STRINGSTRING
Rsbn1 Rsbn1 Plod3 Plod3 Sc5d Sc5d Cyp19a1 Cyp19a1 Cyp39a1 Cyp39a1 Egln2 Egln2 Ogfod1 Ogfod1 Cyp2u1 Cyp2u1 LOC101826326 LOC101826326 Cyp17a1 Cyp17a1 Akr1c19 Akr1c19 Riox2 Riox2 LOC101844759 LOC101844759 LOC101844221 LOC101844221 Degs1 Degs1 Ptgis Ptgis Scd2 Scd2 ENSMAUP00000017505 ENSMAUP00000017505 Nos2 Nos2 Tti2 Tti2 Akr1c18 Akr1c18 Phf2 Phf2 Cmah Cmah Nos1 Nos1 Nos3 Nos3 Tmem189 Tmem189 Jmjd4 Jmjd4 ENSMAUP00000018841 ENSMAUP00000018841 Crtap Crtap ENSMAUP00000019005 ENSMAUP00000019005 Cyp2s1 Cyp2s1 Kdm1b Kdm1b Akr1c14 Akr1c14 Phf8 Phf8 P3h4 P3h4 LOC101843311 LOC101843311 P4ha3 P4ha3 Fads6 Fads6 P4hb P4hb Kdm2a Kdm2a Moxd1 Moxd1 Pah Pah Phyhd1 Phyhd1 Th Th Tet3 Tet3 Scd1 Scd1 Ptgs2 Ptgs2 LOC101835628 LOC101835628 LOC106021304 LOC106021304 Kdm1a Kdm1a Fmo6 Fmo6 Hr Hr Jmjd8 Jmjd8 ENSMAUP00000021460 ENSMAUP00000021460 P3h3 P3h3 Alkbh4 Alkbh4 P3h2 P3h2 Cyp8b1 Cyp8b1 Sqle Sqle LOC101843587 LOC101843587 LOC101835264 LOC101835264 Fmo3 Fmo3 LOC101830700 LOC101830700 Saal1 Saal1 Plod2 Plod2 LOC101841267 LOC101841267 Cyp26a1 Cyp26a1 Tph1 Tph1 Cyp4f40 Cyp4f40 LOC101839651 LOC101839651 LOC101843716 LOC101843716 Cyp26b1 Cyp26b1 Ch25h Ch25h LOC101844487 LOC101844487 Kdm4c Kdm4c LOC101831088 LOC101831088 Degs2 Degs2 LOC101842758 LOC101842758 Riox1 Riox1 Fmo1 Fmo1 Scd3 Scd3 Hif1an Hif1an Cyp2r1 Cyp2r1 Egln1 Egln1 Cyp2t4 Cyp2t4 LOC101842245 LOC101842245 Cyp7b1 Cyp7b1 LOC101826941 LOC101826941 LOC101823450 LOC101823450 Fmo5 Fmo5 LOC101830378 LOC101830378 Plod1 Plod1 LOC101830438 LOC101830438 Cyp2j6 Cyp2j6 ENSMAUP00000024381 ENSMAUP00000024381 ENSMAUP00000024468 ENSMAUP00000024468 Kdm2b Kdm2b LOC101829291 LOC101829291 Ogfod2 Ogfod2 Cyp2w1 Cyp2w1 Asph Asph Cyp4f39 Cyp4f39 Cyp2g1 Cyp2g1 LOC101831527 LOC101831527 Phyh Phyh ENSMAUP00000024979 ENSMAUP00000024979 Pigs Pigs Cyp26c1 Cyp26c1 P3h1 P3h1 LOC101841752 LOC101841752 LOC101825889 LOC101825889 Tyr Tyr Ccdc160 Ccdc160 Hmox1 Hmox1 Micalcl Micalcl Kmo Kmo Fto Fto LOC101833813 LOC101833813 Coq7 Coq7 Agmo Agmo P4ha2 P4ha2 Tet1 Tet1 Mical1 Mical1 LOC101844281 LOC101844281 Kdm5b Kdm5b Ptgs1 Ptgs1 LOC101832144 LOC101832144 LOC101838830 LOC101838830 LOC101823194 LOC101823194 LOC101842021 LOC101842021 Cyp2f2 Cyp2f2 Gm12248 Gm12248 Cyp21a1 Cyp21a1 Tstd2 Tstd2 Kdm4b Kdm4b Alkbh8 Alkbh8 LOC101827747 LOC101827747 LOC101823339 LOC101823339 Kdm3a Kdm3a Bbox1 Bbox1 Cyp24a1 Cyp24a1 LOC101836914 LOC101836914 Pam Pam Cyp46a1 Cyp46a1 Cyp2ab1 Cyp2ab1 LOC101826047 LOC101826047 Cyp2c70 Cyp2c70 Alkbh1 Alkbh1 Cyp1a1 Cyp1a1 Fads2b Fads2b Cyp1b1 Cyp1b1 Fads2 Fads2 Mettl26 Mettl26 Kdm5a Kdm5a Alkbh5 Alkbh5 Dbh Dbh Kdm6b Kdm6b Fads1 Fads1 Gm4847 Gm4847 Fmo2 Fmo2 Cyp27b1 Cyp27b1 Dohh Dohh Ccndbp1 Ccndbp1 Kdm6a Kdm6a Mical2 Mical2 LOC101841191 LOC101841191 Cyp4f14 Cyp4f14 ENSMAUP00000007047 ENSMAUP00000007047 Cyp1a2 Cyp1a2 Tbxas1 Tbxas1 Cyp4f13 Cyp4f13 LOC101830103 LOC101830103 Pcbd1 Pcbd1 Alkbh2 Alkbh2 Tet2 Tet2 Tyw5 Tyw5 Fmo4 Fmo4 Cyp3a13 Cyp3a13 Hmox2 Hmox2 Kdm7a Kdm7a Fmo9 Fmo9 Cyp4a30b Cyp4a30b Kdm5c Kdm5c Mical3 Mical3 Kdm4d Kdm4d Por Por P4htm P4htm P4ha1 P4ha1 Coq6 Coq6 Jmjd6 Jmjd6 Akr1d1 Akr1d1 Kdm8 Kdm8 LOC101831958 LOC101831958 Cyp7a1 Cyp7a1 Tmlhe Tmlhe Cyp4b1 Cyp4b1 ENSMAUP00000011252 ENSMAUP00000011252 Cyp4x1 Cyp4x1 Tph2 Tph2 Kdm4a Kdm4a Msmo1 Msmo1 Ogfod3 Ogfod3 Egln3 Egln3 Cyp27a1 Cyp27a1 Fads3 Fads3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Rsbn1Round spermatid basic protein 1. (795 aa)
