STRINGSTRING
Akt3 Akt3 Edn1 Edn1 Rapgef3 Rapgef3 Kdm1a Kdm1a Atp7a Atp7a ENSMAUP00000025330 ENSMAUP00000025330 ENSMAUP00000025679 ENSMAUP00000025679 ENSMAUP00000015967 ENSMAUP00000015967 Tmem123 Tmem123 Cdk4 Cdk4 Tp73 Tp73 ENSMAUP00000009202 ENSMAUP00000009202 Prr16 Prr16 ENSMAUP00000008492 ENSMAUP00000008492 Slc26a5 Slc26a5 Rb1cc1 Rb1cc1 Rb1cc1-2 Rb1cc1-2 Ret Ret ENSMAUP00000004541 ENSMAUP00000004541 Ahr Ahr LOC101843738 LOC101843738 Hsp90ab1 Hsp90ab1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Edn1Endothelin-1. (202 aa)
Rapgef3Rap guanine nucleotide exchange factor 3 isoform X4. (926 aa)
Kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (870 aa)
Atp7aCopper-transporting ATPase 1. (1491 aa)
ENSMAUP00000025330annotation not available (154 aa)
ENSMAUP00000025679annotation not available (108 aa)
ENSMAUP00000015967annotation not available (113 aa)
Tmem123LOW QUALITY PROTEIN: porimin. (106 aa)
Cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (286 aa)
ENSMAUP00000009202annotation not available (164 aa)
Prr16Protein Largen isoform X1. (304 aa)
ENSMAUP00000008492annotation not available (391 aa)
Slc26a5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (742 aa)
Rb1cc1RB1 inducible coiled-coil 1. (164 aa)
Rb1cc1-2RB1-inducible coiled-coil protein 1 isoform X2. (227 aa)
RetProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
ENSMAUP00000004541annotation not available (622 aa)
AhrAryl hydrocarbon receptor. (731 aa)
LOC101843738UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1049 aa)
Hsp90ab1Heat shock protein HSP 90-beta. (724 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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