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Tgfb3 Tgfb3 LOC101840621 LOC101840621 LOC101835406 LOC101835406 Scn2a Scn2a Cacna1s Cacna1s Ppp3cb Ppp3cb Cacna2d1 Cacna2d1 Cacnb2 Cacnb2 ENSMAUP00000003329 ENSMAUP00000003329 Cacng1 Cacng1 ENSMAUP00000002072 ENSMAUP00000002072 Casq1 Casq1 ENSMAUP00000001689 ENSMAUP00000001689 Slc9a1 Slc9a1 Fer1l5 Fer1l5 LOC101837672 LOC101837672 Scn1b Scn1b Prkce Prkce Abcc9 Abcc9 Cacng8 Cacng8 Slc30a1 Slc30a1 Kcnj2 Kcnj2 ENSMAUP00000022827 ENSMAUP00000022827 Dysf Dysf ENSMAUP00000021988 ENSMAUP00000021988 Asb15 Asb15 Adra1a Adra1a Cav3 Cav3 Rtn2 Rtn2 Kcnj12 Kcnj12 Got2 Got2 Kcnj3 Kcnj3 Cacna1c Cacna1c Atp1b1 Atp1b1 Aqp4 Aqp4 Atp1a1 Atp1a1 Slc2a4 Slc2a4 Nos1 Nos1 Ednra Ednra Ryr1 Ryr1 Cacnb1 Cacnb1 Cacng7 Cacng7 Bin1 Bin1 Vdr Vdr Scn5a Scn5a Ank3 Ank3 Cdh2 Cdh2 Kcnd2 Kcnd2 Akap6 Akap6 Slc8a1 Slc8a1 Kcnn2 Kcnn2 Camk2d Camk2d Fxyd1 Fxyd1 Akap7 Akap7 Cacnb3 Cacnb3 Kcnj5 Kcnj5 ENSMAUP00000010641 ENSMAUP00000010641 Stac Stac Igf1r Igf1r Sri Sri Cltc Cltc Cacng4 Cacng4 Atp1a2 Atp1a2 Cacng6 Cacng6 Asb3 Asb3 ENSMAUP00000006623 ENSMAUP00000006623 Prkar2a Prkar2a Ankrd39 Ankrd39 Atp2b4 Atp2b4 Ezr Ezr Stbd1 Stbd1 Kcnj11 Kcnj11 Msn Msn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LOC101840621G protein-activated inward rectifier potassium channel 1. (234 aa)
LOC101835406Calpain-3-like. (191 aa)
Scn2aSodium voltage-gated channel alpha subunit 2. (1686 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
Ppp3cbSerine/threonine-protein phosphatase. (483 aa)
Cacna2d1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1017 aa)
Cacnb2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (655 aa)
ENSMAUP00000003329annotation not available (502 aa)
Cacng1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
ENSMAUP00000002072annotation not available (92 aa)
Casq1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (401 aa)
ENSMAUP00000001689annotation not available (1186 aa)
Slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (412 aa)
Fer1l5Fer-1-like protein 5. (1965 aa)
LOC101837672Reticulon-2. (195 aa)
Scn1bSodium channel subunit beta-1. (218 aa)
PrkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (623 aa)
Abcc9ATP-binding cassette sub-family C member 9 isoform X2. (1550 aa)
Cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (412 aa)
Slc30a1LOW QUALITY PROTEIN: zinc transporter 1. (478 aa)
Kcnj2Inward rectifier potassium channel 2. (427 aa)
ENSMAUP00000022827annotation not available (111 aa)
DysfDysferlin isoform X14. (2128 aa)
ENSMAUP00000021988annotation not available (775 aa)
Asb15Ankyrin repeat and SOCS box protein 15. (588 aa)
Adra1aalpha-1A adrenergic receptor isoform X1. (465 aa)
Cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
Rtn2Reticulon. (269 aa)
Kcnj12ATP-sensitive inward rectifier potassium channel 12 isoform X2. (530 aa)
Got2Aspartate aminotransferase. (430 aa)
Kcnj3LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 1. (194 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
Atp1b1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
Aqp4Aquaporin-4 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
Atp1a1Sodium/potassium-transporting ATPase subunit alpha. (1019 aa)
Slc2a4Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (510 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (80 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
Ryr1LOW QUALITY PROTEIN: ryanodine receptor 1. (4094 aa)
Cacnb1Voltage-dependent L-type calcium channel subunit beta-1 isoform X1. (677 aa)
Cacng7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
Bin1Myc box-dependent-interacting protein 1. (587 aa)
VdrVitamin D3 receptor. (423 aa)
Scn5aSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2021 aa)
Ank3Ankyrin-3 isoform X20. (2626 aa)
Cdh2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
Kcnd2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
Akap6A kinase (PRKA) anchor protein 6. (1639 aa)
Slc8a1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
Kcnn2Small conductance calcium-activated potassium channel protein 2 isoform X1. (839 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
Fxyd1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
Akap7A-kinase anchor protein 7 isoform X5. (335 aa)
Cacnb3Voltage-dependent L-type calcium channel subunit beta-3 isoform X2. (484 aa)
Kcnj5G protein-activated inward rectifier potassium channel 4. (343 aa)
ENSMAUP00000010641annotation not available (100 aa)
StacSH3 and cysteine-rich domain-containing protein. (324 aa)
Igf1rTyrosine-protein kinase receptor. (1154 aa)
SriSorcin isoform X2. (198 aa)
CltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
Cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha. (918 aa)
Cacng6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
Asb3Ankyrin repeat and SOCS box protein 3. (398 aa)
ENSMAUP00000006623annotation not available (500 aa)
Prkar2acAMP-dependent protein kinase type II-alpha regulatory subunit. (402 aa)
Ankrd39Ankyrin repeat domain-containing protein 39 isoform X2. (183 aa)
Atp2b4ATPase plasma membrane Ca2+ transporting 4. (1038 aa)
EzrEzrin. (576 aa)
Stbd1Starch-binding domain-containing protein 1. (76 aa)
Kcnj11ATP-sensitive inward rectifier potassium channel 11 isoform X1. (390 aa)
MsnMoesin. (579 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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