Plod3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (457 aa)
Sc5dLathosterol oxidase; Belongs to the sterol desaturase family. (299 aa)
Cyp19a1Aromatase; Belongs to the cytochrome P450 family. (503 aa)
Cyp39a124-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (377 aa)
Egln2Egl nine homolog 2. (125 aa)
Ogfod1Prolyl 3-hydroxylase OGFOD1. (545 aa)
Cyp2u1Cytochrome P450 2U1; Belongs to the cytochrome P450 family. (532 aa)
LOC101826326Cytochrome P450 2A9; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (493 aa)
Cyp17a1Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (431 aa)
Akr1c19Aldo-keto reductase family 1 member C13-like. (251 aa)
Riox2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (466 aa)
LOC101844759Cytochrome P450 2B1-like; Belongs to the cytochrome P450 family. (491 aa)
LOC101844221Cytochrome P450 2B1-like; Belongs to the cytochrome P450 family. (491 aa)
Degs1Sphingolipid delta(4)-desaturase DES1. (307 aa)
PtgisProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (493 aa)
Scd2acyl-CoA desaturase 2-like. (331 aa)
ENSMAUP00000017505annotation not available (207 aa)
Nos2Nitric oxide synthase; Produces nitric oxide (NO). (1156 aa)
Tti2TELO2-interacting protein 2. (516 aa)
Akr1c18Aldo-keto reductase family 1 member C18 isoform X1. (323 aa)
Phf2Lysine-specific demethylase PHF2. (1077 aa)
CmahCytidine monophosphate-N-acetylneuraminic acid hydroxylase. (577 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (80 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1202 aa)
Tmem189Transmembrane protein 189. (251 aa)
Jmjd4jmjC domain-containing protein 4. (426 aa)
ENSMAUP00000018841annotation not available (120 aa)
CrtapCartilage-associated protein. (398 aa)
ENSMAUP00000019005annotation not available (354 aa)
Cyp2s1Cytochrome P450 2S1 isoform X1; Belongs to the cytochrome P450 family. (500 aa)
Kdm1bLysine-specific histone demethylase 1B. (806 aa)
Akr1c143-alpha-hydroxysteroid dehydrogenase-like isoform X1. (323 aa)
Phf8Histone lysine demethylase PHF8 isoform X1. (1023 aa)
P3h4Synaptonemal complex protein SC65. (447 aa)
LOC1018433113-hydroxyhexobarbital dehydrogenase 1/3-alpha, 17-beta-hydroxysteroid dehydrogenase. (323 aa)
P4ha3Prolyl 4-hydroxylase subunit alpha-3. (520 aa)
Fads6Fatty acid desaturase 6. (342 aa)
P4hbProtein disulfide-isomerase. (509 aa)
Kdm2aLysine-specific demethylase 2A. (496 aa)
Moxd1DBH-like monooxygenase protein 1. (613 aa)
PahPhenylalanine-4-hydroxylase. (453 aa)
Phyhd1LOW QUALITY PROTEIN: phytanoyl-CoA dioxygenase domain-containing protein 1. (207 aa)
ThTyrosine 3-monooxygenase. (498 aa)
Tet3Methylcytosine dioxygenase TET3 isoform X1. (1802 aa)
Scd1acyl-CoA desaturase 1-like. (212 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
LOC101835628Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid ox [...] (350 aa)
LOC106021304Cytochrome P450 4A10-like. (368 aa)
Kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (870 aa)
Fmo6Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
HrLysine-specific demethylase hairless. (1192 aa)
Jmjd8jmjC domain-containing protein 8. (310 aa)
ENSMAUP00000021460annotation not available (280 aa)
P3h3Prolyl 3-hydroxylase 3 isoform X1. (737 aa)
Alkbh4Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 isoform X2. (306 aa)
P3h2Prolyl 3-hydroxylase 2. (704 aa)
Cyp8b17-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
