STRINGSTRING
Hoxd3 Hoxd3 Impact Impact Cxcl12 Cxcl12 Lin28a Lin28a ENSMAUP00000021256 ENSMAUP00000021256 Foxg1 Foxg1 Sall1 Sall1 Cdon Cdon ENSMAUP00000022544 ENSMAUP00000022544 Mmd2 Mmd2 Hmg20b Hmg20b Ascl1 Ascl1 Duoxa1 Duoxa1 Bdnf Bdnf Eif4g1 Eif4g1 Epo Epo Dlx1 Dlx1 Sin3a Sin3a Dlx2 Dlx2 Heyl Heyl Phox2b Phox2b Pcp4 Pcp4 Dmd-2 Dmd-2 Vwc2 Vwc2 Itgb1 Itgb1 Ccr5 Ccr5 Zeb1 Zeb1 Dmd Dmd Kdm4c Kdm4c Bmp4 Bmp4 App App Ngf Ngf Neurog2 Neurog2 Dkk1 Dkk1 Pten Pten Neurod2 Neurod2 Gata2 Gata2 Nkx2-5 Nkx2-5 Sh3gl3 Sh3gl3 Map1b Map1b ENSMAUP00000006919 ENSMAUP00000006919 Gli2 Gli2 Vwc2l Vwc2l Ect2 Ect2 Prox1 Prox1 Mmd Mmd Pax6 Pax6 Brinp3 Brinp3 Adra2c Adra2c Tle6 Tle6 Kctd11 Kctd11 Bcl6 Bcl6 Neurog3 Neurog3 Mapk8ip3 Mapk8ip3 Bmp6 Bmp6 Gdf5 Gdf5 Socs2 Socs2 Gdf7 Gdf7 Trpc5 Trpc5 Kdm4a Kdm4a Prpf19 Prpf19 Timp2 Timp2 Gdf6 Gdf6 Foxa1 Foxa1 LOC106022581 LOC106022581 Arhgef2 Arhgef2 Brinp1 Brinp1 Actr3 Actr3 Nbl1 Nbl1 Trim32 Trim32 Rara Rara Trpc6 Trpc6 Rnf112 Rnf112 Bend6 Bend6 Fgf2 Fgf2 Fezf1 Fezf1 Bmp2 Bmp2 Mef2c Mef2c Tcf4 Tcf4 Bmp7 Bmp7 Fez1 Fez1 Neurod1 Neurod1 Zc4h2 Zc4h2 Atoh1 Atoh1 Tcf3 Tcf3 Fezf2 Fezf2 Brinp2 Brinp2 Foxa2 Foxa2 Shh Shh Etv5 Etv5 Sox11 Sox11 Ncoa1 Ncoa1 Gprc5b Gprc5b Nap1l2 Nap1l2 Sox2 Sox2 Neurog1 Neurog1 Irx3 Irx3 Il6 Il6 LOC101839191 LOC101839191 LOC101837855 LOC101837855 Fgfr1 Fgfr1 Tgif1 Tgif1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hoxd3Homeobox protein Hox-D3. (432 aa)
ImpactProtein IMPACT. (310 aa)
Cxcl12Stromal cell-derived factor 1 isoform X1. (119 aa)
Lin28aProtein lin-28 homolog A. (209 aa)
ENSMAUP00000021256annotation not available (277 aa)
Foxg1Forkhead box protein G1. (484 aa)
Sall1Sal-like protein 1. (1318 aa)
CdonCell adhesion molecule-related/down-regulated by oncogenes isoform X1. (1254 aa)
ENSMAUP00000022544annotation not available (130 aa)
Mmd2Monocyte to macrophage differentiation factor 2. (243 aa)
Hmg20bHigh mobility group 20B. (317 aa)
Ascl1Achaete-scute homolog 1. (234 aa)
Duoxa1Dual oxidase maturation factor 1. (341 aa)
BdnfBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (287 aa)
Eif4g1Eukaryotic Translation initiation factor 4 gamma 1. (1149 aa)
EpoErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
Dlx1Homeobox protein DLX-1. (255 aa)
Sin3aPaired amphipathic helix protein Sin3a. (1076 aa)
Dlx2Homeobox protein DLX-2. (331 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
Phox2bPaired mesoderm homeobox protein 2B. (186 aa)
Pcp4Purkinje cell protein 4. (62 aa)
Dmd-2Dystrophin isoform X3. (770 aa)
Vwc2Brorin. (325 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (92 aa)
Ccr5C-C chemokine receptor type 5 isoform X2; Belongs to the G-protein coupled receptor 1 family. (354 aa)
Zeb1Zinc finger E-box-binding homeobox 1; Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'- CANNTG-3'). Promotes tumorige [...] (1043 aa)
DmdDystrophin isoform X7. (617 aa)
Kdm4cLysine-specific demethylase 4C. (371 aa)
Bmp4Bone morphogenetic protein 4. (409 aa)
AppAmyloid beta A4 protein. (751 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
Neurog2Neurogenin-2. (267 aa)
Dkk1Dickkopf-related protein 1. (269 aa)
PtenPhosphatase and tensin homolog. (403 aa)
Neurod2Neurogenic differentiation factor. (382 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Nkx2-5Homeobox protein Nkx-2.5. (317 aa)
Sh3gl3endophilin-A3 isoform X1. (347 aa)
Map1bMicrotubule-associated protein 1B. (236 aa)
ENSMAUP00000006919annotation not available (209 aa)
Gli2Zinc finger protein GLI2. (1544 aa)
