STRINGSTRING
Med7 Med7 LOC101836188 LOC101836188 Tet1 Tet1 Gata2 Gata2 Med6 Med6 ENSMAUP00000004961 ENSMAUP00000004961 Med24 Med24 Vps72 Vps72 Tcl1a Tcl1a Setd6 Setd6 Arid1a Arid1a Prdm14 Prdm14 Elf5 Elf5 Piwil2 Piwil2 Hes1 Hes1 Rif1 Rif1 Pou5f1 Pou5f1 Fgfr3 Fgfr3 Dll1 Dll1 Fancc Fancc Faxc Faxc Nodal Nodal Fgf10 Fgf10 Dis3l2 Dis3l2 Med14 Med14 Med28 Med28 Nog Nog Klf4 Klf4 Sox4 Sox4 ENSMAUP00000005832 ENSMAUP00000005832 Kdm4c Kdm4c Med17 Med17 Klf10 Klf10 Smarca4 Smarca4 Med12 Med12 Cdx2 Cdx2 Leo1 Leo1 Fut10 Fut10 Cdc73 Cdc73 Tcf15 Tcf15 Zhx2 Zhx2 Eif4enif1 Eif4enif1 Jmjd1c Jmjd1c Hesx1 Hesx1 Foxo1 Foxo1 Esrrb Esrrb Srrt Srrt Stag2 Stag2 Fancd2 Fancd2 Dppa2 Dppa2 ENSMAUP00000009932 ENSMAUP00000009932 Aspm Aspm Bcl9l Bcl9l Crebbp Crebbp Fzd7 Fzd7 Tut4 Tut4 Med10 Med10 Eomes Eomes Six2 Six2 Smc5 Smc5 Dicer1 Dicer1 Pelo Pelo Prox1 Prox1 Zic3 Zic3 Ddx6 Ddx6 Spi1 Spi1 Stat3 Stat3 Hmga2 Hmga2 Smc1a Smc1a Wnt7a Wnt7a Mmp24 Mmp24 Ctr9 Ctr9 Bmpr1a Bmpr1a Mtf2 Mtf2 Braf Braf Sall4 Sall4 Tcf7l1 Tcf7l1 Prdm16 Prdm16 LOC101836245 LOC101836245 Jag1 Jag1 Trim8 Trim8 Hook3 Hook3 Smc3 Smc3 ENSMAUP00000015340 ENSMAUP00000015340 Sox2 Sox2 Wnt9b Wnt9b Lsm1 Lsm1 Vangl2 Vangl2 Nipbl Nipbl Tbx3 Tbx3 LOC101839191 LOC101839191 Med30 Med30 Kat6a Kat6a Tcf7l2 Tcf7l2 Mettl3 Mettl3 Mettl14 Mettl14 Tpt1 Tpt1 Ski Ski Foxo3 Foxo3 Kit Kit ENSMAUP00000013777 ENSMAUP00000013777 Nr2e1 Nr2e1 Apc Apc Lif Lif Lrp5 Lrp5 Fgfr1 Fgfr1 Paf1 Paf1 Ldb1 Ldb1 Fgf4 Fgf4 Prrx1 Prrx1 Phf19 Phf19 Lin28a Lin28a Lig4 Lig4 Ascl2 Ascl2 Sall1 Sall1 Pcm1 Pcm1 Sct Sct Ss18 Ss18 ENSMAUP00000021866 ENSMAUP00000021866 Tfap2c Tfap2c Rtf1 Rtf1 Hes5 Hes5 Med15 Med15 Ldb2 Ldb2 Med21 Med21 ENSMAUP00000022526 ENSMAUP00000022526 Sfrp1 Sfrp1 Gnl3 Gnl3 Nkap Nkap ENSMAUP00000023105 ENSMAUP00000023105 Padi4 Padi4 Sox9 Sox9 Rbpj Rbpj Bcl9 Bcl9 Cdh2 Cdh2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Med7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (233 aa)
LOC101836188Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
Tet1Methylcytosine dioxygenase TET1. (1957 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Med6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (246 aa)
ENSMAUP00000004961annotation not available (107 aa)
Med24Mediator of RNA polymerase II transcription subunit 24 isoform X1. (1006 aa)
Vps72LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 72 homolog. (317 aa)
Tcl1aT-cell leukemia/lymphoma protein 1A. (172 aa)
Setd6N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (472 aa)
Arid1aAT-rich interactive domain-containing protein 1A. (1017 aa)
Prdm14PR domain zinc finger protein 14. (557 aa)
Elf5ETS-related transcription factor Elf-5. (253 aa)
Piwil2Piwi-like protein 2; Belongs to the argonaute family. (804 aa)
Hes1Transcription factor HES-1. (281 aa)
Rif1Telomere-associated protein RIF1. (2298 aa)
Pou5f1POU domain protein. (358 aa)
Fgfr3Fibroblast growth factor receptor. (802 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (733 aa)
FanccFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (584 aa)
FaxcFailed axon connections homolog. (408 aa)
NodalNodal homolog. (354 aa)
