STRINGSTRING
Rbp4 Rbp4 Rbpj Rbpj Bmp10 Bmp10 Hdac2 Hdac2 Cdk1 Cdk1 Ncam1 Ncam1 Erbb4 Erbb4 ENSMAUP00000025330 ENSMAUP00000025330 Nkx2-5 Nkx2-5 Nog Nog LOC101836961 LOC101836961 Tp73 Tp73 Gli1 Gli1 Fgf20 Fgf20 Vgll4 Vgll4 Hey2 Hey2 Fgfr2 Fgfr2 Wnt2 Wnt2 Tgfbr1 Tgfbr1 Apc Apc Cxadr Cxadr Gata4 Gata4 Fgf2 Fgf2 Mef2c Mef2c Mapk14 Mapk14 Bmpr1a Bmpr1a Ccnd2 Ccnd2 Mapk1 Mapk1 Tbx5 Tbx5 Foxp1 Foxp1 Mapk11 Mapk11 LOC101836687 LOC101836687 Meis1 Meis1 Tgfbr2 Tgfbr2 Tgfbr3 Tgfbr3 Cited2 Cited2 Gata6 Gata6 Kcnk2 Kcnk2 Tbx2 Tbx2 Pten Pten Gja1 Gja1 Tbx20 Tbx20 Zfpm2 Zfpm2 Jarid2 Jarid2 Fgf9 Fgf9 Sav1 Sav1 Fgfr1 Fgfr1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rbp4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
RbpjRecombining binding protein suppressor of hairless isoform X1. (526 aa)
Bmp10Bone morphogenetic protein 10. (423 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
Cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
Ncam1Neural cell adhesion molecule 1 isoform X5. (851 aa)
Erbb4Receptor protein-tyrosine kinase. (1308 aa)
ENSMAUP00000025330annotation not available (154 aa)
Nkx2-5Homeobox protein Nkx-2.5. (317 aa)
NogNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC101836961Serine/threonine-protein kinase pim-1. (313 aa)
Tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (286 aa)
Gli1Zinc finger protein GLI1. (981 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
Vgll4Transcription cofactor vestigial-like protein 4 isoform X1. (287 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
Fgfr2Fibroblast growth factor receptor. (784 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
ApcAdenomatous polyposis coli protein isoform X4. (492 aa)
CxadrCoxsackievirus and adenovirus receptor isoform X1. (365 aa)
Gata4Transcription factor GATA-4 isoform X2. (443 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Mef2cMyocyte-specific enhancer factor 2C isoform X4. (483 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Ccnd2G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Tbx5T-box transcription factor TBX5. (518 aa)
Foxp1Forkhead box protein P1 isoform X4. (694 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
LOC101836687Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
Meis1Homeobox protein Meis1 isoform X1. (465 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Tgfbr3Transforming growth factor beta receptor type 3. (741 aa)
Cited2Cbp/p300-interacting transactivator 2. (269 aa)
Gata6Transcription factor GATA-6. (442 aa)
Kcnk2Potassium channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
Tbx2T-box transcription factor TBX2. (714 aa)
PtenPhosphatase and tensin homolog. (403 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
Tbx20T-box transcription factor TBX20. (445 aa)
Zfpm2Zinc finger protein ZFPM2 isoform X1. (1156 aa)
Jarid2Protein Jumonji isoform X1. (1234 aa)
Fgf9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
Sav1Protein salvador homolog 1. (387 aa)
Fgfr1Fibroblast growth factor receptor. (819 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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