STRINGSTRING
Ncoa3 Ncoa3 Igf1r Igf1r Cdc14a Cdc14a E2f7 E2f7 Dr1 Dr1 ENSMAUP00000009809 ENSMAUP00000009809 Ccp110 Ccp110 Cul3 Cul3 Smyd5 Smyd5 Aspm Aspm Pdgfb Pdgfb Sgf29 Sgf29 Drd2 Drd2 Calm3 Calm3 Rack1 Rack1 Fgf1 Fgf1 Spast Spast Rab11fip4 Rab11fip4 Fgfr2 Fgfr2 Aurkc Aurkc Cat Cat Dll1 Dll1 Txnip Txnip Pdgfd Pdgfd Pou5f1 Pou5f1 ENSMAUP00000012811 ENSMAUP00000012811 Sox17 Sox17 ENSMAUP00000012933 ENSMAUP00000012933 Wdr5 Wdr5 Plk1 Plk1 Ankrd53 Ankrd53 Prc1 Prc1 ENSMAUP00000013084 ENSMAUP00000013084 Gipc2 Gipc2 Fsd1l Fsd1l Cdc25b Cdc25b Incenp Incenp Setd2 Setd2 Apc Apc Fgf7 Fgf7 Prdm15 Prdm15 Vegfb Vegfb Sfrp2 Sfrp2 Cit Cit Insc Insc Ereg Ereg Racgap1 Racgap1 ENSMAUP00000014236 ENSMAUP00000014236 Men1 Men1 Klhl13 Klhl13 Fsd1 Fsd1 Fgf2 Fgf2 Rbl2 Rbl2 Kif20a Kif20a Tada3 Tada3 Calm1 Calm1 Vegfc Vegfc Uvrag Uvrag Pik3r4 Pik3r4 Pdxp Pdxp Kdf1 Kdf1 Evi2b Evi2b Kif18b Kif18b Pdgfa Pdgfa Gipc3 Gipc3 Mllt3 Mllt3 Tex14 Tex14 Klhl21 Klhl21 Vps4a Vps4a Nkx3-1 Nkx3-1 Zbtb18 Zbtb18 Prpf40a Prpf40a Garem2 Garem2 Aurkb Aurkb Nup62 Nup62 Brca2 Brca2 Zfyve19 Zfyve19 Pkp4 Pkp4 Cspp1 Cspp1 Igf2 Igf2 Calm2 Calm2 Fgf9 Fgf9 Ptch1 Ptch1 Birc6 Birc6 ENSMAUP00000015826 ENSMAUP00000015826 Htr2b Htr2b Pdgfc Pdgfc Kat2a Kat2a Hoxc4 Hoxc4 Sirt2 Sirt2 ENSMAUP00000020843 ENSMAUP00000020843 Rab11a Rab11a Il1a Il1a Plk3 Plk3 Kif13a Kif13a Poldip2 Poldip2 Cdk2ap2 Cdk2ap2 Git1 Git1 Tgfa Tgfa Fgf3 Fgf3 Flcn Flcn Il1b Il1b Wnt9b Wnt9b LOC101832350 LOC101832350 Mbip Mbip Nap1l2 Nap1l2 Entr1 Entr1 Fgf5 Fgf5 Ybx1 Ybx1 LOC110342606 LOC110342606 Kif3b Kif3b Shh Shh Intu Intu Fgf8 Fgf8 ENSMAUP00000017409 ENSMAUP00000017409 Susd2 Susd2 Vegfd Vegfd Pkn2-2 Pkn2-2 Map9 Map9 Prkce Prkce Esrrb Esrrb Pin1 Pin1 Cib1 Cib1 Pgf Pgf ENSMAUP00000001477 ENSMAUP00000001477 Tal1 Tal1 CUNH10orf99 CUNH10orf99 Yeats2 Yeats2 Cenpv Cenpv Cdc14b Cdc14b Kat14 Kat14 Kif20b Kif20b Tgfb1 Tgfb1 Bcl2l1 Bcl2l1 Cetn2 Cetn2 Rbl1 Rbl1 Cdc6 Cdc6 Cdc42 Cdc42 Tgfb3 Tgfb3 Rxfp3 Rxfp3 LOC101831792 LOC101831792 Becn1 Becn1 Mdk Mdk Chmp4c Chmp4c Vegfa Vegfa Sstr5 Sstr5 Ahctf1 Ahctf1 Zfyve26 Zfyve26 Myc Myc ENSMAUP00000006088 ENSMAUP00000006088 Sh3glb1 Sh3glb1 Sfn Sfn Plk4 Plk4 Aurka Aurka Tas1r2 Tas1r2 Tp63 Tp63 Orc6 Orc6 Myo19 Myo19 Mpl Mpl Plk5 Plk5 Pik3c3 Pik3c3 Blm Blm ENSMAUP00000007276 ENSMAUP00000007276 Bbs4 Bbs4 Hdgf Hdgf Chmp3 Chmp3 Plk2 Plk2 E2f8 E2f8 Tada2a Tada2a Thbs4 Thbs4 Ect2 Ect2 Ptn Ptn Pax6 Pax6 Gipc1 Gipc1 Cxcr5 Cxcr5 Pkn2 Pkn2 Kif23 Kif23 LOC101838729 LOC101838729 Tgfb2 Tgfb2 Zzz3 Zzz3 Efhc1 Efhc1 Drd3 Drd3 Tle6 Tle6 ENSMAUP00000009408 ENSMAUP00000009408 Prok1 Prok1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ncoa3Nuclear receptor coactivator. (1409 aa)
Igf1rTyrosine-protein kinase receptor. (1154 aa)
Cdc14aDual specificity protein phosphatase CDC14A isoform X1. (625 aa)
E2f7Transcription factor E2F7. (900 aa)
Dr1Protein Dr1. (176 aa)
ENSMAUP00000009809annotation not available (84 aa)
Ccp110Centriolar coiled-coil protein of 110 kDa isoform X1. (198 aa)
Cul3Cullin-3; Belongs to the cullin family. (761 aa)
Smyd5SET and MYND domain-containing protein 5. (417 aa)
AspmAbnormal spindle-like microcephaly-associated protein. (3033 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (221 aa)