Vwc2lVon Willebrand factor C domain-containing protein 2-like. (222 aa)
Ect2Protein ECT2 isoform X1. (912 aa)
Prox1Prospero homeobox protein 1 isoform X2. (734 aa)
MmdMonocyte to macrophage differentiation factor. (242 aa)
Pax6Paired box protein Pax-6 isoform X1. (436 aa)
Brinp3BMP/retinoic acid-inducible neural-specific protein 3. (766 aa)
Adra2calpha-2C adrenergic receptor. (458 aa)
Tle6Transducin-like enhancer protein 6 isoform X1. (523 aa)
Kctd11BTB/POZ domain-containing protein KCTD11. (232 aa)
Bcl6B-cell lymphoma 6 protein. (707 aa)
Neurog3Neurogenin-3. (214 aa)
Mapk8ip3C-Jun-amino-terminal kinase-interacting protein 3. (1337 aa)
Bmp6Bone morphogenetic protein 6. (502 aa)
Gdf5Growth/differentiation factor 5. (495 aa)
Socs2Suppressor of cytokine signaling 2. (198 aa)
Gdf7Growth/differentiation factor 7. (442 aa)
Trpc5Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (963 aa)
Kdm4aLysine-specific demethylase 4A. (1063 aa)
Prpf19pre-mRNA-processing factor 19 isoform X1. (523 aa)
Timp2Metalloproteinase inhibitor 2. (220 aa)
Gdf6Growth/differentiation factor 6. (451 aa)
Foxa1Hepatocyte nuclear factor 3-alpha. (460 aa)
LOC106022581Microtubule-associated protein 1B-like. (120 aa)
Arhgef2Rho guanine nucleotide exchange factor 2 isoform X7. (284 aa)
Brinp1BMP/retinoic acid-inducible neural-specific protein 1. (760 aa)
Actr3Actin related protein 3. (161 aa)
Nbl1Neuroblastoma suppressor of tumorigenicity 1 isoform X1. (180 aa)
Trim32E3 ubiquitin-protein ligase TRIM32. (655 aa)
RaraRetinoic acid receptor alpha isoform X1. (462 aa)
Trpc6Short transient receptor potential channel 6; Belongs to the transient receptor (TC 1.A.4) family. (928 aa)
Rnf112RING finger protein 112 isoform X2. (672 aa)
Bend6BEN domain-containing protein 6 isoform X1. (279 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Fezf1Fez family zinc finger protein 1. (475 aa)
Bmp2Bone morphogenetic protein 2 isoform X1. (394 aa)
Mef2cMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
Tcf4Transcription factor 4. (670 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Fez1Fasciculation and elongation protein zeta-1. (401 aa)
Neurod1Neurogenic differentiation factor 1; Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or [...] (355 aa)
Zc4h2Zinc finger C4H2 domain-containing protein isoform X2. (224 aa)
Atoh1Protein atonal homolog 1. (351 aa)
Tcf3Transcription factor E2-alpha; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region (By similarity). (633 aa)
Fezf2Fez family zinc finger protein 2. (455 aa)
Brinp2BMP/retinoic acid-inducible neural-specific protein 2. (783 aa)
Foxa2Hepatocyte nuclear factor 3-beta isoform X2. (460 aa)
ShhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (439 aa)
Etv5ETS translocation variant 5 isoform X1. (528 aa)
Sox11Transcription factor SOX. (395 aa)
Ncoa1Nuclear receptor coactivator. (1444 aa)
Gprc5bG-protein coupled receptor family C group 5 member B isoform X2. (411 aa)
Nap1l2Nucleosome assembly protein 1-like 2; Belongs to the nucleosome assembly protein (NAP) family. (462 aa)
Sox2Transcription factor SOX-2. (319 aa)
Neurog1Neurogenin-1. (241 aa)
Irx3Iroquois-class homeodomain protein IRX-3. (507 aa)
Il6Interleukin-6. (212 aa)
LOC101839191RE1-silencing transcription factor-like. (301 aa)
LOC101837855C-Jun-amino-terminal kinase-interacting protein 4-like. (466 aa)
Fgfr1Fibroblast growth factor receptor. (819 aa)
Tgif1Homeobox protein TGIF1 isoform X1. (58 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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