SqleSqualene monooxygenase. (573 aa)
LOC101843587Aldo-keto reductase family 1 member C21-like isoform X1. (319 aa)
LOC101835264Sphingolipid delta(4)-desaturase DES1-like. (182 aa)
Fmo3Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
LOC101830700Cytochrome P450 2J3 isoform X1; Belongs to the cytochrome P450 family. (502 aa)
Saal1Protein SAAL1. (474 aa)
Plod2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X1. (761 aa)
LOC101841267prostaglandin-E(2) 9-reductase-like isoform X2. (311 aa)
Cyp26a1Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa)
Tph1Tryptophan 5-hydroxylase 1. (443 aa)
Cyp4f40Cytochrome P450 4F4-like; Belongs to the cytochrome P450 family. (532 aa)
LOC101839651Aldo-keto reductase family 1 member C21-like. (310 aa)
LOC101843716Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (493 aa)
Cyp26b1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
Ch25hCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (284 aa)
LOC101844487Cytochrome P450, family 2 subfamily B polypeptide 29; Belongs to the cytochrome P450 family. (491 aa)
Kdm4cLysine-specific demethylase 4C. (371 aa)
LOC101831088Cytochrome P450 2C26; Catalyzes the hydroxylation of tolbutamide and the N- demethylation of aminopyrine and benzphetamine. (490 aa)
Degs2Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2. (311 aa)
LOC101842758Cytochrome P450 4V2; Belongs to the cytochrome P450 family. (522 aa)
Riox1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (567 aa)
Fmo1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
Scd3acyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (326 aa)
Hif1anHypoxia-inducible factor 1-alpha inhibitor. (349 aa)
Cyp2r1Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
Egln1Egl nine homolog 1. (126 aa)
Cyp2t4LOW QUALITY PROTEIN: cytochrome P450 2F3-like. (478 aa)
LOC101842245Aldo-keto reductase family 1 member C13-like isoform X1. (311 aa)
Cyp7b125-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (509 aa)
LOC101826941Cytochrome P450 2A3-like; Belongs to the cytochrome P450 family. (494 aa)
LOC101823450Cytochrome P450 2C25-like. (383 aa)
Fmo5Flavin containing dimethylaniline monoxygenase 5. (368 aa)
LOC101830378Cytochrome P450 2C26-like isoform X2; Belongs to the cytochrome P450 family. (490 aa)
Plod1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (727 aa)
LOC101830438Cytochrome P450 2J3-like isoform X1; Belongs to the cytochrome P450 family. (502 aa)
Cyp2j6Cytochrome P450 2J6-like; Belongs to the cytochrome P450 family. (421 aa)
ENSMAUP00000024381annotation not available (327 aa)
ENSMAUP00000024468annotation not available (458 aa)
Kdm2bLysine-specific demethylase 2B. (1299 aa)
LOC101829291Cytochrome P450 4F5-like; Belongs to the cytochrome P450 family. (524 aa)
Ogfod22-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 isoform X1. (349 aa)
Cyp2w1Cytochrome P450 2W1; Belongs to the cytochrome P450 family. (493 aa)
AsphAspartyl/asparaginyl beta-hydroxylase isoform X8. (211 aa)
Cyp4f39Cytochrome P450 4F22; Belongs to the cytochrome P450 family. (532 aa)
Cyp2g1Cytochrome P450 2G1 isoform X1; Belongs to the cytochrome P450 family. (494 aa)
LOC101831527Cytochrome P450 2C19-like; Belongs to the cytochrome P450 family. (490 aa)
Phyhphytanoyl-CoA dioxygenase, peroxisomal. (338 aa)
ENSMAUP00000024979annotation not available (426 aa)
PigsGPI transamidase component PIG-S. (555 aa)
