(57 nodes) Mixed, incl. Serotonin Neurotransmitter Release Cycle, and Synaptic vesicle fusion to presynaptic active zone membrane network (Mesocricetus auratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rimbp3	RIMS-binding protein 3-like. (1601 aa)
	Slc17a7	Vesicular glutamate transporter 1. (585 aa)
	C2cd4a	C2 calcium-dependent domain-containing protein 4A. (334 aa)
	Stx11	Syntaxin-11; Belongs to the syntaxin family. (287 aa)
	Syt4	Synaptotagmin-4. (425 aa)
	Stx19	Syntaxin-19; Belongs to the syntaxin family. (293 aa)
	Syn1	Synapsin-1 isoform X1. (706 aa)
	Slc17a8	Vesicular glutamate transporter 3. (504 aa)
	Napa	Alpha-soluble NSF attachment protein. (295 aa)
	Stx4	Syntaxin-4 isoform X2; Belongs to the syntaxin family. (298 aa)
	Vamp3	Vesicle-associated membrane protein 3. (104 aa)
	Vamp2	Vesicle-associated membrane protein 2. (115 aa)
	Stxbp2	Syntaxin-binding protein 2 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
	Stx1b	syntaxin-1B; Belongs to the syntaxin family. (292 aa)
	Slc18a2	Synaptic vesicular amine transporter. (447 aa)
	Syt10	Synaptotagmin-10. (523 aa)
	Rims3	Regulating synaptic membrane exocytosis protein 3. (300 aa)
	Stxbp1	Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (602 aa)
	Vamp5	Vesicle-associated membrane protein 5. (103 aa)
	C2cd4b	C2 calcium-dependent domain-containing protein 4B. (340 aa)
	Snap23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (202 aa)
	Syt3	Synaptotagmin-3 isoform X2. (588 aa)
	Rims1	Regulating synaptic membrane exocytosis protein 1 isoform X32. (219 aa)
	Unc13a	Protein unc-13 homolog A. (1672 aa)
	Stxbp3	Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (1051 aa)
	Rab3c	Ras-related protein Rab-3C isoform X1. (228 aa)
	Syt7	Synaptotagmin-7 isoform X2. (567 aa)
	Syt1	Synaptotagmin-1. (422 aa)
	Stx3	Syntaxin-3 isoform X1; Belongs to the syntaxin family. (289 aa)
	Rab3b	Ras-related protein Rab-3B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (219 aa)
	Rims2	Regulating synaptic membrane exocytosis protein 2. (1453 aa)
	Syn3	Synapsin-3 isoform X1. (579 aa)
	Vamp1	Vesicle-associated membrane protein 1 isoform X1. (125 aa)
	Syt13	Synaptotagmin-13. (426 aa)
	Cplx1	Complexin-1. (134 aa)
	Syt11	Synaptotagmin-11 isoform X1. (124 aa)
	Slc32a1	Vesicular inhibitory amino acid transporter. (525 aa)
	Unc13c	Protein unc-13 homolog C. (2208 aa)
	Tmem183a	Transmembrane protein 183A. (376 aa)
	Unc13b	Protein unc-13 homolog B isoform X14. (1622 aa)
	Syt12	Synaptotagmin-12 isoform X2. (421 aa)
	Syp	Synaptophysin. (313 aa)
	Slc18a3	Vesicular acetylcholine transporter. (532 aa)
	Syt6	Synaptotagmin-6 isoform X1. (546 aa)
	Slc17a5	Sialin. (495 aa)
	Slc18a1	Chromaffin granule amine transporter. (521 aa)
	Slc17a6	Vesicular glutamate transporter 2 isoform X1. (582 aa)
	Rimbp2	RIMS-binding protein 2 isoform X6. (1080 aa)
	Cplx2	Complexin-2. (134 aa)
	Snap47	Synaptosomal-associated protein 47 isoform X1. (419 aa)
	Syn2	Synapsin-2. (313 aa)
	Nsf	Vesicle-fusing ATPase. (744 aa)
	Slc18b1	MFS-type transporter SLC18B1 isoform X1. (435 aa)
	Stx2	Syntaxin-2 isoform X1; Belongs to the syntaxin family. (289 aa)
	Snap25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
	Syt16	Synaptotagmin-16. (593 aa)
