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Ugt2a3 Ugt2a3 Cyp26b1 Cyp26b1 Cyp26a1 Cyp26a1 Cyp2c70 Cyp2c70 Cyp1a2 Cyp1a2 Cyp3a13 Cyp3a13 LOC101836914 LOC101836914 Aldh1a2 Aldh1a2 Cyp2s1 Cyp2s1 Ugt2b1 Ugt2b1 Cyp26c1 Cyp26c1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ugt2a3UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa)
Cyp26b1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
Cyp26a1Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa)
Cyp2c70Cytochrome P450 2C70-like; Belongs to the cytochrome P450 family. (489 aa)
Cyp1a2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (513 aa)
Cyp3a13Cytochrome P450 3A9. (503 aa)
LOC101836914Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (473 aa)
Aldh1a2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
Cyp2s1Cytochrome P450 2S1 isoform X1; Belongs to the cytochrome P450 family. (500 aa)
Ugt2b1UDP-glucuronosyltransferase 2B1; Belongs to the UDP-glycosyltransferase family. (530 aa)
Cyp26c1Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (516 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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