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Acd | Adrenocortical dysplasia protein homolog isoform X2. (409 aa) | ||||
Gnl3l | Guanine nucleotide-binding protein-like 3-like protein. (577 aa) | ||||
Dcp2 | m7GpppN-mRNA hydrolase isoform X1. (423 aa) | ||||
Nat10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (813 aa) | ||||
Ten1 | CST complex subunit TEN1. (158 aa) | ||||
ENSMAUP00000008641 | annotation not available (186 aa) | ||||
Src | Tyrosine-protein kinase. (536 aa) | ||||
Pif1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (650 aa) | ||||
Hnrnpu | Heterogeneous nuclear ribonucleoprotein U. (813 aa) | ||||
Pinx1 | PIN2/TERF1-interacting telomerase inhibitor 1 isoform X2. (330 aa) | ||||
ENSMAUP00000003314 | annotation not available (266 aa) | ||||
Terf1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (405 aa) | ||||
Terf2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa) | ||||
ENSMAUP00000023853 | annotation not available (267 aa) | ||||
Ctc1 | CST complex subunit CTC1 isoform X3. (1213 aa) | ||||
Pot1 | Protection of telomeres protein 1. (639 aa) | ||||
Exosc10 | Exosome component 10. (618 aa) | ||||
Hnrnpa1 | Heterogeneous nuclear ribonucleoprotein A1 isoform X2. (320 aa) | ||||
Tent4b | Non-canonical poly(A) RNA polymerase PAPD5 isoform X1. (685 aa) | ||||
Stn1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (399 aa) |