Cyp26c1Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (516 aa)
P3h1Prolyl 3-hydroxylase 1. (739 aa)
LOC101841752Cytochrome P450 2C27-like. (401 aa)
LOC101825889Cytochrome P450 2A8; Highly active in 7-ethoxycoumarin O-deethylation, and benzphetamine N-demethylation; moderately active in testosterone 7- alpha-hydroxylation, ethylmorphine N-demethylation, p-nitroanisole O- demethylation; and only slightly active in benzopyrene 3-hydroxylation, 7-ethoxyresorufin O-deethylation, testosterone 2-alpha-hydroxylation and testosterone 17-oxidation. Competent in the metabolic activation of aflatoxin B1; Belongs to the cytochrome P450 family. (494 aa)
TyrTyrosinase. (530 aa)
Ccdc160Coiled-coil domain-containing protein 160 isoform X2. (323 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
MicalclMICAL C-terminal-like protein. (690 aa)
KmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (479 aa)
FtoAlpha-ketoglutarate-dependent dioxygenase FTO. (502 aa)
LOC101833813Cytochrome P450 2B1-like. (456 aa)
Coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (216 aa)
AgmoAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (449 aa)
P4ha2Prolyl 4-hydroxylase subunit alpha-2. (529 aa)
Tet1Methylcytosine dioxygenase TET1. (1957 aa)
Mical1F-actin-methionine sulfoxide oxidase MICAL1 isoform X2. (1049 aa)
LOC101844281Cytochrome P450 20A1. (216 aa)
Kdm5bLysine-specific demethylase 5B isoform X2. (1543 aa)
Ptgs1Prostaglandin G/H synthase 1. (607 aa)
LOC101832144Cytochrome P450 2C28; Catalyzes the N-demethylation of aminopyrine and benzphetamine, but does not catalyze the hydroxylation of tolbutamide, testosterone, and progesterone; Belongs to the cytochrome P450 family. (490 aa)
LOC101838830LOW QUALITY PROTEIN: cytochrome P450 2D20-like; Belongs to the cytochrome P450 family. (476 aa)
LOC101823194Cytochrome P450 4A12; Belongs to the cytochrome P450 family. (508 aa)
LOC101842021Cytochrome P450 2C26-like; Belongs to the cytochrome P450 family. (217 aa)
Cyp2f2Cytochrome P450 2F2; Belongs to the cytochrome P450 family. (491 aa)
Gm12248Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family. (343 aa)
Cyp21a1Steroid 21-hydroxylase isoform X2; Belongs to the cytochrome P450 family. (496 aa)
Tstd2Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1. (493 aa)
Kdm4bLysine-specific demethylase 4B. (1040 aa)
Alkbh8LOW QUALITY PROTEIN: alkylated DNA repair protein alkB homolog 8. (530 aa)
LOC101827747Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
LOC101823339Cytochrome P450 11B1, mitochondrial; A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) [...] (319 aa)
Kdm3aLysine-specific demethylase 3A. (820 aa)
Bbox1Gamma-butyrobetaine dioxygenase. (387 aa)
Cyp24a11,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
LOC101836914Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (473 aa)
PamPeptidyl-glycine alpha-amidating monooxygenase isoform X1. (980 aa)
Cyp46a1Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa)
Cyp2ab1Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (280 aa)
LOC101826047Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (200 aa)
Cyp2c70Cytochrome P450 2C70-like; Belongs to the cytochrome P450 family. (489 aa)
Alkbh1Nucleic acid dioxygenase ALKBH1. (350 aa)
Cyp1a1Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (507 aa)
Fads2bFatty acid desaturase 2-like protein FADS2P1 isoform X1. (481 aa)
