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LOC101826941 LOC101826941 Cyp7a1 Cyp7a1 LOC101831958 LOC101831958 Coq6 Coq6 Hmox2 Hmox2 Cyp3a13 Cyp3a13 Cyp1a2 Cyp1a2 Cyp4f14 Cyp4f14 LOC101841191 LOC101841191 LOC101832144 LOC101832144 Cyp2c70 Cyp2c70 LOC101830700 LOC101830700 Cyp4f40 Cyp4f40 LOC101843716 LOC101843716 LOC101844487 LOC101844487 LOC101831088 LOC101831088 LOC101823450 LOC101823450 Cyp2w1 Cyp2w1 Cyp2g1 Cyp2g1 LOC101831527 LOC101831527 Cyp4b1 Cyp4b1 LOC101838830 LOC101838830 Cyp1a1 Cyp1a1 Cyp2f2 Cyp2f2 LOC101825889 LOC101825889 Hmox1 Hmox1 LOC101833813 LOC101833813 LOC101842021 LOC101842021 LOC101830378 LOC101830378 LOC101830438 LOC101830438 Cyp2j6 Cyp2j6 LOC101841752 LOC101841752 ENSMAUP00000024979 ENSMAUP00000024979 Cyp1b1 Cyp1b1 LOC101836914 LOC101836914 Cyp2ab1 Cyp2ab1 Cyp19a1 Cyp19a1 Cyp2u1 Cyp2u1 LOC101826326 LOC101826326 LOC101844759 LOC101844759 LOC101844221 LOC101844221 Tti2 Tti2 ENSMAUP00000018841 ENSMAUP00000018841 ENSMAUP00000019005 ENSMAUP00000019005 Cyp2s1 Cyp2s1 Cyp2r1 Cyp2r1 Cyp2t4 Cyp2t4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101826941Cytochrome P450 2A3-like; Belongs to the cytochrome P450 family. (494 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
LOC101831958Lithocholate 6-beta-hydroxylase; Catalyzes the 6 beta-hydroxylation of lithocholic acid and steroid hormones; Belongs to the cytochrome P450 family. (503 aa)
Coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (471 aa)
Hmox2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
Cyp3a13Cytochrome P450 3A9. (503 aa)
Cyp1a2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (513 aa)
Cyp4f14leukotriene-B4 omega-hydroxylase 3 isoform X2; Belongs to the cytochrome P450 family. (524 aa)
LOC101841191Cytochrome P450 2J3-like. (443 aa)
LOC101832144Cytochrome P450 2C28; Catalyzes the N-demethylation of aminopyrine and benzphetamine, but does not catalyze the hydroxylation of tolbutamide, testosterone, and progesterone; Belongs to the cytochrome P450 family. (490 aa)
Cyp2c70Cytochrome P450 2C70-like; Belongs to the cytochrome P450 family. (489 aa)
LOC101830700Cytochrome P450 2J3 isoform X1; Belongs to the cytochrome P450 family. (502 aa)
Cyp4f40Cytochrome P450 4F4-like; Belongs to the cytochrome P450 family. (532 aa)
LOC101843716Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (493 aa)
LOC101844487Cytochrome P450, family 2 subfamily B polypeptide 29; Belongs to the cytochrome P450 family. (491 aa)
LOC101831088Cytochrome P450 2C26; Catalyzes the hydroxylation of tolbutamide and the N- demethylation of aminopyrine and benzphetamine. (490 aa)
LOC101823450Cytochrome P450 2C25-like. (383 aa)
Cyp2w1Cytochrome P450 2W1; Belongs to the cytochrome P450 family. (493 aa)
Cyp2g1Cytochrome P450 2G1 isoform X1; Belongs to the cytochrome P450 family. (494 aa)
LOC101831527Cytochrome P450 2C19-like; Belongs to the cytochrome P450 family. (490 aa)
Cyp4b1Cytochrome P450 4B1; Belongs to the cytochrome P450 family. (509 aa)
LOC101838830LOW QUALITY PROTEIN: cytochrome P450 2D20-like; Belongs to the cytochrome P450 family. (476 aa)
Cyp1a1Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (507 aa)
Cyp2f2Cytochrome P450 2F2; Belongs to the cytochrome P450 family. (491 aa)
LOC101825889Cytochrome P450 2A8; Highly active in 7-ethoxycoumarin O-deethylation, and benzphetamine N-demethylation; moderately active in testosterone 7- alpha-hydroxylation, ethylmorphine N-demethylation, p-nitroanisole O- demethylation; and only slightly active in benzopyrene 3-hydroxylation, 7-ethoxyresorufin O-deethylation, testosterone 2-alpha-hydroxylation and testosterone 17-oxidation. Competent in the metabolic activation of aflatoxin B1; Belongs to the cytochrome P450 family. (494 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
LOC101833813Cytochrome P450 2B1-like. (456 aa)
LOC101842021Cytochrome P450 2C26-like; Belongs to the cytochrome P450 family. (217 aa)
LOC101830378Cytochrome P450 2C26-like isoform X2; Belongs to the cytochrome P450 family. (490 aa)
LOC101830438Cytochrome P450 2J3-like isoform X1; Belongs to the cytochrome P450 family. (502 aa)
Cyp2j6Cytochrome P450 2J6-like; Belongs to the cytochrome P450 family. (421 aa)
LOC101841752Cytochrome P450 2C27-like. (401 aa)
ENSMAUP00000024979annotation not available (426 aa)
Cyp1b1Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (541 aa)
LOC101836914Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (473 aa)
Cyp2ab1Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (280 aa)
Cyp19a1Aromatase; Belongs to the cytochrome P450 family. (503 aa)
Cyp2u1Cytochrome P450 2U1; Belongs to the cytochrome P450 family. (532 aa)
LOC101826326Cytochrome P450 2A9; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (493 aa)
LOC101844759Cytochrome P450 2B1-like; Belongs to the cytochrome P450 family. (491 aa)
LOC101844221Cytochrome P450 2B1-like; Belongs to the cytochrome P450 family. (491 aa)
Tti2TELO2-interacting protein 2. (516 aa)
ENSMAUP00000018841annotation not available (120 aa)
ENSMAUP00000019005annotation not available (354 aa)
Cyp2s1Cytochrome P450 2S1 isoform X1; Belongs to the cytochrome P450 family. (500 aa)
Cyp2r1Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
Cyp2t4LOW QUALITY PROTEIN: cytochrome P450 2F3-like. (478 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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