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Srd5a1 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa) | ||||
Srd5a2 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (253 aa) | ||||
Srd5a3 | Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5- alpha-dihydrotestosterone (DHT) (By similarity). (328 aa) |