r Hip1r Eps15 Eps15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Clhc1Clathrin heavy chain linker domain-containing protein 1. (585 aa)
Ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
Snap91Clathrin coat assembly protein AP180 isoform X3. (892 aa)
Itsn1Intersectin-1. (611 aa)
Hip1Huntingtin-interacting protein 1 isoform X2. (1008 aa)
Epn1Epsin-1 isoform X1. (576 aa)
Epn3Epsin-3 isoform X1. (633 aa)
CltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
Eps15l1Epidermal growth factor receptor substrate 15-like 1. (601 aa)
Gakcyclin-G-associated kinase isoform X2. (136 aa)
PicalmPhosphatidylinositol-binding clathrin assembly protein. (531 aa)
CltbClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (207 aa)
Epn2Epsin-2. (596 aa)
Fcho2F-BAR domain only protein 2. (774 aa)
Dnajc6Putative tyrosine-protein phosphatase auxilin isoform X1. (967 aa)
Fcho1F-BAR domain only protein 1 isoform X1. (874 aa)
Necap2Adaptin ear-binding coat-associated protein 2. (177 aa)
Ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
ENSMAUP00000022141annotation not available (231 aa)
CltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
Ap2a2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
Ston2Stonin-2 isoform X1; Belongs to the Stoned B family. (897 aa)
Ap2m1AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (441 aa)
Ap2b1AP complex subunit beta. (951 aa)
Hip1rHuntingtin-interacting protein 1-related protein. (1068 aa)
Eps15Epidermal growth factor receptor substrate 15 isoform X2. (898 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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