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| | Hsd17b11 | Estradiol 17-beta-dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa) |
| | Nsdhl | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (362 aa) |
| | Pctp | Phosphatidylcholine transfer protein isoform X2. (214 aa) |
| | Cyp27b1 | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa) |
| | Smpd1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa) |
| | Amacr | alpha-methylacyl-CoA racemase isoform X1. (382 aa) |
| | LOC101843667 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa) |
| | Sdr9c7 | Short-chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa) |
| | LOC101843592 | Acyl-coenzyme A thioesterase 6-like isoform X1. (261 aa) |
| | LOC101843125 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (389 aa) |
| | Angptl3 | Angiopoietin-related protein 3. (460 aa) |
| | Prkaa2 | Non-specific serine/threonine protein kinase. (542 aa) |
| | Lepr | Leptin receptor. (1113 aa) |
| | Lss | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa) |
| | Lipe | Hormone-sensitive lipase isoform X1. (1060 aa) |
| | Cyp8b1 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (501 aa) |
| | Gba | Glucosylceramidase. (515 aa) |
| | Lipa | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa) |
| | Sqle | Squalene monooxygenase. (573 aa) |
| | LOC101843587 | Aldo-keto reductase family 1 member C21-like isoform X1. (319 aa) |
| | LOC101843034 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa) |
| | Cebpa | CCAAT/enhancer-binding protein alpha. (364 aa) |
| | Sult1e1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa) |
| | LOC101841267 | prostaglandin-E(2) 9-reductase-like isoform X2. (311 aa) |
| | Cyp26a1 | Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa) |
| | Hsd17b1 | Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa) |
| | LOC101842056 | UDP-glucuronosyltransferase 2A2; Belongs to the UDP-glycosyltransferase family. (692 aa) |
| | G6pc | Glucose-6-phosphatase. (320 aa) |
| | App | Amyloid beta A4 protein. (751 aa) |
| | LOC101839651 | Aldo-keto reductase family 1 member C21-like. (310 aa) |
| | Fech | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (422 aa) |
| | ENSMAUP00000002290 | annotation not available (209 aa) |
| | Ywhah | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta. (176 aa) |
| | LOC101843716 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (493 aa) |
| | Cyp26b1 | Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa) |
| | LOC101835654 | Signal transducer and activator of transcription. (228 aa) |
| | Ces1e | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | Ch25h | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (284 aa) |
| | Sdr42e1 | Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family. (393 aa) |
| | Abcb11 | Bile salt export pump. (1061 aa) |
| | LOC101843930 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa) |
| | Prkaa1 | Non-specific serine/threonine protein kinase. (522 aa) |
| | LOC101831195 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa) |
| | Bdh1 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. (331 aa) |
| | Insig1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (262 aa) |
| | LOC106021445 | L-xylulose reductase-like isoform X1. (163 aa) |
| | Ccdc160 | Coiled-coil domain-containing protein 160 isoform X2. (323 aa) |
| | Vldlr | Very low-density lipoprotein receptor isoform X1. (510 aa) |
| | Fabp6 | Gastrotropin. (128 aa) |
| | Chst10 | Carbohydrate sulfotransferase. (356 aa) |
| | LOC101822554 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa) |
| | Mt3 | Metallothionein 3. (68 aa) |
| | Hmgcs1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa) |
| | Srd5a1 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa) |
| | Lep | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | LOC101844449 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (288 aa) |