Sgf29SAGA-associated factor 29 isoform X2. (293 aa)
Drd2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (444 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
Rack1Receptor of activated protein C kinase 1. (147 aa)
Fgf1Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with int [...] (155 aa)
SpastSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (586 aa)
Rab11fip4Rab11 family-interacting protein 4 isoform X1. (637 aa)
Fgfr2Fibroblast growth factor receptor. (784 aa)
AurkcAurora kinase C. (118 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (733 aa)
TxnipThioredoxin-interacting protein. (394 aa)
PdgfdPlatelet-derived growth factor D. (313 aa)
Pou5f1POU domain protein. (358 aa)
ENSMAUP00000012811annotation not available (405 aa)
Sox17Transcription factor SOX-17. (185 aa)
ENSMAUP00000012933annotation not available (541 aa)
Wdr5WD repeat-containing protein 5. (334 aa)
Plk1Serine/threonine-protein kinase PLK. (602 aa)
Ankrd53Ankyrin repeat domain-containing protein 53. (497 aa)
Prc1Protein regulator of cytokinesis 1. (561 aa)
ENSMAUP00000013084annotation not available (169 aa)
Gipc2PDZ domain-containing protein GIPC2. (314 aa)
Fsd1lFSD1-like protein isoform X1. (498 aa)
Cdc25bM-phase inducer phosphatase 2. (575 aa)
IncenpInner centromere protein isoform X4. (817 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2465 aa)
ApcAdenomatous polyposis coli protein isoform X4. (492 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Prdm15PR domain zinc finger protein 15 isoform X1. (1175 aa)
VegfbVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (201 aa)
Sfrp2Secreted frizzled-related protein 2 precursor. (295 aa)
CitCitron Rho-interacting kinase isoform X1. (1618 aa)
InscProtein inscuteable homolog isoform X1. (579 aa)
EregProepiregulin. (162 aa)
Racgap1Rac GTPase-activating protein 1. (131 aa)
ENSMAUP00000014236annotation not available (114 aa)
Men1Menin isoform X2. (610 aa)
Klhl13Kelch-like protein 13 isoform X3. (655 aa)
Fsd1Fibronectin type III and SPRY domain-containing protein 1. (496 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Rbl2Retinoblastoma-like protein 2 isoform X2. (1134 aa)
Kif20aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (885 aa)
Tada3Transcriptional adapter 3. (371 aa)
Calm1Calmodulin 1. (149 aa)
VegfcVascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (415 aa)
UvragUV radiation resistance-associated gene protein. (686 aa)
Pik3r4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
PdxpPyridoxal phosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (293 aa)
Kdf1Keratinocyte differentiation factor 1. (397 aa)
Evi2bProtein EVI2B. (445 aa)
Kif18bKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (834 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (211 aa)
Gipc3PDZ domain-containing protein GIPC3 isoform X4. (296 aa)
Mllt3Protein AF-9 isoform X1. (572 aa)
Tex14Inactive serine/threonine-protein kinase TEX14. (1404 aa)
Klhl21Kelch-like protein 21. (597 aa)
Vps4aVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (439 aa)
Nkx3-1Homeobox protein Nkx-3.1. (239 aa)
Zbtb18Zinc finger and BTB domain-containing protein 18 isoform X1. (531 aa)
