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| | ENSMAUP00000002290 | annotation not available (209 aa) |
| | LOC101843716 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (493 aa) |
| | Cyp26b1 | Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa) |
| | Ces1e | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | Adh5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (343 aa) |
| | Aldh1a3 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | Plpp6 | Phospholipid phosphatase 6. (290 aa) |
| | ADH1 | Alcohol dehydrogenase 1. (361 aa) |
| | Cyp26a1 | Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa) |
| | Srd5a3 | Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5- alpha-dihydrotestosterone (DHT) (By similarity). (328 aa) |
| | Aldh1a2 | Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa) |
| | Rdh14 | Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa) |
| | Dpm1 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa) |
| | Rarres2 | Retinoic acid receptor responder protein 2 isoform X2. (163 aa) |
| | Dhrs13 | Dehydrogenase/reductase SDR family member 13. (377 aa) |
| | Crh | Corticoliberin. (187 aa) |
| | LOC101830355 | Retinol dehydrogenase 7-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (211 aa) |
| | Idi1 | Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (227 aa) |
| | Rdh11 | Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | Nus1 | Dehydrodolichyl diphosphate synthase complex subunit NUS1. (291 aa) |
| | LOC101844358 | Liver carboxylesterase; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. (560 aa) |
| | Awat2 | acyl-CoA wax alcohol acyltransferase 2. (333 aa) |
| | Ppard | Peroxisome proliferator-activated receptor delta isoform X1. (440 aa) |
| | Dhdds | Alkyl transferase; Belongs to the UPP synthase family. (334 aa) |
| | Lipe | Hormone-sensitive lipase isoform X1. (1060 aa) |
| | Dgat1 | O-acyltransferase. (498 aa) |
| | Lss | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa) |
| | Retsat | All-trans-retinol 13,14-reductase. (609 aa) |
| | ENSMAUP00000004824 | annotation not available (194 aa) |
| | LOC101832144 | Cytochrome P450 2C28; Catalyzes the N-demethylation of aminopyrine and benzphetamine, but does not catalyze the hydroxylation of tolbutamide, testosterone, and progesterone; Belongs to the cytochrome P450 family. (490 aa) |
| | ENSMAUP00000004882 | annotation not available (294 aa) |
| | Pdss2 | Decaprenyl-diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family. (423 aa) |
| | Rdh8 | Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | Bco2 | Beta,beta-carotene 9',10'-oxygenase isoform X1. (532 aa) |
| | Rbp2 | Retinol-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (84 aa) |
| | Adh4 | Alcohol dehydrogenase 4. (377 aa) |
| | Dpagt1 | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase isoform X1. (408 aa) |
| | Lrat | Lecithin retinol acyltransferase. (231 aa) |
| | Egfr | Receptor protein-tyrosine kinase. (1207 aa) |
| | Rdh12 | Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | Akr1e2 | 1,5-anhydro-D-fructose reductase. (301 aa) |
| | Rbp1 | LOW QUALITY PROTEIN: retinol-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | Sdr16c5 | Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (199 aa) |
| | Sdr9c7 | Short-chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa) |
| | Adh6a | Alcohol dehydrogenase 1-like. (375 aa) |
| | Bco1 | Beta,beta-carotene 15,15'-dioxygenase. (555 aa) |
| | Rdh13 | Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa) |
| | Dpm2 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (53 aa) |
| | LOC101823051 | Alcohol dehydrogenase 1 isoform X2. (362 aa) |
| | Gm4756 | Dehydrogenase/reductase SDR family member 7 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | Cyp1a2 | Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (513 aa) |
| | Pmvk | Phosphomevalonate kinase. (119 aa) |
| | Akr1b1 | Aldose reductase. (316 aa) |
| | Pecr | Peroxisomal trans-2-enoyl-CoA reductase. (275 aa) |
| | Rpe65 | Retinoid isomerohydrolase. (533 aa) |
| | Dgat2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | Aldh1a1 | Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity). (513 aa) |
| | Dhrs7 | Dehydrogenase/reductase SDR family member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (228 aa) |
| | Ttr | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa) |
| | Akr1b8 | Aldo-keto reductase family 1 member B10. (302 aa) |
| | Mvk | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | Htra2 | Serine protease HTRA2, mitochondrial. (458 aa) |
| | LOC101838830 | LOW QUALITY PROTEIN: cytochrome P450 2D20-like; Belongs to the cytochrome P450 family. (476 aa) |
| | Hmgcr | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. (887 aa) |
| | Cyp1a1 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (507 aa) |
| | Cyp1b1 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (541 aa) |
| | Cel | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (599 aa) |
| | Coq2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (211 aa) |
| | Dhrs4 | Dehydrogenase/reductase SDR family member 4. (279 aa) |
| | Abca4 | Retinal-specific ATP-binding cassette transporter. (1991 aa) |
| | Coq2-2 | Coenzyme Q2, polyprenyltransferase. (44 aa) |
| | Pnlip | Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa) |
| | Rusc2 | Iporin. (1493 aa) |
| | Aldh8a1 | Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family. (488 aa) |
| | Crppa | Isoprenoid synthase domain-containing protein isoform X1. (443 aa) |
| | Dhrs3 | Short-chain dehydrogenase/reductase 3 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | Pdss1 | Decaprenyl-diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. (407 aa) |
| | Hmgcs1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa) |
| | Hmgcs2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | Rdh10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | Mvd | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (401 aa) |
| | Crabp2 | Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | Fdft1 | Squalene synthase. (417 aa) |
| | Rbp4 | Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa) |
| | Srd5a1 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa) |
| | Cyp2w1 | Cytochrome P450 2W1; Belongs to the cytochrome P450 family. (493 aa) |
| | Phyh | phytanoyl-CoA dioxygenase, peroxisomal. (338 aa) |
| | Cyp26c1 | Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (516 aa) |
| | Dhrs9 | Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa) |
| | Cyp2s1 | Cytochrome P450 2S1 isoform X1; Belongs to the cytochrome P450 family. (500 aa) |
| | Sdr16c6 | Short-chain dehydrogenase/reductase family 16C member 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | Th | Tyrosine 3-monooxygenase. (498 aa) |
| | Crabp1 | Cellular retinoic acid binding protein I; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa) |
| | Aldh3a2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa) |
| | LOC101841000 | Isopentenyl-diphosphate delta-isomerase 2. (156 aa) |
| | Plb1 | Phospholipase B1, membrane-associated. (1446 aa) |
| | Pnpla2 | Patatin-like phospholipase domain-containing protein 2. (486 aa) |