	Stx1a	syntaxin-1A isoform X1; Belongs to the syntaxin family. (288 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C2cd4a	Cplx1	ENSMAUP00000001770	ENSMAUP00000013261	C2 calcium-dependent domain-containing protein 4A.	Complexin-1.	0.474
C2cd4a	Cplx2	ENSMAUP00000001770	ENSMAUP00000022139	C2 calcium-dependent domain-containing protein 4A.	Complexin-2.	0.512
C2cd4a	Rab3b	ENSMAUP00000001770	ENSMAUP00000012067	C2 calcium-dependent domain-containing protein 4A.	Ras-related protein Rab-3B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	0.589
C2cd4a	Rab3c	ENSMAUP00000001770	ENSMAUP00000011591	C2 calcium-dependent domain-containing protein 4A.	Ras-related protein Rab-3C isoform X1.	0.589
C2cd4a	Rims1	ENSMAUP00000001770	ENSMAUP00000011136	C2 calcium-dependent domain-containing protein 4A.	Regulating synaptic membrane exocytosis protein 1 isoform X32.	0.468
C2cd4a	Rims2	ENSMAUP00000001770	ENSMAUP00000012439	C2 calcium-dependent domain-containing protein 4A.	Regulating synaptic membrane exocytosis protein 2.	0.690
C2cd4a	Rims3	ENSMAUP00000001770	ENSMAUP00000008575	C2 calcium-dependent domain-containing protein 4A.	Regulating synaptic membrane exocytosis protein 3.	0.468
C2cd4a	Slc17a6	ENSMAUP00000001770	ENSMAUP00000020351	C2 calcium-dependent domain-containing protein 4A.	Vesicular glutamate transporter 2 isoform X1.	0.440
C2cd4a	Slc17a7	ENSMAUP00000001770	ENSMAUP00000000955	C2 calcium-dependent domain-containing protein 4A.	Vesicular glutamate transporter 1.	0.440
C2cd4a	Slc17a8	ENSMAUP00000001770	ENSMAUP00000005857	C2 calcium-dependent domain-containing protein 4A.	Vesicular glutamate transporter 3.	0.440
C2cd4a	Slc18a1	ENSMAUP00000001770	ENSMAUP00000020044	C2 calcium-dependent domain-containing protein 4A.	Chromaffin granule amine transporter.	0.465
C2cd4a	Slc18a2	ENSMAUP00000001770	ENSMAUP00000008045	C2 calcium-dependent domain-containing protein 4A.	Synaptic vesicular amine transporter.	0.465
C2cd4a	Slc18a3	ENSMAUP00000001770	ENSMAUP00000017970	C2 calcium-dependent domain-containing protein 4A.	Vesicular acetylcholine transporter.	0.465
C2cd4a	Slc18b1	ENSMAUP00000001770	ENSMAUP00000024406	C2 calcium-dependent domain-containing protein 4A.	MFS-type transporter SLC18B1 isoform X1.	0.465
C2cd4a	Slc32a1	ENSMAUP00000001770	ENSMAUP00000014441	C2 calcium-dependent domain-containing protein 4A.	Vesicular inhibitory amino acid transporter.	0.506
C2cd4a	Snap23	ENSMAUP00000001770	ENSMAUP00000011076	C2 calcium-dependent domain-containing protein 4A.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.611
C2cd4a	Snap25	ENSMAUP00000001770	ENSMAUP00000025130	C2 calcium-dependent domain-containing protein 4A.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.611
C2cd4a	Snap47	ENSMAUP00000001770	ENSMAUP00000022636	C2 calcium-dependent domain-containing protein 4A.	Synaptosomal-associated protein 47 isoform X1.	0.611
C2cd4a	Stx11	ENSMAUP00000001770	ENSMAUP00000002512	C2 calcium-dependent domain-containing protein 4A.	Syntaxin-11; Belongs to the syntaxin family.	0.615
C2cd4a	Stx19	ENSMAUP00000001770	ENSMAUP00000003768	C2 calcium-dependent domain-containing protein 4A.	Syntaxin-19; Belongs to the syntaxin family.	0.603

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