(81 nodes) Histone lysine methylation network (Mesocricetus auratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Kmt2d	Histone-lysine N-methyltransferase 2D isoform X11. (775 aa)
	Ash1l	Histone-lysine N-methyltransferase ASH1L. (2153 aa)
	Smyd1	SET and MYND domain containing 1. (45 aa)
	Izumo4	Izumo sperm-egg fusion protein 4 isoform X4. (227 aa)
	Paxip1	PAX-interacting protein 1 isoform X1. (1068 aa)
	Dydc1	DPY30 domain-containing protein 1. (160 aa)
	Ehmt1	Histone-lysine N-methyltransferase EHMT1 isoform X1. (1294 aa)
	Setd6	N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (472 aa)
	Kdm3a	Lysine-specific demethylase 3A. (820 aa)
	Prdm5	Zinc finger protein. (597 aa)
	Suv39h2	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (470 aa)
	ENSMAUP00000005211	annotation not available (106 aa)
	Setd4	SET domain-containing protein 4 isoform X2. (438 aa)
	Wdr5b	WD repeat-containing protein 5B. (329 aa)
	N6amt1	hemK methyltransferase family member 2. (197 aa)
	Ezh1	Histone-lysine N-methyltransferase EZH1. (747 aa)
	Pwp1	Periodic tryptophan protein 1 homolog. (500 aa)
	Ezh2	Histone-lysine N-methyltransferase EZH2 isoform X2. (745 aa)
	Setd1a	Histone-lysine N-methyltransferase SETD1A isoform X1. (1727 aa)
	Tet2	Methylcytosine dioxygenase TET2 isoform X1. (1926 aa)
	Zfp335	Zinc finger protein 335 isoform X4. (1336 aa)
	Kmt2c	Histone-lysine N-methyltransferase 2C. (756 aa)
	Pagr1	PAXIP1-associated glutamate-rich protein 1. (91 aa)
	ENSMAUP00000008408	annotation not available (106 aa)
	Rlf	Zinc finger protein Rlf isoform X2. (286 aa)
	ENSMAUP00000009202	annotation not available (164 aa)
	Smyd5	SET and MYND domain-containing protein 5. (417 aa)
	Smyd2	N-lysine methyltransferase SMYD2. (396 aa)
	Setd1b	Histone-lysine N-methyltransferase SETD1B. (88 aa)
	Suv39h1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (413 aa)
	Gcc1	GRIP and coiled-coil domain-containing protein 1. (778 aa)
	Setd7	SET domain containing 7, histone lysine methyltransferase. (208 aa)
	ENSMAUP00000011442	annotation not available (218 aa)
	Kmt5a	N-lysine methyltransferase KMT5A isoform X3. (351 aa)
	ENSMAUP00000011818	annotation not available (342 aa)
	Arid4b	AT-rich interactive domain-containing protein 4B isoform X1. (473 aa)
	Setdb2	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETDB2. (693 aa)
	Wdr5	WD repeat-containing protein 5. (334 aa)
	Setd2	Histone-lysine N-methyltransferase SETD2. (2465 aa)
	Trmt112	Multifunctional methyltransferase subunit TRM112-like protein. (125 aa)
	Ash2l	set1/Ash2 histone methyltransferase complex subunit ASH2. (346 aa)
	Men1	Menin isoform X2. (610 aa)
	Pno1	RNA-binding protein PNO1. (248 aa)
	LOC106021788	Histone-lysine N-methyltransferase SMYD3-like. (165 aa)
	ENSMAUP00000015967	annotation not available (113 aa)
	LOC101843738	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1049 aa)
	Cxxc1	CXXC-type zinc finger protein 1. (664 aa)
	Chd5	Chromodomain helicase DNA binding protein 5. (1731 aa)
	Nsd2	Histone-lysine N-methyltransferase NSD2. (1367 aa)
	Rbbp5	Retinoblastoma-binding protein 5. (532 aa)
	Setd5	LOW QUALITY PROTEIN: SET domain-containing protein 5. (1459 aa)
	Arid4a	AT-rich interactive domain-containing protein 4A. (1125 aa)
	Ctr9	RNA polymerase-associated protein CTR9 homolog. (1171 aa)
	Dmrtc2	Doublesex- and mab-3-related transcription factor C2. (370 aa)
	LOC101825348	Histone-lysine N-methyltransferase PRDM9-like. (276 aa)
	Kmt5c	Histone-lysine N-methyltransferase KMT5C isoform X2. (474 aa)
	Dpy30	Protein dpy-30 homolog. (99 aa)
	H1f2	Histone H1.2. (211 aa)
	H1f4	Histone H1.4. (219 aa)
	H1f3	Histone H1.3. (220 aa)
	Prdm8	PR domain zinc finger protein 8 isoform X1. (469 aa)
	Tet3	Methylcytosine dioxygenase TET3 isoform X1. (1802 aa)
	Nfyc	Nuclear transcription factor Y subunit gamma. (335 aa)
	Kmt5b	Histone-lysine N-methyltransferase KMT5B. (883 aa)