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (884 aa)
Med14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1451 aa)
Med28Mediator of RNA polymerase II transcription subunit 28. (247 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
Klf4Krueppel-like factor 4. (485 aa)
Sox4Transcription factor SOX. (439 aa)
ENSMAUP00000005832annotation not available (138 aa)
Kdm4cLysine-specific demethylase 4C. (371 aa)
Med17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (634 aa)
Klf10Krueppel-like factor 10. (477 aa)
Smarca4Transcription activator BRG1 isoform X3. (1646 aa)
Med12Mediator of RNA polymerase II transcription subunit 12 isoform X1. (2186 aa)
Cdx2Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA (By similarity). (313 aa)
Leo1RNA polymerase-associated protein LEO1. (622 aa)
Fut10Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (481 aa)
Cdc73Parafibromin. (531 aa)
Tcf15Transcription factor 15; May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm. (195 aa)
Zhx2Zinc fingers and homeoboxes protein 2. (838 aa)
Eif4enif1Eukaryotic translation initiation factor 4E transporter. (937 aa)
Jmjd1cProbable JmjC domain-containing histone demethylation protein 2C. (740 aa)
Hesx1Homeobox expressed in ES cells 1. (185 aa)
Foxo1Forkhead box protein O1. (633 aa)
EsrrbEstrogen-related receptor gamma. (367 aa)
SrrtSerrate RNA effector molecule homolog isoform X1. (875 aa)
Stag2Cohesin subunit SA-2 isoform X1. (1268 aa)
Fancd2Fanconi anemia group D2 protein. (1385 aa)
Dppa2Developmental pluripotency-associated protein 2. (256 aa)
ENSMAUP00000009932annotation not available (203 aa)
AspmAbnormal spindle-like microcephaly-associated protein. (3033 aa)
Bcl9lB-cell CLL/lymphoma 9-like protein isoform X1. (1498 aa)
CrebbpCREB-binding protein. (2433 aa)
Fzd7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (572 aa)
Tut4Terminal uridylyltransferase 4. (1005 aa)
Med10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (135 aa)
EomesEomesodermin homolog isoform X1. (703 aa)
Six2Homeobox protein SIX2. (296 aa)
Smc5Structural maintenance of chromosomes protein 5 isoform X1. (1102 aa)
Dicer1Endoribonuclease Dicer isoform X1; Belongs to the helicase family. Dicer subfamily. (1917 aa)
PeloProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
Prox1Prospero homeobox protein 1 isoform X2. (734 aa)
Zic3Zinc finger protein ZIC 3. (466 aa)
Ddx6Probable ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
Spi1Transcription factor PU.1 isoform X1. (273 aa)
Stat3Signal transducer and activator of transcription. (758 aa)
Hmga2High mobility group protein HMGI-C isoform X1. (108 aa)
Smc1aStructural maintenance of chromosomes protein. (1233 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (318 aa)
Mmp24Matrix metalloproteinase-24. (593 aa)
Ctr9RNA polymerase-associated protein CTR9 homolog. (1171 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Mtf2Metal-response element-binding transcription factor 2 isoform X1. (593 aa)
BrafSerine/threonine-protein kinase B-raf. (710 aa)
Sall4Sal-like protein 4 isoform X1. (1061 aa)
Tcf7l1Transcription factor 7-like 1. (558 aa)