| | ENSMAUP00000023469 | annotation not available (143 aa) |
| | Scap | Sterol regulatory element-binding protein cleavage-activating protein. (1275 aa) |
| | Sult4a1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (267 aa) |
| | Mbtps1 | Membrane-bound transcription factor site-1 protease isoform X1. (1052 aa) |
| | Gc | Vitamin D-binding protein. (485 aa) |
| | Scp2 | Non-specific lipid-transfer protein isoform X2; Belongs to the thiolase-like superfamily. Thiolase family. (231 aa) |
| | Apoc1 | Apolipoprotein C-I. (88 aa) |
| | Nfe2l1 | Nuclear factor erythroid 2-related factor 1 isoform X1. (770 aa) |
| | Tmem130 | Transmembrane protein 130. (424 aa) |
| | Cyp7b1 | 25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (509 aa) |
| | Fdft1 | Squalene synthase. (417 aa) |
| | Mvd | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (401 aa) |
| | Nr3c1 | Glucocorticoid receptor isoform X2. (382 aa) |
| | Apoc3 | Apolipoprotein C-III. (53 aa) |
| | Ugt2b1 | UDP-glucuronosyltransferase 2B1; Belongs to the UDP-glycosyltransferase family. (530 aa) |
| | Hmgcs2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | Stard4 | stAR-related lipid transfer protein 4. (169 aa) |
| | Tspo | Translocator protein. (169 aa) |
| | Cyp21a1 | Steroid 21-hydroxylase isoform X2; Belongs to the cytochrome P450 family. (496 aa) |
| | Gm12248 | Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family. (343 aa) |
| | Arv1 | Protein ARV1 isoform X1. (266 aa) |
| | Dhrs9 | Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa) |
| | Stard3 | stAR-related lipid transfer protein 3. (442 aa) |
| | G6pc2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa) |
| | Fdx1 | Adrenodoxin, mitochondrial. (188 aa) |
| | Pcsk9 | Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (676 aa) |
| | Hsd17b7 | 3-keto-steroid reductase. (347 aa) |
| | Acaa1 | 3-ketoacyl-CoA thiolase, peroxisomal. (230 aa) |
| | LOC101842245 | Aldo-keto reductase family 1 member C13-like isoform X1. (311 aa) |
| | Hnf1a | Hepatocyte nuclear factor 1-alpha isoform X2. (630 aa) |
| | Rdh8 | Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | Cyp2r1 | Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family. (501 aa) |
| | Cyp26c1 | Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (516 aa) |
| | Sult2b1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (371 aa) |
| | Apoa5 | Apolipoprotein A-V. (363 aa) |
| | LOC101844897 | UDP-glucuronosyltransferase 2B4-like. (462 aa) |
| | LOC101841000 | Isopentenyl-diphosphate delta-isomerase 2. (156 aa) |
| | Hsd11b2 | Corticosteroid 11-beta-dehydrogenase isozyme 2. (401 aa) |
| | Fdxr | NADPH:adrenodoxin oxidoreductase, mitochondrial. (493 aa) |
| | Gba2 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (917 aa) |
| | Pdgfra | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | Cyb5r3 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (342 aa) |
| | Ldlrap1 | Low density lipoprotein receptor adapter protein 1. (307 aa) |
| | Hsd17b3 | Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (217 aa) |
| | Scd1 | acyl-CoA desaturase 1-like. (212 aa) |
| | Apoa4 | Apolipoprotein A-IV. (267 aa) |
| | Enpp1 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1. (906 aa) |
| | Med1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1576 aa) |
| | Ldlr | Low-density lipoprotein receptor isoform X1. (856 aa) |
| | Mecp2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa) |
| | Fgfr1 | Fibroblast growth factor receptor. (819 aa) |
| | Spp1 | Osteopontin precursor. (305 aa) |
| | Apoa1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (264 aa) |
| | Lrp5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa) |
| | LOC101843311 | 3-hydroxyhexobarbital dehydrogenase 1/3-alpha, 17-beta-hydroxysteroid dehydrogenase. (323 aa) |
| | Dhcr7 | 7-dehydrocholesterol reductase. (471 aa) |
| | Akr1c14 | 3-alpha-hydroxysteroid dehydrogenase-like isoform X1. (323 aa) |