	Wdr61	WD repeat-containing protein 61. (305 aa)
	Rtf1	RNA polymerase-associated protein RTF1 homolog. (712 aa)
	Wdr82	WD repeat-containing protein 82. (314 aa)
	Nfya	Nuclear transcription factor Y subunit alpha isoform X1. (347 aa)
	Setmar	Histone-lysine N-methyltransferase SETMAR. (314 aa)
	Kmt2b	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (2678 aa)
	Baz2a	LOW QUALITY PROTEIN: bromodomain adjacent to zinc finger domain protein 2A. (1853 aa)
	Hdac2	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
	Ncoa6	Nuclear receptor coactivator 6 isoform X4. (507 aa)
	Nfyb	Nuclear transcription factor Y subunit beta isoform X1. (207 aa)
	Dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1545 aa)
	Bend3	BEN domain-containing protein 3. (825 aa)
	Kmt2a	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3946 aa)
	Setdb1	Histone-lysine N-methyltransferase SETDB1. (1133 aa)
	Kiaa2013	Uncharacterized protein KIAA2013 homolog. (634 aa)
	Ehmt2	Histone-lysine N-methyltransferase EHMT2 isoform X2. (1249 aa)
	Dydc2	DPY30 domain-containing protein 2. (139 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arid4a	Arid4b	ENSMAUP00000017294	ENSMAUP00000012508	AT-rich interactive domain-containing protein 4A.	AT-rich interactive domain-containing protein 4B isoform X1.	0.704
Arid4a	Ash1l	ENSMAUP00000017294	ENSMAUP00000000929	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase ASH1L.	0.677
Arid4a	Chd5	ENSMAUP00000017294	ENSMAUP00000016543	AT-rich interactive domain-containing protein 4A.	Chromodomain helicase DNA binding protein 5.	0.775
Arid4a	Cxxc1	ENSMAUP00000017294	ENSMAUP00000016403	AT-rich interactive domain-containing protein 4A.	CXXC-type zinc finger protein 1.	0.617
Arid4a	ENSMAUP00000005211	ENSMAUP00000017294	ENSMAUP00000005211	AT-rich interactive domain-containing protein 4A.	annotation not available	0.416
Arid4a	Ehmt1	ENSMAUP00000017294	ENSMAUP00000003947	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase EHMT1 isoform X1.	0.449
Arid4a	Ehmt2	ENSMAUP00000017294	ENSMAUP00000025082	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase EHMT2 isoform X2.	0.449
Arid4a	Ezh1	ENSMAUP00000017294	ENSMAUP00000005924	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase EZH1.	0.477
Arid4a	Ezh2	ENSMAUP00000017294	ENSMAUP00000007033	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase EZH2 isoform X2.	0.477
Arid4a	Hdac2	ENSMAUP00000017294	ENSMAUP00000023187	AT-rich interactive domain-containing protein 4A.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.943
Arid4a	Kmt2a	ENSMAUP00000017294	ENSMAUP00000024304	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.432
Arid4a	Kmt2b	ENSMAUP00000017294	ENSMAUP00000023044	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.432
Arid4a	Kmt5a	ENSMAUP00000017294	ENSMAUP00000011745	AT-rich interactive domain-containing protein 4A.	N-lysine methyltransferase KMT5A isoform X3.	0.486
Arid4a	LOC101825348	ENSMAUP00000017294	ENSMAUP00000018351	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase PRDM9-like.	0.416
Arid4a	LOC106021788	ENSMAUP00000017294	ENSMAUP00000015707	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase SMYD3-like.	0.432
Arid4a	Nsd2	ENSMAUP00000017294	ENSMAUP00000016644	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase NSD2.	0.493
Arid4a	Prdm5	ENSMAUP00000017294	ENSMAUP00000005011	AT-rich interactive domain-containing protein 4A.	Zinc finger protein.	0.416
Arid4a	Rlf	ENSMAUP00000017294	ENSMAUP00000009191	AT-rich interactive domain-containing protein 4A.	Zinc finger protein Rlf isoform X2.	0.416
Arid4a	Setd1a	ENSMAUP00000017294	ENSMAUP00000007225	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase SETD1A isoform X1.	0.555
Arid4a	Setd1b	ENSMAUP00000017294	ENSMAUP00000010288	AT-rich interactive domain-containing protein 4A.	Histone-lysine N-methyltransferase SETD1B.	0.555

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