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Sdr42e1 Sdr42e1 LOC101839651 LOC101839651 Hsd17b1 Hsd17b1 Srd5a3 Srd5a3 LOC101841267 LOC101841267 LOC101843587 LOC101843587 Sdr9c7 Sdr9c7 Nsdhl Nsdhl Hsd17b11 Hsd17b11 Hsd3b7 Hsd3b7 Hsd17b4 Hsd17b4 Akr1d1 Akr1d1 Dhrs11 Dhrs11 Hsd17b12 Hsd17b12 Akr1b8 Akr1b8 Hsd11b1 Hsd11b1 Hsd17b10 Hsd17b10 Hsd17b8 Hsd17b8 LOC101837099 LOC101837099 Gm5737 Gm5737 Akr1c19 Akr1c19 Akr1c18 Akr1c18 LOC101830355 LOC101830355 Srd5a2 Srd5a2 Hsd17b2 Hsd17b2 Akr1c14 Akr1c14 LOC101843311 LOC101843311 Hsd17b3 Hsd17b3 Hsd11b2 Hsd11b2 Rdh8 Rdh8 LOC101842245 LOC101842245 Srd5a1 Srd5a1 Hsd17b7 Hsd17b7 Dhrs9 Dhrs9 Hsd17b13 Hsd17b13 Bdh1 Bdh1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sdr42e1Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family. (393 aa)
LOC101839651Aldo-keto reductase family 1 member C21-like. (310 aa)
Hsd17b1Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
Srd5a3Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5- alpha-dihydrotestosterone (DHT) (By similarity). (328 aa)
LOC101841267prostaglandin-E(2) 9-reductase-like isoform X2. (311 aa)
LOC101843587Aldo-keto reductase family 1 member C21-like isoform X1. (319 aa)
Sdr9c7Short-chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
NsdhlSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (362 aa)
Hsd17b11Estradiol 17-beta-dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa)
Hsd3b73 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family. (369 aa)
Hsd17b4Peroxisomal multifunctional enzyme type 2. (705 aa)
Akr1d13-oxo-5-beta-steroid 4-dehydrogenase. (325 aa)
Dhrs11Dehydrogenase/reductase SDR family member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
Hsd17b12Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (253 aa)
Akr1b8Aldo-keto reductase family 1 member B10. (302 aa)
Hsd11b1Corticosteroid 11-beta-dehydrogenase isozyme 1; Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta- hydroxycholesterol; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
Hsd17b103-hydroxyacyl-CoA dehydrogenase type-2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
Hsd17b8Estradiol 17-beta-dehydrogenase 8. (259 aa)
LOC101837099NADPH-dependent 3-keto-steroid reductase HSD3B3; Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Does not function as an isomerase. Belongs to the 3-beta-HSD family. (373 aa)
Gm5737Putative short-chain dehydrogenase/reductase family 42E member 2. (423 aa)
Akr1c19Aldo-keto reductase family 1 member C13-like. (251 aa)
Akr1c18Aldo-keto reductase family 1 member C18 isoform X1. (323 aa)
LOC101830355Retinol dehydrogenase 7-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (211 aa)
Srd5a23-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (253 aa)
Hsd17b2Estradiol 17-beta-dehydrogenase 2 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (283 aa)
Akr1c143-alpha-hydroxysteroid dehydrogenase-like isoform X1. (323 aa)
LOC1018433113-hydroxyhexobarbital dehydrogenase 1/3-alpha, 17-beta-hydroxysteroid dehydrogenase. (323 aa)
Hsd17b3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (217 aa)
Hsd11b2Corticosteroid 11-beta-dehydrogenase isozyme 2. (401 aa)
Rdh8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
LOC101842245Aldo-keto reductase family 1 member C13-like isoform X1. (311 aa)
Srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
Hsd17b73-keto-steroid reductase. (347 aa)
Dhrs9Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
Hsd17b1317-beta-hydroxysteroid dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
Bdh1D-beta-hydroxybutyrate dehydrogenase, mitochondrial. (331 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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