| | Hdlbp | Vigilin. (1268 aa) |
| | Hsd17b2 | Estradiol 17-beta-dehydrogenase 2 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (283 aa) |
| | Cacna1h | Voltage-dependent T-type calcium channel subunit alpha-1H isoform X3. (147 aa) |
| | Star | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity). (284 aa) |
| | Cetp | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (494 aa) |
| | Apof | LOW QUALITY PROTEIN: apolipoprotein F. (314 aa) |
| | Tecr | Very-long-chain enoyl-CoA reductase isoform X1. (313 aa) |
| | Idi1 | Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (227 aa) |
| | Slc27a2 | Very long-chain acyl-CoA synthetase. (620 aa) |
| | Srd5a2 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (253 aa) |
| | LOC101830355 | Retinol dehydrogenase 7-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (211 aa) |
| | Crh | Corticoliberin. (187 aa) |
| | Akr1c18 | Aldo-keto reductase family 1 member C18 isoform X1. (323 aa) |
| | Pon1 | Serum paraoxonase/arylesterase 1. (355 aa) |
| | Shh | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (439 aa) |
| | Apoa2 | Apolipoprotein A-II. (101 aa) |
| | Ptgis | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (493 aa) |
| | Soat2 | O-acyltransferase. (521 aa) |
| | Srebf1 | Sterol regulatory element-binding protein 1 isoform X1. (1130 aa) |
| | Apoe | Apolipoprotein E. (314 aa) |
| | Ebp | EBP cholestenol delta-isomerase. (156 aa) |
| | Pex2 | Peroxisome biogenesis factor 2. (305 aa) |
| | Cubn | Cubilin. (2791 aa) |
| | Cyb5r1 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa) |
| | Akr1c19 | Aldo-keto reductase family 1 member C13-like. (251 aa) |
| | Cyp17a1 | Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (431 aa) |
| | Slc37a4 | Glucose-6-phosphate exchanger SLC37A4 isoform X2. (429 aa) |
| | Ces1d | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | Cyp39a1 | 24-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (377 aa) |
| | Srebf2 | Sterol regulatory element-binding protein 2. (958 aa) |
| | Ednrb | Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa) |
| | Tm7sf2 | Delta(14)-sterol reductase isoform X1. (418 aa) |
| | Cyp19a1 | Aromatase; Belongs to the cytochrome P450 family. (503 aa) |
| | Npc1l1 | Niemann-Pick C1-like protein 1 precursor. (712 aa) |
| | Cyb5r2 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (292 aa) |
| | Sc5d | Lathosterol oxidase; Belongs to the sterol desaturase family. (299 aa) |
| | Tsku | Tsukushin. (354 aa) |
| | Abca1 | ATP-binding cassette sub-family A member 1 isoform X2. (2261 aa) |
| | Erlin2 | Erlin-2. (339 aa) |
| | LOC101826047 | Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (200 aa) |
| | LOC101832654 | Carboxylesterase 1C-like. (426 aa) |
| | Abcd3 | ATP-binding cassette sub-family D member 3. (659 aa) |
| | Cftr | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1184 aa) |
| | LOC101823629 | 3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase. (203 aa) |
| | Gm5737 | Putative short-chain dehydrogenase/reductase family 42E member 2. (423 aa) |
| | Lipc | Hepatic triacylglycerol lipase isoform X2. (538 aa) |
| | LOC101837099 | NADPH-dependent 3-keto-steroid reductase HSD3B3; Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Does not function as an isomerase. Belongs to the 3-beta-HSD family. (373 aa) |
| | Cyp46a1 | Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa) |
| | Afp | Alpha-fetoprotein. (609 aa) |
| | Dhrs4 | Dehydrogenase/reductase SDR family member 4. (279 aa) |
| | Hsd17b8 | Estradiol 17-beta-dehydrogenase 8. (259 aa) |
| | Aplp2 | Amyloid-like protein 2 isoform X1. (759 aa) |
| | Comt | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (264 aa) |
| | Cyp24a1 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa) |
| | Tiparp | TCDD-inducible poly [ADP-ribose] polymerase. (657 aa) |
| | Lbr | lamin-B receptor. (619 aa) |
