80 items (Mesocricetus auratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Stau1	Double-stranded RNA-binding protein Staufen homolog 1 isoform X2. (495 aa)
	Ilf2	Interleukin enhancer-binding factor 2. (390 aa)
	ENSMAUP00000014169	annotation not available (217 aa)
	Eif4h	Eukaryotic translation initiation factor 4H. (148 aa)
	Dgcr8	Microprocessor complex subunit DGCR8 isoform X2. (773 aa)
	Eif2ak2	Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (517 aa)
	Oas3	2'-5'-oligoadenylate synthase 3 isoform X2. (131 aa)
	Rftn2	Raftlin-2. (498 aa)
	Sidt2	SID1 transmembrane family member 2 isoform X1. (853 aa)
	Oas1	2'-5'-oligoadenylate synthase 1 isoform X2. (39 aa)
	Ago1	Protein argonaute-1 isoform X1; Belongs to the argonaute family. (857 aa)
	Adar	Double-stranded RNA-specific adenosine deaminase isoform X3. (925 aa)
	Strbp	Spermatid perinuclear RNA-binding protein isoform X1. (672 aa)
	Ddx1	ATP-dependent RNA helicase DDX1. (455 aa)
	Zfr2	Zinc finger RNA binding protein 2. (730 aa)
	Ddx60	Probable ATP-dependent RNA helicase DDX60. (1708 aa)
	LOC101822825	2'-5'-oligoadenylate synthase-like protein 1. (296 aa)
	Oas2	2'-5'-oligoadenylate synthase 2 isoform X1. (725 aa)
	Znf346	Zinc finger protein 346 isoform X2. (294 aa)
	Ago3	Protein argonaute-4-like. (754 aa)
	LOC106021236	LOW QUALITY PROTEIN: 60 kDa heat shock protein, mitochondrial-like; Belongs to the chaperonin (HSP60) family. (569 aa)
	Tlr7	Toll-like receptor 7 isoform X1; Belongs to the Toll-like receptor family. (1050 aa)
	Hspd1	60 kDa heat shock protein, mitochondrial. (387 aa)
	Adad1	Adenosine deaminase domain-containing protein 1 isoform X1. (618 aa)
	Eif4b	Eukaryotic translation initiation factor 4B. (599 aa)
	Tfrc	Transferrin receptor protein 1. (757 aa)
	Msn	Moesin. (579 aa)
	Aptx	Aprataxin isoform X1. (340 aa)
	Supv3l1	ATP-dependent RNA helicase SUPV3L1, mitochondrial isoform X1. (778 aa)
	Tubb4b	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
	Ago2	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (820 aa)
	Hnrnpu	Heterogeneous nuclear ribonucleoprotein U. (813 aa)
	LOC101829188-2	2'-5'-oligoadenylate synthase-like protein 2. (239 aa)
	Eif4a1	Eukaryotic translation initiation factor 4A1. (212 aa)
	ENSMAUP00000007509	annotation not available (458 aa)
	Adarb1	Double-stranded RNA-specific editase 1 isoform X4. (711 aa)
	Adad2	Adenosine deaminase domain-containing protein 2 isoform X1. (564 aa)
	Sidt1	SID1 transmembrane family member 1 isoform X1. (832 aa)
	ENSMAUP00000021721	annotation not available (153 aa)
	Prkra	Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1. (313 aa)
	Tarbp2	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (365 aa)
	Dhx58	Probable ATP-dependent RNA helicase DHX58. (678 aa)
	Ilf3	Interleukin enhancer-binding factor 3 isoform X3. (896 aa)
	Ddx58	Putative ATP-dependent RNA helicase DDX58. (908 aa)
	Ago4	Protein argonaute-4. (774 aa)
	LOC101823672	2'-5'-oligoadenylate synthase 1A-like. (157 aa)
	Stau2	Double-stranded RNA-binding protein Staufen homolog 2. (491 aa)
	Dhx30	Putative ATP-dependent RNA helicase DHX30. (1222 aa)
	Tlr3	Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
	Nlrp6	NACHT, LRR and PYD domains-containing protein 6 isoform X2. (896 aa)
	Rc3h1	Roquin-1. (1059 aa)
	Dhx36	ATP-dependent RNA helicase DHX36. (999 aa)
	Dhx9	ATP-dependent RNA helicase A. (1386 aa)
	Myh4	Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1732 aa)
	Elavl1	ELAV-like protein; Belongs to the RRM elav family. (326 aa)
	LOC101829188	2'-5'-oligoadenylate synthase-like protein 2. (101 aa)
	Zfr	Zinc finger RNA-binding protein isoform X2. (1077 aa)
	Mtdh	Protein LYRIC. (581 aa)
	Zbp1	Z-DNA-binding protein 1 isoform X1. (407 aa)
	LOC106021986	2'-5'-oligoadenylate synthase 1A-like. (280 aa)
	Drosha	Ribonuclease 3 isoform X5. (1375 aa)
	Rc3h2	Roquin-2. (1013 aa)
	LOC101825458	Alpha-actinin-4. (692 aa)
	Yrdc	yrdC domain-containing protein, mitochondrial. (105 aa)
	Mbnl1	Muscleblind-like protein 1 isoform X2. (387 aa)
	Tlr8	Toll-like receptor 8 isoform X1; Belongs to the Toll-like receptor family. (1028 aa)
	Rftn1	Raftlin. (547 aa)
