STRINGSTRING
Dhrs9 Dhrs9 Cyp21a1 Cyp21a1 Scp2 Scp2 Akr1c14 Akr1c14 Akr1c18 Akr1c18 Cyp17a1 Cyp17a1 Cyp46a1 Cyp46a1 Afp Afp LOC101839651 LOC101839651 LOC101835654 LOC101835654 LOC101843587 LOC101843587 LOC101843311 LOC101843311 ENSMAUP00000023469 ENSMAUP00000023469 Srd5a1 Srd5a1 Stard3 Stard3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dhrs9Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
Cyp21a1Steroid 21-hydroxylase isoform X2; Belongs to the cytochrome P450 family. (496 aa)
Scp2Non-specific lipid-transfer protein isoform X2; Belongs to the thiolase-like superfamily. Thiolase family. (231 aa)
Akr1c143-alpha-hydroxysteroid dehydrogenase-like isoform X1. (323 aa)
Akr1c18Aldo-keto reductase family 1 member C18 isoform X1. (323 aa)
Cyp17a1Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (431 aa)
Cyp46a1Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa)
AfpAlpha-fetoprotein. (609 aa)
LOC101839651Aldo-keto reductase family 1 member C21-like. (310 aa)
LOC101835654Signal transducer and activator of transcription. (228 aa)
LOC101843587Aldo-keto reductase family 1 member C21-like isoform X1. (319 aa)
LOC1018433113-hydroxyhexobarbital dehydrogenase 1/3-alpha, 17-beta-hydroxysteroid dehydrogenase. (323 aa)
ENSMAUP00000023469annotation not available (143 aa)
Srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
Stard3stAR-related lipid transfer protein 3. (442 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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