Prdm16PR domain zinc finger protein 16 isoform X3. (1247 aa)
LOC101836245Mediator of RNA polymerase II transcription subunit 27 isoform X1. (100 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
Trim8Probable E3 ubiquitin-protein ligase TRIM8. (551 aa)
Hook3Protein Hook homolog 3 isoform X2. (718 aa)
Smc3Structural maintenance of chromosomes protein. (1217 aa)
ENSMAUP00000015340annotation not available (121 aa)
Sox2Transcription factor SOX-2. (319 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
Lsm1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (111 aa)
Vangl2Vang-like protein. (320 aa)
NipblNipped-B protein. (2799 aa)
Tbx3T-box transcription factor TBX3. (130 aa)
LOC101839191RE1-silencing transcription factor-like. (301 aa)
Med30Mediator of RNA polymerase II transcription subunit 30. (178 aa)
Kat6aHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (840 aa)
Tcf7l2Transcription factor 7-like 2 isoform X17. (598 aa)
Mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
Mettl14N6-adenosine-methyltransferase subunit METTL14; Belongs to the MT-A70-like family. (456 aa)
Tpt1Translationally-controlled tumor protein; Belongs to the TCTP family. (172 aa)
SkiSki oncogene isoform X1. (727 aa)
Foxo3Forkhead box protein O3. (672 aa)
KitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
ENSMAUP00000013777annotation not available (113 aa)
Nr2e1Nuclear receptor subfamily 2 group E member 1. (387 aa)
ApcAdenomatous polyposis coli protein isoform X4. (492 aa)
LifLeukemia inhibitory factor isoform X1. (202 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1614 aa)
Fgfr1Fibroblast growth factor receptor. (819 aa)
Paf1RNA polymerase II-associated factor 1 homolog. (535 aa)
Ldb1LIM domain-binding protein 1 isoform X1. (398 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (52 aa)
Prrx1Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
Phf19PHD finger protein 19. (580 aa)
Lin28aProtein lin-28 homolog A. (209 aa)
Lig4DNA ligase. (848 aa)
Ascl2Achaete-scute homolog 2. (193 aa)
Sall1Sal-like protein 1. (1318 aa)
Pcm1Pericentriolar material 1 protein isoform X7. (2068 aa)
SctSecretin isoform X1. (134 aa)
Ss18Protein SSXT isoform X1. (418 aa)
ENSMAUP00000021866annotation not available (131 aa)
Tfap2cLOW QUALITY PROTEIN: transcription factor AP-2 gamma. (440 aa)
Rtf1RNA polymerase-associated protein RTF1 homolog. (712 aa)
Hes5Transcription factor HES-5. (166 aa)
Med15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (783 aa)
Ldb2LIM domain-binding protein 2 isoform X1. (373 aa)
Med21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (144 aa)
ENSMAUP00000022526annotation not available (162 aa)
Sfrp1Secreted frizzled-related protein 1. (314 aa)
Gnl3Guanine nucleotide-binding protein-like 3. (531 aa)
NkapNF-kappa-B-activating protein. (335 aa)
ENSMAUP00000023105annotation not available (135 aa)
Padi4Protein-arginine deiminase type-4. (527 aa)
Sox9Transcription factor SOX-9. (507 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Bcl9B-cell CLL/lymphoma 9 protein isoform X1. (1425 aa)
Cdh2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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