Prpf40apre-mRNA-processing factor 40 homolog A isoform X2. (953 aa)
Garem2GRB2-associated and regulator of MAPK protein 2. (877 aa)
AurkbAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (339 aa)
Nup62Nuclear pore glycoprotein p62. (517 aa)
Brca2LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein. (1176 aa)
Zfyve19abscission/NoCut checkpoint regulator isoform X1. (392 aa)
Pkp4Plakophilin-4 isoform X5. (1190 aa)
Cspp1Centrosome and spindle pole-associated protein 1 isoform X3. (1202 aa)
Igf2Insulin-like growth factor II isoform X1. (191 aa)
Calm2Calmodulin 2. (149 aa)
Fgf9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
Ptch1Protein patched homolog 1. (1440 aa)
Birc6Baculoviral IAP repeat-containing protein 6. (4829 aa)
ENSMAUP00000015826annotation not available (113 aa)
Htr2b5-hydroxytryptamine receptor 2B. (480 aa)
PdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
Kat2aHistone acetyltransferase KAT2A isoform X2. (838 aa)
Hoxc4Homeobox protein Hox-C4. (264 aa)
Sirt2NAD-dependent protein deacetylase sirtuin-2. (342 aa)
ENSMAUP00000020843annotation not available (239 aa)
Rab11aRas-related protein Rab-11A. (216 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (269 aa)
Plk3Serine/threonine-protein kinase PLK. (648 aa)
Kif13aKinesin-like protein KIF13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1456 aa)
Poldip2Polymerase delta-interacting protein 2. (368 aa)
Cdk2ap2Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (127 aa)
Git1ARF GTPase-activating protein GIT1. (770 aa)
TgfaProtransforming growth factor alpha. (159 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
FlcnFolliculin. (466 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LOC101832350Aurora kinase C-like. (108 aa)
MbipMAP3K12-binding inhibitory protein 1 isoform X1. (338 aa)
Nap1l2Nucleosome assembly protein 1-like 2; Belongs to the nucleosome assembly protein (NAP) family. (462 aa)
Entr1Serologically defined colon cancer antigen 3 isoform X1. (433 aa)
Fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
Ybx1Nuclease-sensitive element-binding protein 1. (303 aa)
LOC110342606Citron Rho-interacting kinase-like. (172 aa)
Kif3bKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
ShhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (439 aa)
IntuProtein inturned isoform X1. (938 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
ENSMAUP00000017409annotation not available (348 aa)
Susd2Sushi domain-containing protein 2 isoform X2. (820 aa)
VegfdVascular endothelial growth factor D isoform X3; Belongs to the PDGF/VEGF growth factor family. (358 aa)
Pkn2-2Serine/threonine-protein kinase N2. (484 aa)
Map9Microtubule-associated protein 9. (644 aa)
PrkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (623 aa)
EsrrbEstrogen-related receptor gamma. (367 aa)
Pin1Peptidyl-prolyl cis-trans isomerase. (165 aa)
Cib1Calcium and integrin-binding protein 1. (191 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (158 aa)
ENSMAUP00000001477annotation not available (69 aa)
Tal1T-cell acute lymphocytic leukemia protein 1. (183 aa)
CUNH10orf99Secreted protein C10orf99 homolog. (78 aa)
Yeats2YEATS domain-containing protein 2. (1256 aa)
