STRINGSTRING
Acd Acd Gnl3l Gnl3l Dcp2 Dcp2 Nat10 Nat10 Ten1 Ten1 ENSMAUP00000008641 ENSMAUP00000008641 Src Src Pif1 Pif1 Hnrnpu Hnrnpu Pinx1 Pinx1 ENSMAUP00000003314 ENSMAUP00000003314 Terf1 Terf1 Terf2 Terf2 ENSMAUP00000023853 ENSMAUP00000023853 Ctc1 Ctc1 Pot1 Pot1 Exosc10 Exosc10 Hnrnpa1 Hnrnpa1 Tent4b Tent4b Stn1 Stn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AcdAdrenocortical dysplasia protein homolog isoform X2. (409 aa)
Gnl3lGuanine nucleotide-binding protein-like 3-like protein. (577 aa)
Dcp2m7GpppN-mRNA hydrolase isoform X1. (423 aa)
Nat10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (813 aa)
Ten1CST complex subunit TEN1. (158 aa)
ENSMAUP00000008641annotation not available (186 aa)
SrcTyrosine-protein kinase. (536 aa)
Pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (650 aa)
HnrnpuHeterogeneous nuclear ribonucleoprotein U. (813 aa)
Pinx1PIN2/TERF1-interacting telomerase inhibitor 1 isoform X2. (330 aa)
ENSMAUP00000003314annotation not available (266 aa)
Terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (405 aa)
Terf2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa)
ENSMAUP00000023853annotation not available (267 aa)
Ctc1CST complex subunit CTC1 isoform X3. (1213 aa)
Pot1Protection of telomeres protein 1. (639 aa)
Exosc10Exosome component 10. (618 aa)
Hnrnpa1Heterogeneous nuclear ribonucleoprotein A1 isoform X2. (320 aa)
Tent4bNon-canonical poly(A) RNA polymerase PAPD5 isoform X1. (685 aa)
Stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (399 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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