| | Hsd17b10 | 3-hydroxyacyl-CoA dehydrogenase type-2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | Cyp1b1 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (541 aa) |
| | Cyp1a1 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (507 aa) |
| | Cat | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | LOC101823339 | Cytochrome P450 11B1, mitochondrial; A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) [...] (319 aa) |
| | LOC101827747 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa) |
| | Cln8 | Protein CLN8. (124 aa) |
| | Hmgcr | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins; Belongs to the HMG-CoA reductase family. (887 aa) |
| | LOC101838830 | LOW QUALITY PROTEIN: cytochrome P450 2D20-like; Belongs to the cytochrome P450 family. (476 aa) |
| | Hsd11b1 | Corticosteroid 11-beta-dehydrogenase isozyme 1; Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta- hydroxycholesterol; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa) |
| | Cyp27a1 | Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (534 aa) |
| | Msmo1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa) |
| | Tnfsf4 | Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (192 aa) |
| | Mvk | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | Hsd17b12 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa) |
| | Cyp7a1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | Insig2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | Erg28 | Probable ergosterol biosynthetic protein 28. (140 aa) |
| | Pip4p1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | Fgfr4 | Fibroblast growth factor receptor. (794 aa) |
| | Lima1 | LIM domain and actin-binding protein 1. (749 aa) |
| | Dhrs11 | Dehydrogenase/reductase SDR family member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa) |
| | Hsdl1 | Inactive hydroxysteroid dehydrogenase-like protein 1. (330 aa) |
| | Akr1d1 | 3-oxo-5-beta-steroid 4-dehydrogenase. (325 aa) |
| | Sult1a1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (250 aa) |
| | Nr1h4 | Farnesoid-X-receptor beta splice variant 2. (487 aa) |
| | Hsd17b4 | Peroxisomal multifunctional enzyme type 2. (705 aa) |
| | Slc27a5 | Bile acyl-CoA synthetase. (690 aa) |
| | Abca5 | ATP-binding cassette sub-family A member 5 isoform X1. (1642 aa) |
| | Apob | Apolipoprotein B-100. (4488 aa) |
| | Abcg1 | ATP-binding cassette sub-family G member 1 isoform X1. (666 aa) |
| | Adm | ADM. (177 aa) |
| | Dhcr24 | Delta(24)-sterol reductase. (516 aa) |
| | Cyp3a13 | Cytochrome P450 3A9. (503 aa) |
| | Cln6 | Ceroid-lipofuscinosis neuronal protein 6 isoform X1. (308 aa) |
| | Baat | Bile acid-CoA:amino acid N-acyltransferase. (419 aa) |
| | Il4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (147 aa) |
| | Lrp1 | Prolow-density lipoprotein receptor-related protein 1. (4017 aa) |
| | Pmvk | Phosphomevalonate kinase. (119 aa) |
| | Fgf23 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa) |
| | Cyp1a2 | Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (513 aa) |
| | Scarb1 | Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (509 aa) |
| | Lcat | Phosphatidylcholine-sterol acyltransferase. (248 aa) |
| | Hsd3b7 | 3 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family. (369 aa) |
| | Ces1g | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | Scp2d1 | SCP2 sterol-binding domain-containing protein 1 isoform X1. (156 aa) |
| | Nr5a2 | Nuclear receptor subfamily 5 group A member 2 isoform X2. (136 aa) |
| | Sgpl1 | Sphingosine-1-phosphate lyase 1. (568 aa) |
| | Soat1 | O-acyltransferase. (546 aa) |
| | Apon | Uncharacterized LOC101832433. (233 aa) |
| | Plekha1 | Pleckstrin homology domain-containing family A member 1 isoform X3. (383 aa) |
| | G6pd | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa) |
| | Acbd3 | Golgi resident protein GCP60. (525 aa) |
| | Atp8b1 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1198 aa) |
| | Cdcp2 | CUB domain-containing protein 2. (421 aa) |