	Vim	Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. (466 aa)
	Cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
	Dicer1	Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1917 aa)
	Adarb2	Double-stranded RNA-specific editase B2. (745 aa)
	Dhx33	Putative ATP-dependent RNA helicase DHX33. (698 aa)
	LOC106021992	2'-5'-oligoadenylate synthase 1A-like. (296 aa)
	Lsm14a	Protein LSM14 homolog A. (413 aa)
	Ddx21	Nucleolar RNA helicase 2. (793 aa)
	Dhx15	pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 isoform X1. (795 aa)
	Mrpl44	39S ribosomal protein L44, mitochondrial. (332 aa)
	Slc3a2	Solute carrier family 3 member 2. (113 aa)
	Slc3a2-2	4F2 cell-surface antigen heavy chain isoform X1. (157 aa)
	Prkrip1	PRKR-interacting protein 1. (185 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adar	Ago2	ENSMAUP00000016763	ENSMAUP00000005729	Double-stranded RNA-specific adenosine deaminase isoform X3.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.517
Adar	Ddx58	ENSMAUP00000016763	ENSMAUP00000025205	Double-stranded RNA-specific adenosine deaminase isoform X3.	Putative ATP-dependent RNA helicase DDX58.	0.436
Adar	Dhx58	ENSMAUP00000016763	ENSMAUP00000022537	Double-stranded RNA-specific adenosine deaminase isoform X3.	Probable ATP-dependent RNA helicase DHX58.	0.437
Adar	Dhx9	ENSMAUP00000016763	ENSMAUP00000023228	Double-stranded RNA-specific adenosine deaminase isoform X3.	ATP-dependent RNA helicase A.	0.679
Adar	Dicer1	ENSMAUP00000016763	ENSMAUP00000008586	Double-stranded RNA-specific adenosine deaminase isoform X3.	Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily.	0.702
Adar	Drosha	ENSMAUP00000016763	ENSMAUP00000002953	Double-stranded RNA-specific adenosine deaminase isoform X3.	Ribonuclease 3 isoform X5.	0.513
Adar	Eif2ak2	ENSMAUP00000016763	ENSMAUP00000000344	Double-stranded RNA-specific adenosine deaminase isoform X3.	Interferon-induced, double-stranded RNA-activated protein kinase isoform X1.	0.742
Adar	Elavl1	ENSMAUP00000016763	ENSMAUP00000001239	Double-stranded RNA-specific adenosine deaminase isoform X3.	ELAV-like protein; Belongs to the RRM elav family.	0.412
Adar	Ilf3	ENSMAUP00000016763	ENSMAUP00000023207	Double-stranded RNA-specific adenosine deaminase isoform X3.	Interleukin enhancer-binding factor 3 isoform X3.	0.529
Adar	Oas3	ENSMAUP00000016763	ENSMAUP00000014175	Double-stranded RNA-specific adenosine deaminase isoform X3.	2'-5'-oligoadenylate synthase 3 isoform X2.	0.405
Adar	Stau1	ENSMAUP00000016763	ENSMAUP00000013959	Double-stranded RNA-specific adenosine deaminase isoform X3.	Double-stranded RNA-binding protein Staufen homolog 1 isoform X2.	0.478
Adar	Zbp1	ENSMAUP00000016763	ENSMAUP00000001471	Double-stranded RNA-specific adenosine deaminase isoform X3.	Z-DNA-binding protein 1 isoform X1.	0.425
Adarb1	Dicer1	ENSMAUP00000007768	ENSMAUP00000008586	Double-stranded RNA-specific editase 1 isoform X4.	Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily.	0.404
Adarb1	Drosha	ENSMAUP00000007768	ENSMAUP00000002953	Double-stranded RNA-specific editase 1 isoform X4.	Ribonuclease 3 isoform X5.	0.464
Adarb1	Eif2ak2	ENSMAUP00000007768	ENSMAUP00000000344	Double-stranded RNA-specific editase 1 isoform X4.	Interferon-induced, double-stranded RNA-activated protein kinase isoform X1.	0.414
Adarb1	Prkra	ENSMAUP00000007768	ENSMAUP00000022086	Double-stranded RNA-specific editase 1 isoform X4.	Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1.	0.539
Adarb1	Stau1	ENSMAUP00000007768	ENSMAUP00000013959	Double-stranded RNA-specific editase 1 isoform X4.	Double-stranded RNA-binding protein Staufen homolog 1 isoform X2.	0.465
Adarb1	Tarbp2	ENSMAUP00000007768	ENSMAUP00000022342	Double-stranded RNA-specific editase 1 isoform X4.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.502
Adarb2	Dicer1	ENSMAUP00000009096	ENSMAUP00000008586	Double-stranded RNA-specific editase B2.	Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily.	0.404
Adarb2	Drosha	ENSMAUP00000009096	ENSMAUP00000002953	Double-stranded RNA-specific editase B2.	Ribonuclease 3 isoform X5.	0.464

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