CenpvCentromere protein V. (252 aa)
Cdc14bDual specificity protein phosphatase CDC14B. (481 aa)
Kat14Cysteine-rich protein 2-binding protein. (740 aa)
Kif20bKinesin-like protein KIF20B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1773 aa)
Tgfb1Transforming growth factor beta-1. (286 aa)
Bcl2l1Bcl-2-like protein 1. (233 aa)
Cetn2Centrin-2. (172 aa)
Rbl1Retinoblastoma-like protein 1 isoform X1. (1063 aa)
Cdc6Cell division control protein 6 homolog isoform X2. (418 aa)
Cdc42Cell division control protein 42 homolog isoform X1. (191 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Rxfp3Relaxin-3 receptor 1. (477 aa)
LOC101831792LOW QUALITY PROTEIN: mas-related G-protein coupled receptor member B2-like; Belongs to the G-protein coupled receptor 1 family. (320 aa)
Becn1Beclin-1 isoform X1. (456 aa)
MdkMidkine. (143 aa)
Chmp4cCharged multivesicular body protein 4c. (98 aa)
VegfaVascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (248 aa)
Sstr5Somatostatin receptor type 5; Belongs to the G-protein coupled receptor 1 family. (362 aa)
Ahctf1Protein ELYS isoform X1. (2243 aa)
Zfyve26Zinc finger FYVE domain-containing protein 26. (2278 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
ENSMAUP00000006088annotation not available (179 aa)
Sh3glb1endophilin-B1. (194 aa)
Sfn14-3-3 protein sigma; Belongs to the 14-3-3 family. (247 aa)
Plk4Serine/threonine-protein kinase PLK4 isoform X1. (927 aa)
AurkaAurora kinase A; Belongs to the protein kinase superfamily. (401 aa)
Tas1r2Taste receptor type 1 member 2. (843 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
Orc6Origin recognition complex subunit 6. (253 aa)
Myo19Unconventional myosin-XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (930 aa)
MplThrombopoietin receptor isoform X1. (388 aa)
Plk5Inactive serine/threonine-protein kinase PLK5. (579 aa)
Pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (898 aa)
BlmBloom syndrome protein. (1415 aa)
ENSMAUP00000007276annotation not available (359 aa)
Bbs4Bardet-Biedl syndrome 4 protein. (517 aa)
HdgfHepatoma-derived growth factor isoform X2. (130 aa)
Chmp3Charged multivesicular body protein 3. (197 aa)
Plk2Serine/threonine-protein kinase PLK. (682 aa)
E2f8Transcription factor E2F8. (861 aa)
Tada2aTranscriptional adapter. (389 aa)
Thbs4Thrombospondin-4. (867 aa)
Ect2Protein ECT2 isoform X1. (912 aa)
PtnPleiotrophin. (168 aa)
Pax6Paired box protein Pax-6 isoform X1. (436 aa)
Gipc1PDZ domain-containing protein GIPC1. (333 aa)
Cxcr5C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
Pkn2Protein kinase N2. (60 aa)
Kif23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (843 aa)
LOC101838729THO complex subunit 5 homolog isoform X1. (348 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
Zzz3ZZ-type zinc finger-containing protein 3 isoform X2. (421 aa)
Efhc1EF-hand domain-containing protein 1. (648 aa)
Drd3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (447 aa)
Tle6Transducin-like enhancer protein 6 isoform X1. (523 aa)
ENSMAUP00000009408annotation not available (808 aa)
Prok1Prokineticin-1. (66 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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