Cyp1b1Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (541 aa)
Fads2Fatty acid desaturase 2. (444 aa)
Mettl26Methyltransferase like 26. (107 aa)
Kdm5aLysine-specific demethylase 5A. (617 aa)
Alkbh5RNA demethylase ALKBH5. (395 aa)
DbhDopamine beta-hydroxylase. (620 aa)
Kdm6bLysine-specific demethylase 6B isoform X4. (1652 aa)
Fads1Fatty acid desaturase 1 isoform X1. (447 aa)
Gm4847Dimethylaniline monooxygenase [N-oxide-forming]. (538 aa)
Fmo2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
Cyp27b125-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa)
DohhDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (302 aa)
Ccndbp1cyclin-D1-binding protein 1. (305 aa)
Kdm6aLysine-specific demethylase 6A. (1383 aa)
Mical2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (851 aa)
LOC101841191Cytochrome P450 2J3-like. (443 aa)
Cyp4f14leukotriene-B4 omega-hydroxylase 3 isoform X2; Belongs to the cytochrome P450 family. (524 aa)
ENSMAUP00000007047annotation not available (75 aa)
Cyp1a2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (513 aa)
Tbxas1thromboxane-A synthase. (428 aa)
Cyp4f13Cytochrome P450 4F6 isoform X1; Belongs to the cytochrome P450 family. (524 aa)
LOC101830103Cytochrome P450 4F5 isoform X1; Belongs to the cytochrome P450 family. (524 aa)
Pcbd1Pterin-4-alpha-carbinolamine dehydratase. (104 aa)
Alkbh2DNA oxidative demethylase ALKBH2. (239 aa)
Tet2Methylcytosine dioxygenase TET2 isoform X1. (1926 aa)
Tyw5tRNA wybutosine-synthesizing protein 5 isoform X1. (315 aa)
Fmo4Dimethylaniline monooxygenase [N-oxide-forming]. (557 aa)
Cyp3a13Cytochrome P450 3A9. (503 aa)
Hmox2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
Kdm7aLysine-specific demethylase 7A. (893 aa)
Fmo9Flavin-containing monooxygenase. (539 aa)
Cyp4a30bCytochrome P450 4A14-like; Belongs to the cytochrome P450 family. (477 aa)
Kdm5cLysine-specific demethylase 5C. (1131 aa)
Mical3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (56 aa)
Kdm4dLysine-specific demethylase 4D. (521 aa)
PorNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (672 aa)
P4htmTransmembrane prolyl 4-hydroxylase. (502 aa)
P4ha1Prolyl 4-hydroxylase subunit alpha-1. (489 aa)
Coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (471 aa)
Jmjd6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1. (403 aa)
Akr1d13-oxo-5-beta-steroid 4-dehydrogenase. (325 aa)
Kdm8Lysine-specific demethylase 8 isoform X1. (417 aa)
LOC101831958Lithocholate 6-beta-hydroxylase; Catalyzes the 6 beta-hydroxylation of lithocholic acid and steroid hormones; Belongs to the cytochrome P450 family. (503 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
TmlheTrimethyllysine dioxygenase, mitochondrial isoform X2. (421 aa)
Cyp4b1Cytochrome P450 4B1; Belongs to the cytochrome P450 family. (509 aa)
ENSMAUP00000011252annotation not available (94 aa)
Cyp4x1Cytochrome P450 4X1; Belongs to the cytochrome P450 family. (505 aa)
Tph2Tryptophan 5-hydroxylase 2. (490 aa)
Kdm4aLysine-specific demethylase 4A. (1063 aa)
Msmo1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa)
Ogfod32-oxoglutarate and iron-dependent oxygenase domain-containing protein 3. (316 aa)
Egln3Egl nine homolog 3. (259 aa)
Cyp27a1Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (534 aa)
Fads3Fatty acid desaturase 3. (449 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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