STRINGSTRING
Mapk10 Mapk10 Nox1 Nox1 Stk3 Stk3 Irak4 Irak4 Map3k11 Map3k11 Wnt5a Wnt5a Tnf Tnf Ptger4 Ptger4 Lrrk2 Lrrk2 Gadd45a Gadd45a LOC101825816 LOC101825816 Map3k13 Map3k13 Mapk8ip3 Mapk8ip3 Mapk8ip2 Mapk8ip2 Myd88 Myd88 Trib1 Trib1 Ripk2 Ripk2 Nod1 Nod1 Pafah1b1 Pafah1b1 Tnfsf11 Tnfsf11 Nphs1 Nphs1 Ror2 Ror2 Irak1 Irak1 Stradb Stradb Map2k7 Map2k7 Hacd3 Hacd3 Nod2 Nod2 Traf6 Traf6 Mapk8ip1 Mapk8ip1 Mapk8 Mapk8 Map3k1 Map3k1 Ercc6 Ercc6 Smad3 Smad3 Map3k20 Map3k20 Tlr3 Tlr3 Card9 Card9 Map4k1 Map4k1 Daxx Daxx Map3k12 Map3k12 Gps2 Gps2 Atf2 Atf2 Cdc42ep5 Cdc42ep5 Map3k5 Map3k5 Nfkb1 Nfkb1 Tlr7 Tlr7 Dusp19 Dusp19 Mapk9 Mapk9 Tlr4 Tlr4 Map3k7 Map3k7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Nox1NADPH oxidase 1. (587 aa)
Stk3Serine/threonine-protein kinase 3. (468 aa)
Irak4Interleukin-1 receptor-associated kinase 4. (461 aa)
Map3k11Mitogen-activated protein kinase kinase kinase 11. (265 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
Ptger4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (488 aa)
Lrrk2Leucine-rich repeat serine/threonine-protein kinase 2. (2527 aa)
Gadd45aGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)
LOC101825816STE20-related kinase adapter protein beta. (172 aa)
Map3k13Mitogen-activated protein kinase kinase kinase 13. (560 aa)
Mapk8ip3C-Jun-amino-terminal kinase-interacting protein 3. (1337 aa)
Mapk8ip2C-Jun-amino-terminal kinase-interacting protein 2. (830 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
Trib1Tribbles homolog 1 isoform X1. (373 aa)
Ripk2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (325 aa)
Nod1Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (953 aa)
Pafah1b1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (349 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member. (318 aa)
Nphs1Nephrin isoform X1. (1256 aa)
Ror2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (922 aa)
Irak1Interleukin-1 receptor-associated kinase 1 isoform X2. (747 aa)
StradbSTE20-related kinase adapter protein beta. (280 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (520 aa)
Hacd3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2 isoform X2. (1023 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
Mapk8ip1C-Jun-amino-terminal kinase-interacting protein 1 isoform X1. (698 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1475 aa)
Ercc6DNA excision repair protein ERCC-6. (1236 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
Map3k20Mitogen-activated protein kinase kinase kinase 20. (762 aa)
Tlr3Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
Card9Caspase recruitment domain-containing protein 9 isoform X2. (537 aa)
Map4k1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (743 aa)
DaxxDeath domain-associated protein 6 isoform X1. (131 aa)
Map3k12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (877 aa)
Gps2G protein pathway suppressor 2 isoform X2. (327 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
Cdc42ep5Cdc42 effector protein 5. (153 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1381 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa)
Tlr7Toll-like receptor 7 isoform X1; Belongs to the Toll-like receptor family. (1050 aa)
Dusp19Dual specificity protein phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (141 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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