node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cacna2d1 | Scn5a | ENSMAUP00000003629 | ENSMAUP00000015795 | Voltage-dependent calcium channel subunit alpha-2/delta-1. | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.796 |
Cav3 | Gja1 | ENSMAUP00000021421 | ENSMAUP00000004854 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.547 |
Cav3 | Kcnh2 | ENSMAUP00000021421 | ENSMAUP00000011215 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Potassium voltage-gated channel subfamily H member 2 isoform X1. | 0.524 |
Cav3 | Scn4b | ENSMAUP00000021421 | ENSMAUP00000001448 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Sodium channel subunit beta-4. | 0.457 |
Cav3 | Scn5a | ENSMAUP00000021421 | ENSMAUP00000015795 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.628 |
Cav3 | Snta1 | ENSMAUP00000021421 | ENSMAUP00000014144 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Alpha-1-syntrophin. | 0.597 |
ENSMAUP00000001689 | Scn4b | ENSMAUP00000001689 | ENSMAUP00000001448 | annotation not available | Sodium channel subunit beta-4. | 0.465 |
ENSMAUP00000001689 | Scn5a | ENSMAUP00000001689 | ENSMAUP00000015795 | annotation not available | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.567 |
ENSMAUP00000010641 | Scn5a | ENSMAUP00000010641 | ENSMAUP00000015795 | annotation not available | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.764 |
Gja1 | Cav3 | ENSMAUP00000004854 | ENSMAUP00000021421 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.547 |
Gja1 | Gja5 | ENSMAUP00000004854 | ENSMAUP00000017843 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.801 |
Gja1 | Scn5a | ENSMAUP00000004854 | ENSMAUP00000015795 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.534 |
Gja5 | Gja1 | ENSMAUP00000017843 | ENSMAUP00000004854 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | 0.801 |
Gja5 | Kcnq1 | ENSMAUP00000017843 | ENSMAUP00000023205 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. | 0.448 |
Gja5 | Scn5a | ENSMAUP00000017843 | ENSMAUP00000015795 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.548 |
Kcne1 | Kcne3 | ENSMAUP00000005860 | ENSMAUP00000010617 | Potassium voltage-gated channel subfamily E member 1 isoform X1. | Potassium voltage-gated channel subfamily E member 3. | 0.759 |
Kcne1 | Kcne5 | ENSMAUP00000005860 | ENSMAUP00000002780 | Potassium voltage-gated channel subfamily E member 1 isoform X1. | Potassium voltage-gated channel subfamily E regulatory beta subunit 5. | 0.424 |
Kcne1 | Kcnh2 | ENSMAUP00000005860 | ENSMAUP00000011215 | Potassium voltage-gated channel subfamily E member 1 isoform X1. | Potassium voltage-gated channel subfamily H member 2 isoform X1. | 0.768 |
Kcne1 | Kcnh6 | ENSMAUP00000005860 | ENSMAUP00000016313 | Potassium voltage-gated channel subfamily E member 1 isoform X1. | Potassium voltage-gated channel subfamily H member 6. | 0.645 |
Kcne1 | Kcnq1 | ENSMAUP00000005860 | ENSMAUP00000023205 | Potassium voltage-gated channel subfamily E member 1 isoform X1. | Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. | 0.983 |